LOCUS       X52882                  2019 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for t-complex polypeptide 1 (TCP1 gene).
ACCESSION   X52882
VERSION     X52882.1
KEYWORDS    t-complex polypeptide 1; TCP1 gene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Kirchhoff C., Willison K.
  JOURNAL   Submitted (08-MAY-1990) to the INSDC. Kirchhoff C., Willison K.,
            Institute for Hormone and Fertility Research, Grandweg 64, D-2000
            Hamburg, FRG.
  REMARK    replaced by [2]
REFERENCE   2  (bases 1 to 2019)
  AUTHORS   Kirchhoff C., Willison K.
  TITLE     Nucleotide and amino-acid sequence of human testis-derived TCP1
  JOURNAL   Nucleic Acids Res. 18(14), 4247-4247(1990).
   PUBMED   2377466
COMMENT     For related sequences see <X14983>-<X14990>, <M26885>-<M26890>,
            <M27270>-<M27272>.
FEATURES             Location/Qualifiers
     source          1..2019
                     /db_xref="H-InvDB:HIT000321801"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /dev_stage="adult"
                     /clone_lib="lambda-gt11"
                     /tissue_type="testis"
                     /db_xref="taxon:9606"
     precursor_RNA   1..1781
                     /note="primary transcript"
     CDS             22..1692
                     /gene="TCP1"
                     /product="t-complex polypeptide 1"
                     /db_xref="GOA:P17987"
                     /db_xref="H-InvDB:HIT000321801.14"
                     /db_xref="HGNC:HGNC:11655"
                     /db_xref="InterPro:IPR002194"
                     /db_xref="InterPro:IPR002423"
                     /db_xref="InterPro:IPR012715"
                     /db_xref="InterPro:IPR017998"
                     /db_xref="InterPro:IPR027409"
                     /db_xref="InterPro:IPR027410"
                     /db_xref="InterPro:IPR027413"
                     /db_xref="PDB:6NR8"
                     /db_xref="PDB:6NR9"
                     /db_xref="PDB:6NRA"
                     /db_xref="PDB:6NRB"
                     /db_xref="PDB:6NRC"
                     /db_xref="PDB:6NRD"
                     /db_xref="PDB:6QB8"
                     /db_xref="UniProtKB/Swiss-Prot:P17987"
                     /protein_id="CAA37064.1"
                     /translation="MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKM
                     LVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLK
                     NADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKI
                     IGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNC
                     VVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQ
                     KILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANL
                     EGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSL
                     HDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPN
                     TLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTI
                     VKVKSLKFATEAAITILRIDDLIKLHPEILRIKHGSYEDAVHSGALND"
     old_sequence    1630..1641
                     /replace="agtaaagatgat"
                     /citation=[1]
     regulatory      1760..1765
                     /gene="TCP1"
                     /regulatory_class="polyA_signal_sequence"
BASE COUNT          608 a          379 c          461 g          571 t
ORIGIN      
        1 acgtgtatcg ctgccgtcaa gatggagggg cctttgtccg tgttcggtga ccgcagcact
       61 ggggaaacga tccgctccca aaacgttatg gctgcagctt cgattgccaa tattgtaaaa
      121 agttctcttg gtccagttgg cttggataaa atgttggtgg atgatattgg tgatgtaacc
      181 attactaacg atggtgcaac catcctgaag ttactggagg tagaacatcc tgcagctaaa
      241 gttctttgtg agctggctga tctgcaagac aaagaagttg gagatggaac tacttcagtg
      301 gttattattg cagcagaact cctaaaaaat gcagatgaat tagtcaaaca gaaaattcat
      361 cccacatcag ttattagtgg ctatcgactt gcttgcaagg aagcagtgcg ttatatcaat
      421 gaaaacctaa ttgttaacac agatgaactg ggaagagatt gcctgattaa tgctgctaag
      481 acatccatgt cttccaaaat cattgggata aatggtgatt tctttgctaa catggtagta
      541 gatgctgtac ttgctattaa atacacagac ataagaggcc agccacgcta tccagtcaac
      601 tctgttaata ttttgaaagc ccatgggaga agtcaaatgg agagtatgct catcagtggc
      661 tatgcactca actgtgtggt gggatcccag ggcatgccca agagaatcgt aaatgcaaaa
      721 attgcttgcc ttgacttcag cctgcaaaaa acaaaaatga agcttggtgt acaggtggtc
      781 attacagacc ctgaaaaact ggaccaaatt agacagagag aatcagatat caccaaggag
      841 agaattcaga agatcctggc aactggtgcc aatgttattc taaccactgg tggaattgat
      901 gatatgtgtc tgaagtattt tgtggaggct ggtgctatgg cagttagaag agttttaaaa
      961 agggacctta aacgcattgc caaagcttct ggagcaacta ttctgtcaac cctggccaat
     1021 ttggaaggtg aagaaacttt tgaagctgca atgttgggac aggcagaaga agtggtacag
     1081 gagagaattt gtgatgatga gctgatctta atcaaaaata ctaaggctcg tacgtctgca
     1141 tcgattatct tacgtggggc aaatgatttc atgtgtgatg agatggagcg ctctttacat
     1201 gatgcacttt gtgtagtgaa gagagttttg gagtcaaaat ctgtggttcc cggtgggggt
     1261 gctgtagaag cagccctttc catatacctt gaaaactatg caaccagcat ggggtctcgg
     1321 gaacagcttg cgattgcaga gtttgcaaga tcacttcttg ttattcccaa tacactagca
     1381 gttaatgctg cccaggactc cacagatctg gttgcaaaat taagagcttt tcataatgag
     1441 gcccaggtta acccagaacg taaaaatcta aaatggattg gtcttgattt gagcaatggt
     1501 aaacctcgag acaacaaaca agcaggggtg tttgaaccaa ccatagttaa agttaagagt
     1561 ttgaaatttg caacagaagc tgcaatcacc attcttcgaa ttgatgatct tattaaatta
     1621 catccagaaa tccttcggat taaacatgga agttatgaag atgctgttca ctctggagcc
     1681 cttaatgatt gatctgatgt tccttttatt tataacaatg ttaaatgcaa tgtcttgtac
     1741 cttgagttga gtattacaca ttaaagtaaa gtacaagctg taaacttggg tttttgtgat
     1801 gtaggaaatg gtttccatct gtactttggt cctctgattt cagatattgc aacctagtac
     1861 tttattagtt taaaaagaaa ttgaggttgt tcaaagttta agcaattcat tctctctgaa
     1921 cacacattgc tattcccatc ccacccccaa tgcacagggc tgcaacacca cgacttctgc
     1981 ccattctctc cagtgtgtgt aacagggtca caagaattc
//