LOCUS       Y17900                 14624 bp    DNA     linear   BCT 18-APR-2005
DEFINITION  Streptococcus salivarius CPS operon and flanking genes.
ACCESSION   Y17900
VERSION     Y17900.1
KEYWORDS    beta-glucosyltransferase; cpsA gene; cpsB gene; cpsC gene; cpsD
            gene; cpsE gene; cpsF gene; cpsG gene; cpsH gene; cpsI gene; cpsJ
            gene; cpsK gene; cpsL gene; hexose transferase; purine nucleotide
            prosphorylase; rhamnosyltransferase; transcription regulator;
            transport protein; transposase; undecaprenyl-phosphate
            glucosyl-1-phosphate transferase.
SOURCE      Streptococcus salivarius
  ORGANISM  Streptococcus salivarius
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Almiron-Roig E., Mulholland F., Gasson M.J., Griffin A.M.
  TITLE     The complete cps gene cluster from Streptococcus thermophilus NCFB
            2393 involved in the biosynthesis of a new exopolysaccharide
  JOURNAL   Microbiology (Reading, Engl.) 146, 2793-2802(2000).
   PUBMED   11065358
REFERENCE   3  (bases 1 to 9900)
  AUTHORS   Almiron-Roig E.
  JOURNAL   Submitted (06-AUG-1998) to the INSDC. E. Almiron-Roig, Institute of
            Food Research, Norwich Research Park, Colney Lane, NR4 7UA Norwich,
            UK
  REMARK    Rivised by author 11-JUN-99
COMMENT     Related sequence X94980
FEATURES             Location/Qualifiers
     source          1..14624
                     /organism="Streptococcus salivarius"
                     /sub_species="thermophilus"
                     /strain="NCFB 2393"
                     /isolate="isolate from dairy starter"
                     /mol_type="genomic DNA"
                     /clone_lib="LAMBDA DASH"
                     /clone="9L3"
                     /clone="3K1"
                     /db_xref="taxon:1304"
     CDS             1..711
                     /transl_table=11
                     /gene="deod"
                     /product="putative purine-nucleotide phosphorylase"
                     /db_xref="GOA:Q798Z6"
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR004402"
                     /db_xref="InterPro:IPR018016"
                     /db_xref="InterPro:IPR035994"
                     /db_xref="UniProtKB/TrEMBL:Q798Z6"
                     /protein_id="CAC18350.1"
                     /translation="MSIHIAAKQGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGERVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEDVHVRE
                     LVLAQAAATNSNIIRNDWPQYDFPQIANFNLLDKAYHIAKNFGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQHQVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAD"
     regulatory      981..986
                     /gene="cpsA"
                     /note="putative"
                     /regulatory_class="minus_35_signal"
     regulatory      1010..1015
                     /gene="cpsA"
                     /note="putative"
                     /regulatory_class="minus_10_signal"
     regulatory      1038..1042
                     /gene="cpsA"
                     /regulatory_class="ribosome_binding_site"
     CDS             1053..2513
                     /transl_table=11
                     /gene="cpsA"
                     /product="putative transcription regulator"
                     /db_xref="GOA:Q9EVX6"
                     /db_xref="InterPro:IPR004190"
                     /db_xref="InterPro:IPR004474"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX6"
                     /protein_id="CAC18351.1"
                     /translation="MSSRTNRKQKRTGNRSWGMVNVGLTILYAILALVLLFTMFNYNF
                     LSFRFLNIIITIGLLVVLAISIFLQKTKKSPLVTTVVLVIFSLVSLVGIFGFKQMIDI
                     TNRMNQTAAFSEVEMSIVVPKESDIKDVSQLTSVQAPTKVDKNNIETLMSALKKDKKV
                     DVKVDDVASYQEAYDNLKSGKSKAMVLSGSYASLLESVDSNYDSNLKTIYTYKIKKKN
                     NNSAKQVDSKVFNIYISGIDTYGSISTVSRSDVNIIMTVNMNTHKILLTTTPRDAYVK
                     IPGGGANQYDKLTHAGIYGVETSEQTLENLYGIKIDYYARINFTSFLKLIDQLGGVTV
                     HNDQAFTSLHGKFDFPVGDIQMNSEQALGFVRERYSLDGGDNDRGKNQEKVISAIVNK
                     LASLKSVSNFTSIVNNLQDSVQTNISLDTINALANTQLDSGSKFTVTSQAVTGTGSTG
                     QLTSYAMPNSSLYMMKLDNSSVASASQAIKNLMEEK"
     regulatory      2500..2505
                     /gene="cpsB"
                     /regulatory_class="ribosome_binding_site"
     CDS             2514..3245
                     /transl_table=11
                     /gene="cpsB"
                     /product="CpsB protein"
                     /note="unknown function"
                     /db_xref="GOA:Q55203"
                     /db_xref="InterPro:IPR016667"
                     /db_xref="InterPro:IPR032466"
                     /db_xref="UniProtKB/TrEMBL:Q55203"
                     /protein_id="CAC18352.1"
                     /translation="MIDVHSHIVFDVDDGPKTLEESLDLIGESYAQGVRKIVSTSHRR
                     KGMFETPEDKIFANFSKVKAEAEALYPDLTIYYGGELYYTLDIVEKLEKNLIPRMHNT
                     QFALIEFSARTSWKEIHSGLSNVLRAGVTPIVAHIERYDALEENADRVREIINMGCYT
                     QVNSSHVLKPKLFGDKDKVRKKRVRYFLEKNLVHMVASDMHNLGPRPPFMKDAYEIVK
                     KNYGSKRPKNLFIENPKTLIENQYL"
     regulatory      3244..3248
                     /gene="cpsC"
                     /regulatory_class="ribosome_binding_site"
     CDS             3254..3946
                     /transl_table=11
                     /gene="cpsC"
                     /product="CpsC protein"
                     /function="polymerization and, or export of
                     exopolysaccharide"
                     /note="putative"
                     /db_xref="GOA:Q55204"
                     /db_xref="InterPro:IPR003856"
                     /db_xref="InterPro:IPR005701"
                     /db_xref="InterPro:IPR032807"
                     /db_xref="UniProtKB/TrEMBL:Q55204"
                     /protein_id="CAC18353.1"
                     /translation="MNQDNTKSDEIDVLALLHKLWTKKLLILFTAFYFAAFSFLGTYF
                     FIQPTYTSTTRIYVVNQATDNNNLSAQDLQAGTYLVNDYKEIITSNDVLSEVIKDEKL
                     NMTEAELAKMISVNIPTDTRLISISVNAKTGQDAQTPANKVREVASEKIKKVTKVEDV
                     TTLEEAKLPESPSSPNIKLNVLLGAVLGAFLAVVGVLVREILDDRVRRPEDVEDALGM
                     TLLGIVPDTDKI"
     regulatory      3946..3950
                     /gene="cpsD"
                     /regulatory_class="ribosome_binding_site"
     CDS             3956..4696
                     /transl_table=11
                     /gene="cpsD"
                     /product="CpsD protein"
                     /function="polymerization and, or export of
                     exopolysaccharide"
                     /note="putative"
                     /db_xref="GOA:Q55205"
                     /db_xref="InterPro:IPR005702"
                     /db_xref="InterPro:IPR025669"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:Q55205"
                     /protein_id="CAC18354.1"
                     /translation="MPLLKLVKSKVDFAKKTEEYYNAIRTNIQFSGAQIKVIAISSVE
                     AGEGKSTTSVNLAISFASVGLRTLLIDADTRNSVLSGTFKSNEPYKGLSNFLSGNADL
                     NETICQTDISGLDVIASGPVPPNPTSLLQNDNFRHLMEVARSRYDYVIIDTPPVGMVI
                     DAVIISHQADASLLVTEAGKIKRRFVTKAVEQLEQSGSQFLGVVLNKVDMTVDKYGSY
                     GSYGSYGEYGKKSNQKEGHSRAHRRRKG"
     regulatory      4741..4745
                     /gene="cpsE"
                     /regulatory_class="ribosome_binding_site"
     CDS             4754..6121
                     /transl_table=11
                     /gene="cpsE"
                     /product="undecaprenyl-phosphate glucosyl-1-phosphate
                     transferase"
                     /db_xref="GOA:P72577"
                     /db_xref="InterPro:IPR003362"
                     /db_xref="InterPro:IPR017475"
                     /db_xref="UniProtKB/TrEMBL:P72577"
                     /protein_id="CAC18355.1"
                     /translation="MKEKQEIHRIEIGIIQLVVVVFAAMVASKIPYTEITQGSIVLLG
                     VIHVVSFYISSYYENLKYRGYLDELIATVKYCFIFALIATFLSFFADGSFSISRRGLL
                     YVTLISGVLLYVTNTVLKYFRSSIYTRRKSNKNILLISDQARLENVLSRMKDNMDGRI
                     TAVCVLDNPYFTDPFIKSVKPENLIEYATHSVVDQVLINLPSEQYKIWDYASPFEVMG
                     IPVSINLNALEFMSKGEKRIQQLGPFKVVTFSTHFYSYGDILAKRFLDICGALVGLVL
                     CGIVGIFLYPLIRKDGGPAIFAQDRVGENGRIFKFYKFRSMCVDAEEIKKNLMAQNQM
                     SGGMFKMDNDPRITKIGHFIRKTSLDELPQFWNVLKGDMSLVGTRPPTLDEYESYTPE
                     QKRRLSFKPGITGLWQVSGRSEITDFDEVVKLDVAYLDGWTIWRDIKILLKTIKVVVM
                     KDGAK"
     regulatory      6047..6052
                     /gene="cpsF"
                     /note="putative"
                     /regulatory_class="minus_35_signal"
     regulatory      6067..6072
                     /gene="cpsF"
                     /note="putative"
                     /regulatory_class="minus_10_signal"
     regulatory      6110..6113
                     /gene="cpsF"
                     /regulatory_class="ribosome_binding_site"
     CDS             6154..7326
                     /transl_table=11
                     /gene="cpsF"
                     /product="putative rhamnosyltransferase"
                     /db_xref="GOA:Q9EVX5"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR015393"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX5"
                     /protein_id="CAC18356.1"
                     /translation="MTKTVYIVGSKGIPAKYGGFETFVEKLTEFQQDKDIQYYVACMR
                     ENSAKSGIRADTFEHNGAKCYNIDVPNIGPARAIAYDIAAINKAIEIAKENNDQAPIF
                     YVLACRIGPFISGIKKKIKAIGGTLMVNPDGHEWLRAKWSLPVRKYWKISEQLMVKHA
                     DLLICDSKNIESYIQNDYAKYRPQTTYIAYGTDTTKSRLTKVDDKVRTWYFEKGVIEN
                     NYYLVVGRFVPENNYEAMIRGFMASNSDKDFVLVTNVEENKFYDKLRQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALESTKLNLLLDVGFNREVGE
                     DGALYWKKDQLASVINQAEQLDEQAIADLNQKSSKRIEEAFTWEKIVTDYEKVFKG"
     regulatory      7307..7312
                     /gene="cpsG"
                     /regulatory_class="ribosome_binding_site"
     CDS             7329..8474
                     /transl_table=11
                     /gene="cpsG"
                     /product="putative hexose transferase"
                     /db_xref="GOA:Q9EVX4"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="InterPro:IPR028098"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX4"
                     /protein_id="CAC18357.1"
                     /translation="MQKILYLHAGAEMYGADKVLLELIKGLDKEAFEAHVILPNDGVL
                     VGALEKVGAKVKVINYPILRRKYFNPKGILEYFGSYNRYSKKIAEYAKENGITLLHNN
                     TTAVLEGIYLKRKLKLPLIWHVHEIIVKPKAISDFINFLMGRYADTIVTVSNAVANHV
                     KQSRFVKNDQVQVIYNGVDNAVYHEMDASAVRDQFGIVQDALVIGMVGRVNAWKGQGN
                     FLEAVTPILKANPKAVAFLAGSAFEGEEWRVDELEKAISDSPVAGQIKRIDYYSKTTE
                     LYNMFDIFVLPSTNPDPLPTVVLEAMACGKPVVGYRHGGVCEMVKEGENGLLATPNQP
                     AELSKAIQELADNTEKREQFGKASVKRQKELFSLQSYIRNFSELYKK"
     regulatory      8579..8582
                     /gene="cpsH"
                     /regulatory_class="ribosome_binding_site"
     CDS             8595..9137
                     /transl_table=11
                     /gene="cpsH"
                     /product="CpsH protein"
                     /function="unknown"
                     /note="shows high homology to protein HI1244 from H.
                     influenzae"
                     /db_xref="InterPro:IPR015037"
                     /db_xref="InterPro:IPR037226"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX3"
                     /protein_id="CAC18358.1"
                     /translation="MICDNCWAGKVYQELGLPYQTPFVGMFVFSPDYIKMLKNLKYYL
                     SGNIPLTFVKESKYIKDFDNAYPLALLDDIELHFLHYADEEEATQKWERRLKRMHWDD
                     LYFKFNDNDACTYELMKEFEEHPYKSKVIFSSKNYSGLPSLVHFKSAEKQGHVGIDLK
                     TYHRYFNAVTWLNKGGEDLT"
     regulatory      9155..9158
                     /gene="cpsI"
                     /regulatory_class="ribosome_binding_site"
     CDS             9162..10136
                     /transl_table=11
                     /gene="cpsI"
                     /product="putative beta-glucosyltransferase"
                     /db_xref="GOA:Q9EVX2"
                     /db_xref="InterPro:IPR001173"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX2"
                     /protein_id="CAC18359.1"
                     /translation="MKPLLTVVIPVYNVEKYLKRCVESVLVQEWNNYDILLVDDGSID
                     SSPQICDDYVKAYDFISVIHKENGGLSEARNTGISNAEGEYVYFLDSDDWIEPNTFSD
                     LAEVIESDQYDIISFNQEFVKSEHDIIKSDSKRIKRLTGKEALIDMFSYGFITGFATD
                     KIYRKALFTKNTIQFPVGKYYEDLGTNYKLFLSAKKVYATNQKYYHYLIDNPDAITKS
                     WNEQKFSDMFEFYKDIFYSDFVGSQLNQEEIQILQLYYVNGLTHILASLYKSKLDKKY
                     IDITNKVKQELVKNSISLSQMKDQPNKLKYILFRLKLLKLAFSIQNVF"
     regulatory      10167..10172
                     /gene="cpsJ"
                     /note="putative"
                     /regulatory_class="minus_35_signal"
     regulatory      10194..10199
                     /gene="cpsJ"
                     /note="putative"
                     /regulatory_class="minus_10_signal"
     regulatory      10321..10324
                     /gene="cpsJ"
                     /regulatory_class="ribosome_binding_site"
     CDS             10329..11045
                     /transl_table=11
                     /gene="cpsJ"
                     /product="putative hexose transferase"
                     /db_xref="GOA:Q9EVX1"
                     /db_xref="InterPro:IPR021520"
                     /db_xref="InterPro:IPR031358"
                     /db_xref="UniProtKB/Swiss-Prot:Q9EVX1"
                     /protein_id="CAC18360.1"
                     /translation="MDFVVLWVDGNDPEFIREKNKYTPHNRKIDNDEDNVHRYRDYGT
                     FNYWFRMVERHAPWVNNIYLITNGQRPKWLNVNHPKLKWVRHEEFIPKEYLPIFNASA
                     IEMNIHRIDGLSENFVLFNDDMYLIQDVKYSDFFVNEKPKLLAIYEALVPWSRFSKIY
                     FNDVLVLYRHFPNKKALRQSPFKFFNIKYGQLMLKNRLHNFHGGFTHYRNYRAKIGRH
                     IWFFEGNFLFTSGTKCFQFI"
     regulatory      10858..10863
                     /gene="cpsK"
                     /note="putative"
                     /regulatory_class="minus_35_signal"
     regulatory      10882..10887
                     /gene="cpsK"
                     /note="putative"
                     /regulatory_class="minus_10_signal"
     regulatory      10917..10919
                     /gene="cpsK"
                     /regulatory_class="ribosome_binding_site"
     CDS             10933..11289
                     /transl_table=11
                     /gene="cpsK"
                     /product="transport protein homologue"
                     /db_xref="UniProtKB/TrEMBL:Q9EVX0"
                     /protein_id="CAC18361.1"
                     /translation="MVGLPTTEIIEPKLEDIFGFSKEIFYSQAVQSVFNSSELKILNC
                     FYTDNLIYVLTILYKTNLSEECKQLTMDVNSELRKNGVSLLRFKKRINFKKYVLYKLG
                     LLKLVFDLRLRMKRYR"
     regulatory      11288..11292
                     /gene="cpsL"
                     /regulatory_class="ribosome_binding_site"
     CDS             11297..12187
                     /transl_table=11
                     /gene="cpsL"
                     /product="CpsL protein"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW9"
                     /protein_id="CAC18362.1"
                     /translation="MRKILLLLEQIDSFEQFFAKSVSLPQVEVSTPYKKVHSQMAHKI
                     RAISKRLPFASLHQFWIAEWQKRIDDFDTIVVFDNAATQKLLEFIKSRITKRTKLKIW
                     LWNVPNERIEYLKENFDVYCFDQNYSKEYGLTFLEQFYILDSVNLDEKTDVLRDFYFV
                     GADKGRIQQLDQLAGMIEESELTYQFDVFSDDKQSNRSGINYLDSKITYPEIIKKIQE
                     SKVIVEINKDGQVGLTLRALESLFFQKKLITNKDRIGPFFMYVQCDEDTLLKVDKVSK
                     TEAQTFDVFNQLVSRFKFRV"
     mobile_element  11927..13405
                     /mobile_element_type="insertion sequence:IS1193"
     repeat_region   11927..11933
                     /rpt_type=DIRECT
                     /note="left"
     repeat_region   11944..11962
                     /rpt_type=INVERTED
                     /note="left"
     CDS             complement(12017..13261)
                     /transl_table=11
                     /gene="tnpIS1193"
                     /product="transposase"
                     /db_xref="GOA:Q9EVW8"
                     /db_xref="InterPro:IPR002560"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR029261"
                     /db_xref="InterPro:IPR032877"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW8"
                     /protein_id="CAC18363.1"
                     /translation="MGIKDQNIIISLIFETDTHIEIQAKLDYPAPSCPHCQEKMIKYD
                     FQKPSKIPLLEQAGTPTLLRLKKRRFQCKNCRRVTVAETSIVEKNCQISNLVRQKVTQ
                     LLTEKVSLTDIARRLRVSTSTVYCKLDQFTFKEHYDKLPTVMSWDEFGFKKGELAFVA
                     QKYETNELIIILDNRRQTTIRNYFLKYPLKVRQQVPFITMDMSGAYIPLSRRLFPNAK
                     IVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRLFQKDSCKLSLNSFYS
                     KTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDDFFELIEENRSKVNH
                     YFQTVFRTFLRHKQYIKNALETDYSNAKLEATNKLIKDIKRLGFGFRNFINFKKRVFI
                     TLNIHKKRTYPVLIGNQFFLEK"
     regulatory      12863..12867
                     /note="ORFM"
                     /regulatory_class="ribosome_binding_site"
     CDS             12894..13127
                     /transl_table=11
                     /product="hypothetical protein"
                     /note="ORFM"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW7"
                     /protein_id="CAC18364.1"
                     /translation="MDVDTRSLLAISVSDTFSVRSCVTFCRTRLEIWQFFSTIDVSAT
                     VTLLQFLHWKRRFFRRSRVGVPACSRRGILEGF"
     repeat_region   13370..13388
                     /rpt_type=INVERTED
                     /note="right"
     repeat_region   13399..13405
                     /rpt_type=DIRECT
                     /note="right"
     CDS             complement(13454..14029)
                     /transl_table=11
                     /product="hypothetical protein"
                     /note="ORF14.9"
                     /db_xref="GOA:Q9EVW6"
                     /db_xref="InterPro:IPR006976"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW6"
                     /protein_id="CAC18365.1"
                     /translation="MRKYMIYLSSLLVTFILSYATITWLIMPVLTRYQSLTRLINHFD
                     YTTLTLILLLTLIIWLFGIQYHLKHFSVIYLYLAFSVYLLLLFMVLFTKTTDFQAISL
                     NPFDFIKADTRTIQEAVLNIIYFIPLGGLYCINTDFKQFVIVSLVTLLGIETIQFIFY
                     LGTFAISDIILNFLGCLIGYYCCWEIKRRLS"
     regulatory      complement(14041..14046)
                     /note="ORFM"
                     /regulatory_class="ribosome_binding_site"
     mobile_element  14220..>14624
                     /mobile_element_type="insertion sequence:ISS1"
     repeat_region   14220..14236
                     /rpt_type=LONG_TERMINAL_REPEAT
                     /note="left"
     CDS             complement(14264..14491)
                     /transl_table=11
                     /gene="tnpISS1"
                     /product="transposase"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW5"
                     /protein_id="CAC18366.1"
                     /translation="MIKCHKLLTQKLAIANHLTTIFGYKMQAVKSLRTASSTIKGMET
                     LREIYKKNRRNGTLFDFSMSTEIKVLMGITA"
     regulatory      14315..14318
                     /note="ORFN"
                     /regulatory_class="ribosome_binding_site"
     CDS             14327..>14624
                     /transl_table=11
                     /product="hypothetical protein"
                     /note="ORFN"
                     /db_xref="UniProtKB/TrEMBL:Q9EVW4"
                     /protein_id="CAC18367.1"
                     /translation="MSSVLFIYFSKGLHALNRGRGCTETFDRLHFVAENGGQVVSYGK
                     LLCQEFMAFNDVEKLLRYFNYDLLDKPTIFNGAKSAYMLSGTKLHFGKEMIIEED"
BASE COUNT         4723 a         2311 c         2889 g         4701 t
ORIGIN      
        1 atgtctatcc atattgctgc taagcaaggt gaaattgctg ataaaattct cctacctgga
       61 gatcctttac gagcgaaatt cattgccgag aatttccttg aagatgctgt atgtttcaat
      121 gaagttcgta atatgtttgg ttacacagga acatacaagg gtgaacgtgt ctcagtaatg
      181 ggaactggaa tggggatgcc ttctatctct atctatgcac gtgagctcat tgttgactac
      241 ggtgtcaaaa aattaattcg cgtaggaact gctggctctt tgaatgagga tgttcacgtt
      301 cgtgagttgg ttctagcaca agctgcagca actaactcta atattattcg taatgactgg
      361 cctcaatacg actttcctca aattgcaaat ttcaatctct tggataaggc ttatcacatc
      421 gccaaaaatt ttggtatgac aacacatgtt ggtaatgttc tatcttctga tgttttctac
      481 tcaaattatt ttgaaaaaaa tattgaactt gggaaatggg gcgtgaaggc tgtcgaaatg
      541 gaagcagcag cactttacta ccttgcagcc caacaccaag tagatgctct ggctattatg
      601 actatttctg atagtttggt aaatccagat gaggacacaa cagctgagga acgtcaaaat
      661 actttcactg atatgatgaa agttggtctt gaaacactaa ttgcagacta gtttgtaaaa
      721 ggacgccatt tggtcgtcct tttgtgttgt agctaatatc tgttcgaagt gataataagt
      781 taaaattttt caaactacta gaaaaaataa aaatatttgg aagaagaaga cttttaataa
      841 ataggtaaat atctgacaat ttaaagttta actactaaaa atgtgaaaga tagttcacaa
      901 tataatggaa aatgatataa attaaatgat tgatatcata atgaaaacgt ttttttgttt
      961 ttttttgaaa aaaatgacaa ttgaaatgaa attgtattaa tgttacaata ataatgggga
     1021 atacttaatt ttaattttta ggagcaattt atatgagttc gcgtacgaat cgtaagcaaa
     1081 aacgtacggg taatagatca tgggggatgg tcaacgttgg attgaccatt ctgtatgcta
     1141 ttttagcatt ggtcttatta ttcaccatgt tcaattataa tttcctatcc tttaggtttt
     1201 tgaacatcat tatcactatt ggtttgttgg tagttcttgc tattagcatc ttccttcaga
     1261 agactaagaa atcaccacta gtgacaacgg ttgtattggt tatcttctcg ctagtttctc
     1321 tggttggtat ttttggtttt aaacaaatga ttgacatcac taaccgtatg aatcagacgg
     1381 cagctttttc tgaagtagaa atgagcatcg tggttcctaa ggaaagtgac atcaaagatg
     1441 tgagccagct tactagcgta caggcaccta ctaaggttga taagaacaat atcgagacct
     1501 tgatgtcggc tctcaaaaaa gataaaaaag ttgatgttaa agttgatgat gttgcctcat
     1561 atcaagaagc ttatgataat cttaagtctg gcaaatctaa agctatggtc ttgagtgggt
     1621 cttatgctag cctactagag tctgtcgata gtaattatga ttcaaatcta aaaacaatct
     1681 atacttataa aattaaaaag aagaataaca attctgcaaa acaagtagat tcaaaagtct
     1741 tcaatattta tattagtggt attgatacct acggttcaat ttcaacagtg tcacgttcag
     1801 atgtcaatat cattatgacc gttaacatga acacacataa gattctcttg acgactactc
     1861 cacgtgatgc atacgttaag attcctggtg gtggggcaaa ccagtatgat aaattaaccc
     1921 acgcaggtat ttatggcgtt gaaacatctg aacaaactct ggaaaatctt tatggtatta
     1981 agattgatta ctatgcacga attaacttca catctttcct taagttgatt gaccaacttg
     2041 gtggtgtgac agtccataat gatcaagctt tcacaagtct tcatgggaag tttgatttcc
     2101 cagttggaga tatccaaatg aattcagagc aagcacttgg atttgttcgt gaacgctata
     2161 gtttagatgg cggagataat gaccgtggta aaaaccagga gaaagtcatt tctgcgattg
     2221 taaacaagtt ggcttctcta aagtctgtat caaactttac ttcaatcgtt aataatctcc
     2281 aagactctgt tcagacaaat atttctttgg ataccattaa tgctttggct aatacacaac
     2341 ttgattcagg ctctaaattt acagtaacgt ctcaagcagt aactggtaca ggttcaaccg
     2401 gacaattgac ctcttatgcg atgccaaatt ctagtcttta catgatgaaa ctagataatt
     2461 cgagtgtggc aagtgcctct caagctatca aaaatctaat ggaggaaaaa taagtgattg
     2521 acgttcactc acatattgtt tttgatgttg atgatggtcc taaaacttta gaagaaagtt
     2581 tagatctcat tggtgaaagt tacgcccagg gggtacgtaa gattgtttca acatcccatc
     2641 gtcgtaaggg gatgtttgag actccagagg ataaaatttt tgccaacttt tctaaggtaa
     2701 aagcagaagc agaagcactt tatccagact taactattta ttatggaggt gaactttatt
     2761 acaccttaga cattgtggag aaacttgaaa agaatctcat tccgcgcatg cacaacactc
     2821 aatttgcttt gattgagttt agtgctcgca catcttggaa agaaattcat agtgggctta
     2881 gtaatgtttt gagagcgggg gtaacgccta ttgttgctca tattgagcgc tatgatgccc
     2941 tcgaagaaaa tgctgaccgt gttcgagaaa tcatcaacat ggggtgctat actcaagtta
     3001 atagctctca tgttctaaaa ccaaagctct ttggagataa agataaagta agaaaaaaac
     3061 gtgttcgtta ttttttggag aaaaatttgg ttcatatggt tgctagcgac atgcataatc
     3121 ttgggccgag accaccattt atgaaagatg cttatgaaat tgttaaaaag aactacggct
     3181 ccaaacgtcc taagaatctt tttattgaaa atcccaaaac attaatagaa aatcaatatt
     3241 tataggagat attatgaatc aagataacac taaaagtgat gaaatcgacg tactagcatt
     3301 gctacataaa ctttggacga agaagctttt gattcttttc acagcttttt atttcgctgc
     3361 tttcagtttc ttaggtactt atttctttat ccaaccaaca tatacatcaa caacgcgtat
     3421 ctatgttgtt aatcaggcaa cagataataa taatctttct gctcaagatt tgcaagctgg
     3481 tacctatttg gtaaatgact ataaagaaat tattacatca aatgatgtct tgtcagaagt
     3541 tatcaaagat gaaaaattga atatgacaga agcagaactt gctaaaatga tttcagttaa
     3601 tattcctact gatactcgtc ttatttcaat ttctgttaat gctaaaactg gtcaagatgc
     3661 gcaaacacct gccaataagg ttcgtgaagt tgcttcagaa aaaatcaaga aggtgacaaa
     3721 agttgaagat gtcacaacgc tcgaagaagc taaattgcca gaatcaccat cttcaccaaa
     3781 tatcaaactt aatgtgcttc ttggggcagt gcttggagca ttccttgcag tggttggtgt
     3841 attggtacgt gaaatcctag atgatcgtgt tcgccgtcca gaagatgtgg aagatgccct
     3901 tggaatgaca cttcttggaa ttgtccctga tacagataaa atttaaggag aagaaatgcc
     3961 tttattaaag ttagttaaat caaaagtaga ctttgctaaa aagacggaag agtattataa
     4021 cgctattcgc acaaatattc aattttctgg tgctcagatt aaagtgattg cgattagctc
     4081 tgttgaagct ggtgaaggaa aatcaacgac atctgttaac ttggcgattt catttgctag
     4141 tgttgggctc cgaacacttc tgattgatgc ggatacgcgt aattctgttt tgtcaggtac
     4201 atttaaatca aatgagcctt ataaaggtct ttcaaatttc ctttcaggaa atgccgatct
     4261 aaatgaaacg atttgccaaa ctgatatttc tggtttagat gttattgcat ctggtcctgt
     4321 tccacctaat ccaacaagtc ttttgcaaaa tgacaatttt agacatttga tggaagttgc
     4381 tcgtagtcgt tatgattatg tcatcatcga tacaccacca gttggtatgg ttattgatgc
     4441 agttattatt tcccatcagg ctgatgccag tcttttggtt acagaagctg ggaaaatcaa
     4501 acgtcgtttc gtaactaagg ccgttgaaca attggaacaa agtggttctc agttcttagg
     4561 ggtcgtcctt aataaagttg acatgacagt tgataaatat ggatcgtatg gttcttacgg
     4621 atcatatggc gagtatggaa aaaaatctaa ccaaaaagaa ggtcattcaa gagcacatcg
     4681 tcgtagaaaa ggatagcatt aatggggatg atgcggttcc ttataacctt aacagattaa
     4741 aaaggggttt agagtgaaag aaaaacaaga aattcatcgc attgaaattg gtattataca
     4801 gttggttgtg gttgtttttg cagccatggt agctagtaaa ataccttata cagagattac
     4861 ccaaggaagc attgtccttt taggtgtcat acatgtagtg tctttctata tcagtagtta
     4921 ttatgaaaat cttaagtata gaggctactt ggatgaactc attgcaactg tcaaatattg
     4981 tttcatattt gctctaattg caacatttct ctcgtttttt gcagatggaa gtttttcaat
     5041 ctcacgtcgc ggacttcttt acgtcaccct gatttcaggt gttctcttat acgttacaaa
     5101 tactgttctt aagtatttcc gttcatctat ttatacacgt cgtaaaagta acaagaatat
     5161 tctcttgatt tctgatcaag cacgtctaga aaatgttttg tctcgtatga aagacaatat
     5221 ggatggtagg attacagcag tttgtgtctt ggataatcct tatttcacgg atccatttat
     5281 caagagtgtt aaacctgaaa atttgattga atatgcgaca cactcagtag tagaccaagt
     5341 tttgattaat ctgccaagtg agcagtacaa gatttgggat tatgcatcac cttttgaagt
     5401 tatggggatt ccagtatcca ttaatttgaa tgcacttgaa tttatgagta agggtgaaaa
     5461 gcgtatccaa caattgggtc ctttcaaagt tgttacgttt tcaacgcatt tttatagcta
     5521 tggagatatc ttggcgaaac gtttcctcga tatctgtgga gccctagttg gtttggtgct
     5581 ctgtgggatt gttggaatct tcctttatcc acttattcgt aaggatggtg ggccagccat
     5641 ttttgctcaa gaccgtgtgg gagaaaatgg acgtatcttc aagttttata aattccgttc
     5701 tatgtgtgtt gatgcggaag aaatcaagaa gaatttgatg gcacagaatc aaatgtctgg
     5761 tggtatgttt aagatggaca atgatccacg tattaccaaa attggacatt tcattcgtaa
     5821 aacgagtctt gatgaacttc cacaattttg gaatgttcta aaaggtgata tgagcttggt
     5881 aggaacacgt ccaccaacat tggatgagta cgaatcttat acaccggaac aaaaacgtcg
     5941 cctcagcttt aaaccaggta ttactggtct ttggcaagta agcggtcgaa gtgaaattac
     6001 tgattttgat gaagttgtaa aactagacgt tgcttatttg gacggatgga caatctggcg
     6061 cgatattaaa atcttattga aaacaattaa agtagtagta atgaaggatg gagcaaagtg
     6121 atggctttct ccatttcttt taatggtgat taaatgacaa aaacagttta tatcgttggt
     6181 tctaagggaa ttccagcaaa atatggtgga tttgagacct ttgttgagaa gttgacagag
     6241 ttccaacaag acaaagatat ccaatattat gtagcttgta tgcgtgaaaa ttctgctaaa
     6301 tcaggaatta gagcagatac tttcgaacat aacggtgcta aatgctacaa tattgatgtc
     6361 ccaaatatcg ggcctgcacg tgccatcgct tatgatatcg cagctattaa taaggccatt
     6421 gagattgcta aggaaaataa tgaccaagca ccgatctttt atgttttggc ctgccgaatt
     6481 ggtccattta tctcaggtat taaaaagaaa attaaggcta tcggtggtac ccttatggtt
     6541 aacccggatg gtcatgaatg gcttcgtgca aagtggagtc ttccggttcg taagtattgg
     6601 aaaatttcag agcaactcat ggttaaacat gcagatctct tgatttgtga tagtaaaaac
     6661 attgaatctt atattcaaaa tgattatgcg aaatatcgac ctcaaacaac ctatatcgcc
     6721 tatggaactg atacaactaa atctcgattg actaaggttg atgataaggt acgcacatgg
     6781 tattttgaaa agggggtcat tgaaaacaat tattaccttg ttgtaggacg cttcgtgcct
     6841 gaaaataact atgaggctat gattcgtggc tttatggcgt ctaactctga caaggacttt
     6901 gttctcgtta ctaatgttga agaaaataag ttctacgaca agttgcgtca ggaaactggt
     6961 tttgacaagg atcctcgtgt gaagtttgtc ggaactgttt atgaccaaga attgctcaag
     7021 tacattcgtg agaatgcctt tgcttatttc catggtcatg aggttggtgg aaccaatcca
     7081 tcacttcttg aggcacttga gtcaactaag ctcaatctct tgttggatgt tggctttaac
     7141 cgtgaagtcg gtgaagatgg tgctctctat tggaaaaaag accaattggc aagtgtcatt
     7201 aatcaagctg aacaattgga tgaacaagct atcgcagacc tcaatcaaaa atcaagtaaa
     7261 cgtatcgaag aagcctttac ttgggaaaaa attgttacag actacgagaa agtatttaaa
     7321 gggtagaaat gcagaaaatt ttatatcttc acgctggtgc cgaaatgtat ggtgctgata
     7381 aggttttgtt ggagcttatt aaaggactgg ataaagaagc ctttgaggct catgtcatct
     7441 tgcccaacga tggcgtctta gtgggtgcat tggaaaaggt tggtgctaag gtaaaagtta
     7501 tcaattatcc aatcttgcgc cggaagtatt ttaatcctaa gggaattctt gagtattttg
     7561 gctcatataa tcgttattca aagaaaatcg ccgaatatgc taaggaaaat ggaattactc
     7621 tccttcacaa taatactact gcagtacttg aggggattta tctcaaacgt aagttgaaac
     7681 ttcctttgat ttggcatgtt cacgagatta tagtcaaacc aaaagcaatc tctgatttca
     7741 tcaacttttt gatggggcgt tatgctgata cgattgtgac agtttcaaat gctgtggcca
     7801 accacgtgaa gcagtctcgc tttgtaaaaa atgaccaagt tcaggtcatc tataatggtg
     7861 ttgacaatgc cgtctatcat gaaatggatg ccagcgcagt tcgtgaccag tttggtatcg
     7921 tacaggatgc cttggttatc ggaatggttg gtcgagtgaa tgcatggaaa ggtcaaggca
     7981 acttcttaga agccgtgact ccaatcttaa aggctaatcc aaaagcagta gcctttctgg
     8041 cagggagtgc ttttgaaggt gaagagtggc gtgttgatga gttggaaaag gctatatcag
     8101 actcaccagt agctggacaa atcaaacgta tcgattatta tagcaagacg acagagctct
     8161 ataatatgtt tgatatcttt gtcttgccaa gtaccaatcc agatccccta cctactgtag
     8221 ttctcgaagc catggcttgt ggcaaacctg tagtcggcta ccgtcatggt ggtgtctgcg
     8281 aaatggttaa ggaaggtgaa aatggtcttc ttgccacacc aaatcagcct gcagaattat
     8341 cgaaggccat tcaagaattg gctgataaca ccgagaagag agagcaattt ggcaaggcct
     8401 ctgtcaaacg ccaaaaagaa ctcttttcat tacaaagtta tattcgtaat ttctcggagt
     8461 tatataagaa ataaaaagaa gtactaagaa gtaataatat gaacagcgaa acactaaaaa
     8521 aataaattaa aaccaatcgt ttatccaatt attaatttta ttcctagacg aagacttaag
     8581 aataaaattt tactatcatt tgtgataatt gttgggctgg aaaagtctat caggaattgg
     8641 gtttgcctta tcaaacgcca tttgtaggga tgtttgtctt ttctcccgat tacataaaga
     8701 tgctcaagaa tttaaaatac tatttgagtg gtaatatccc tttgacattt gttaaggaat
     8761 caaaatacat taaagacttt gataatgctt atccacttgc acttcttgac gatattgaac
     8821 ttcatttttt gcattatgca gatgaagaag aagctactca aaaatgggaa cgccgattga
     8881 agagaatgca ttgggatgat ctatatttca agttcaatga taatgatgcc tgcacgtatg
     8941 agttgatgaa agagtttgaa gagcatccat acaagagtaa ggtgattttc tcttcgaaga
     9001 attacagtgg tctaccttca ttggtccact ttaaatcagc tgagaagcaa ggacatgttg
     9061 gaattgattt gaaaacttac caccgttatt ttaatgctgt aacttggttg aataagggcg
     9121 gggaagattt aacataaaat aaaaatttag gtgaagaatc catgaaacca cttttaactg
     9181 ttgtaattcc agtttataat gtcgaaaagt atttaaaacg ttgtgtagaa agcgttcttg
     9241 tccaagagtg gaataattat gatattttac ttgtagatga tggaagtatt gatagttctc
     9301 ctcaaatctg tgatgattac gttaaagctt atgactttat ctcagtaatt cataaagaaa
     9361 atggagggct ttctgaagct cgtaacacag gtatttctaa tgctgaggga gaatatgttt
     9421 atttcctaga ttcagatgat tggattgaac cgaatacctt tagtgattta gctgaggtta
     9481 ttgaatcaga tcagtatgat attatttctt tcaatcaaga atttgtaaag agtgaacatg
     9541 atattataaa atccgattca aaacggatta aacgattaac tggaaaagaa gctcttatag
     9601 atatgttttc ttatggattt attactggtt ttgccactga taagatatat cgaaaagcat
     9661 tgttcactaa gaatactatc cagtttccag ttggcaagta ttatgaggac cttggtacca
     9721 attacaaact ctttctttct gctaagaagg tctacgcgac gaatcaaaag tactaccatt
     9781 atctaatcga taatccagat gcaattacca aatcatggaa tgagcagaag tttagtgata
     9841 tgtttgaatt ttataaagat attttctatt ctgattttgt tggttctcaa ttgaatcaag
     9901 aagaaataca aattttacag ctatattatg tgaatggctt gactcatatc ttggcaagtt
     9961 tatataaatc taaattagat aaaaaatata tagacattac taataaagta aaacaagaat
    10021 tagttaagaa tagtatttct ctttctcaaa tgaaagacca accaaataag ttaaaatata
    10081 tactgtttag acttaaattg ttaaaactag ccttcagtat acaaaatgtt ttttgatgtt
    10141 attttaaaaa attattctga gattcttagg caaatggggg ttggactatt ttatttaata
    10201 aagaaaagta acatattttt tggtctttct tctttttggt gtatggaatg atgtactttt
    10261 aactaaaaat tttatatagc tagacttggt aaacaattat tttataggta atttaatatg
    10321 gaaaaaaaat tgatttcgtt gtactttggg ttgatggaaa cgatccagaa tttattagag
    10381 aaaaaaataa atacacacct cacaatagga aaatcgataa tgatgaagat aatgtgcacc
    10441 gttatcgtga ctatggcaca ttcaattatt ggtttcgaat ggtagagagg catgcaccgt
    10501 gggtaaataa tatttatctt attactaacg gtcaaagacc gaaatggtta aatgtaaatc
    10561 atcctaaact taaatgggtt agacatgaag aatttattcc aaaggaatat cttccaatat
    10621 tcaatgcttc tgcaattgag atgaatatac atcggataga tggtttatct gaaaatttcg
    10681 ttctgtttaa tgatgatatg tacctaatcc aagatgttaa atatagtgat ttttttgtca
    10741 atgaaaaacc caagttgtta gctatttatg aagccttagt tccatggtct cgtttttcaa
    10801 aaatttattt taatgatgta cttgttcttt ataggcattt tccaaataaa aaagccttga
    10861 gacagtcacc atttaagttt tttaatatta aatatggcca attgatgcta aaaaataggc
    10921 tccataattt ccatggtggg tttacccact acagaaatta tagagccaaa attggaagac
    10981 atatttggtt tttcgaagga aattttttat tcacaagcgg tacaaagtgt tttcaattca
    11041 tctgagttaa aaatattgaa ttgtttttat acagataatc ttatctatgt tcttacaatt
    11101 ttatataaaa cgaatttatc agaagagtgt aagcaactaa ctatggatgt taattcagaa
    11161 ctaaggaaga atggagtatc gttattaagg ttcaaaaaac gtataaattt caagaaatat
    11221 gtgctgtaca agctgggctt gttgaagtta gtttttgact tacgattaag aatgaagaga
    11281 taccgataga aatattatga gaaaaatact actactactg gagcaaattg attcctttga
    11341 gcaatttttt gcgaaaagtg tgtcgcttcc tcaagtcgag gtttcaacac cttataagaa
    11401 agttcattca cagatggcgc acaaaatacg ggctatatca aaacgtctac cgtttgcttc
    11461 tttacatcaa ttttggattg cagagtggca aaaacgaata gatgattttg acactatagt
    11521 tgtttttgat aatgcagcaa cgcagaaact attagaattt attaaatctc ggataacgaa
    11581 gcgaacaaaa ttaaaaattt ggctttggaa tgttcccaat gagagaattg aatatttgaa
    11641 agaaaatttt gatgtttatt gttttgatca gaattattca aaggagtatg ggctaacctt
    11701 tttggaacag ttttacattt tggatagtgt taatcttgat gaaaaaacag atgtcttgcg
    11761 agatttttat tttgttggag ctgataaagg tcgtatacag caactggatc aattagctgg
    11821 aatgatagag gaatcagagt tgacctatca gtttgatgtt tttagtgacg ataaacagtc
    11881 caatcgtagt ggaataaatt atcttgatag taaaattacc taccctgaaa ttatcaagaa
    11941 aattcaagaa tcaaaagtga ttgtagaaat taataaagac gggcaagtag gtctgacttt
    12001 acgagcttta gaatcgttat ttttccaaaa aaaattgatt accaataagg accggatagg
    12061 tccttttttt atgtatgttc agtgtgatga agacacgctt cttaaagttg ataaagtttc
    12121 taaaaccgaa gcccaaacgt ttgatgtctt taatcaactt gttagtcgct tcaagtttcg
    12181 cgtttgaata gtccgtttct agtgcgtttt tgatgtattg cttgtgtcta agaaaagtcc
    12241 taaagacagt ttgaaaataa tgattgacct tgctcctatt ttcctctatc agttcaaaga
    12301 aatcatctac tctcttctcc tgaaagtgaa aaagcaaaag ctgataaagt gtatagtagt
    12361 cagtaagctc ttttgaaaag actagtgtct tcgcaacaac ttcatgtggt gctaaagttt
    12421 ggcggaaagt ctttgaataa aaagaattga gagatagttt acagctgtcc ttttggaaga
    12481 gtcgccagtg atttttcaag gctcgatagg gtagtgactt cttatcgaat tggttcatga
    12541 ttgcaattct agtctttaaa aatgctctac caaggtgctg gataatgtgg aaacgatcaa
    12601 gaacgatttt ggcgtttgga aagagtctgc gggatagtgg gatataggct ccagacatat
    12661 ccatcgtgat aaacggcacc tgttgtcgga ctttcaatgg atacttcaaa aagtagtttc
    12721 gtatagtagt ttggcggcga ttatcaagga tgattatgag ttcgtttgtc tcatactttt
    12781 gagctacaaa agccaactct cctttcttga aaccaaactc atcccaggac ataacagtag
    12841 ggagtttgtc ataatgttcc ttgaaagtaa actgatcaag cttacaatag acagtggacg
    12901 tcgacacgcg aagtcttctt gcaatatcag ttagtgacac tttctcagtt aggagttgtg
    12961 taactttttg tcggactaga ttggagattt ggcagttttt ctcaacgata gatgtctcag
    13021 ccaccgttac tctcctacaa tttttacact ggaaacgacg ttttttcaga cgtagtagag
    13081 ttggcgttcc cgcttgctcg agaagaggga ttttagaagg cttttgaaag tcgtacttga
    13141 tcatcttttc ttggcaatga ggacatgatg gtgcagggta atcaagtttt gcttgaatct
    13201 cgatatgagt gtcagtttca aaaataagtg aaataatgat attttggtct ttaattccga
    13261 ttaattatgt ggtattctta ataggtctca taagttcttc ctaatggtag tttcgtcgct
    13321 tttcattata gttcttatgg gactttttgt ctgcattcaa aaagctctat aatctctaca
    13381 atggttttac ccactacaga aattatagag ccaatatatc tactgtctat ttttatgcta
    13441 cttttgggtt agctcaactc aaccgccttt taatctccca acaacaataa tacccaatta
    13501 aacaacccaa gaaattcaag ataatatcac taatggcaaa tgtgcccaaa taaaagataa
    13561 attgaatggt ttcaattcct aaaagtgtga ccaaactgac aatgacaaac tgtttgaaat
    13621 cagtattgat acagtaaagg ccacctaaag gaatgaagta gataatattt agcactgcct
    13681 cttgaatcgt tctggtatcc gcttttataa agtcaaaagg attaagtgat atcgcctgaa
    13741 aatccgttgt tttagtaaaa agcaccatga ataacagtaa taaatacaca ctgaaagcaa
    13801 gatagagata aataactgaa aaatgtttga ggtgatactg gatgccaaac aaccagataa
    13861 tcagcgttaa taagagtatt aaagttaatg tggtatagtc aaagtggtta atcaacctag
    13921 tcaggctttg atagcgagtg agaacgggca taatcagcca agtaatcgtc gcataactca
    13981 ggataaatgt gaccaataaa ctgctgaggt agatcatata ttttcgcaac tgtttctaac
    14041 tccttttctt gatgagatta accctatttt aacatatttt aaaactgtca tgtttttatg
    14101 aatttaaaat aaagttcaat aaattttttg aaaattttgg aaaaaggcgt ataataaaat
    14161 catgaacgta tgactcaggt aagatatcaa ggaggatatc agatgacatg gttctgttgc
    14221 aaagtttgaa aatcaaacgc gccctctctg aactcaaaat atcttaggct gttattccca
    14281 ttaatacctt gatttcagta gacatcgaaa agtcaaagag cgttccattt cttcggttct
    14341 ttttatatat ttctcgaagg gtctccatgc ccttaatcgt ggaagaggct gtacggagac
    14401 ttttgaccgc ctgcattttg tagccgaaaa tggtggtcag gtggttagct atggcaagct
    14461 tctgtgtcag gagtttatgg catttaatga tgttgaaaaa ttactaagat attttaatta
    14521 tgatttgtta gataaaccga ctatatttaa tggtgctaaa tctgcttata tgctatcagg
    14581 aacgaaacta cattttggta aagagatgat aatagaagaa gatc
//