LOCUS       X05592                  2206 bp    DNA     linear   VRL 19-MAR-1997
DEFINITION  Human spumaretrovirus DNA with 3' LTR.
ACCESSION   X05592 Y00070
VERSION     X05592.1
KEYWORDS    bel1 gene; bel2 gene; bel3 gene; long terminal repeat; overlapping
            genes; unidentified reading frame.
SOURCE      Human spumaretrovirus
  ORGANISM  Human spumaretrovirus
            Viruses; Ortervirales; Retroviridae; Spumaretrovirinae; Spumavirus.
REFERENCE   1  (bases 1 to 2206)
  AUTHORS   Flugel R.M., Rethwilm A., Maurer B., Darai G.
  TITLE     Nucleotide sequence analysis of the env gene and its flanking
            regions of the human spumaretrovirus reveals two novel genes
  JOURNAL   EMBO J. 6(7), 2077-2084(1987).
   PUBMED   2820721
COMMENT     Recombinant clones that represent the 3' part of the genome of the
            human spumaretrovirus (foamy virus) were established from cDNA
            (clone C55) and viral DNA (clone B52).
            See X05591 for C55 sequence.
            There are 12 octamer sequences, 6 nonamers and one decamer that
            form direct repeats within the LTR. The indirect repeats include a
            decamer with a loop size of 78bp and two octamers with a relatively
            small loop size of 34 and 5bp, respectively.
            
            Data kindly reviewed (02-SEP-1987) by Fluegel R.M.
            
            See U21247 which contains the corrected nucleotide sequence.
FEATURES             Location/Qualifiers
     source          1..2206
                     /organism="Human spumaretrovirus"
                     /mol_type="genomic DNA"
                     /clone="C55"
                     /cell_type="HSRV-infected HEL fibroblasts"
                     /db_xref="taxon:11963"
     CDS             <25..>1116
                     /codon_start=1
                     /note="unidentified reading frame; no ATG; put. bel-2 gene
                     product (AA 1-364)"
                     /db_xref="GOA:P89873"
                     /db_xref="InterPro:IPR004956"
                     /db_xref="UniProtKB/Swiss-Prot:P89873"
                     /protein_id="CAA29088.1"
                     /translation="NINPSEELLDLLCLLCINIKETVLLLNLLPVAQKVQNQDLGTIL
                     SFAVTCLKSITSLGRNDPGDDPSIMSHVLPVVTPWSMSHDHYAPTLFGILDRYYQGYL
                     KSPATYQTWKFTCQVDPSGKRFMETQFWVPPLGQVNIQFYKNYQILTCCQAVDPFANI
                     FHGTDEEMFDIDSGPDVWCSPSLCFKVIYEGAMGQKQEQKTWLCRLGHGHRMGACDYR
                     KVDLYAMRQGKENPYGDRGDAALQYAYQVKRGCKAGCLASPVLNYKALQFHRTIMADF
                     TNPRIGEGHLAHGYQAAMEAYGPQRGSNEERVWWNVTRNQGKQGGEYYREGGEEPHYP
                     NTPAPHRRTWDERHKVLKLSSFATPSDIQR"
     misc_feature    42..43
                     /note="pot. splice acceptor site"
     CDS             <701..>1202
                     /codon_start=1
                     /note="unidentified reading frame; bel-3 gene product"
                     /db_xref="GOA:P14355"
                     /db_xref="UniProtKB/Swiss-Prot:P14355"
                     /protein_id="CAA29089.1"
                     /translation="DKEKKTLMEIGVMQLCNMLIRLKGAVKQGAWHHLYLTTKLCSFI
                     EPLWQTSPILGLEKDILLMVTKQLWKLMDLREEVTRRGCGGMSLETRENKEESITGKE
                     VKNLITQILLLLIDVPGMRDTRFLNCPHSLLPLTSNAELLKHCLMAGKWSPKAEMIIL
                     AAERSEH"
     misc_feature    923..946
                     /note="polypurine tract 1"
     misc_feature    947..2206
                     /note="long terminal repeat"
     misc_feature    947..1862
                     /note="U3 region"
     misc_feature    1028..1044
                     /note="polypurine tract 2"
     regulatory      1833..1837
                     /note="put. TATA-box"
                     /regulatory_class="promoter"
     misc_feature    1863..2051
                     /note="R region"
     misc_feature    2027..2032
                     /note="pot. polyA signal"
     misc_feature    2052..2206
                     /note="U5 region"
BASE COUNT          691 a          406 c          484 g          625 t
ORIGIN      
        1 atcctgaagt tggaatttgg gtaaaatata aacccctcag aggaattgtt ggatctgctg
       61 tgtttattat gcataaacat caaagaaact gttctcttgt taaaccttct accagttgct
      121 cagaaggtcc aaaaccaaga cctaggcacg atcctgtcct tcgctgtgac atgtttgaaa
      181 agcatcacaa gcctcggcag aaacgaccca ggagacgatc catcgataat gagtcatgtg
      241 cttccagtag tgacaccatg gtcaatgagc catgatcact atgcaccaac cctctttgga
      301 atccttgacc gctactatca gggctacttg aagagtccag caacctacca aacttggaag
      361 ttcacatgtc aggtggaccc ttctgggaag aggtttatgg agactcaatt ttgggtcccc
      421 cctctgggtc aggtgaacat tcagttttat aagaattatc agattctaac ttgctgtcag
      481 gctgtagacc catttgctaa tatttttcat ggtactgatg aagaaatgtt tgacattgat
      541 tcaggtcctg atgtttggtg ttctccctct ttgtgtttca aggtaattta tgaaggggca
      601 atgggccaaa agcaagaaca aaaaacatgg ctgtgcagac taggacatgg tcatcgtatg
      661 ggagcatgcg attaccgtaa agtagatctg tatgcaatga gacaaggaaa agaaaaccct
      721 tatggagata ggggtgatgc agctttgcaa tatgcttatc aggttaaaag gggctgtaaa
      781 gcagggtgct tggcatcacc tgtacttaac tacaaagctt tgcagtttca tagaaccatt
      841 atggcagact tcaccaatcc taggattgga gaaggacatc ttgctcatgg ttaccaagca
      901 gctatggaag cttatggacc tcagagagga agtaacgagg agagggtgtg gtggaatgtc
      961 actagaaacc agggaaaaca aggaggagag tattacaggg aaggaggtga agaacctcat
     1021 tacccaaata ctcctgctcc tcatagacgt acctgggatg agagacacaa ggttcttaaa
     1081 ttgtcctcat tcgctactcc ctctgacatc caacgctgaa ctactaaagc attgccttat
     1141 ggctggaaag tggtcaccga aagcggaaat gattatacta gccgcagaaa gatcagaaca
     1201 ttgacagaga tgactcagga tgaaattaga aaaaggtggg aaagtggata ttgtgacccc
     1261 ttcattgact caggaagtga ctcagatgga cccttctaaa agccacagac agtaaaaatg
     1321 tgttagcact ttatacaata ttatatctgc ttaagctata gaagctttca catactcagt
     1381 agctgtttca caatcaacaa aacaatgatg atgtaatcat aaggaagtag tttaaaatag
     1441 gttaagtaag tttactgcag tagataatcc ctggggagga tctggctctg taagctggaa
     1501 cagcaatgtt ttcagttcca atcctctcaa aggagaacca gagggatgat gtgttagttc
     1561 aaatcccatt atcctcatgg ttcccttttc catagtttac tatattaatt taaggataag
     1621 gtataaggat taaggtatga ggtgtgtggc tcaacacgta gggtgacaag aaaatctact
     1681 gtaataggac acaacacctc taaagttgcc cgtgggaagg tgaagtgaga tcgaatcttt
     1741 ccttaacgca gacagctttt tatccactag ggataatgtt ttaaggaata ctatagtaat
     1801 agattgatag ttttaacaat gatagaaata gtatataagg atagtttcta gattgtacgg
     1861 gaggctcttc actactcgct gcgtcgagag tgtacgagac tctccaggtt tggtaagaaa
     1921 tattttatat tgttataatg ttactatgat ccattaacac tctgcttata gattgtaagg
     1981 gtgattgcaa tgctttctgc ataaaacttt ggttttcttg ttaatcaata aaccgacttg
     2041 attcgagaac caactcctat attattgtct cttttatact ttattaagta aaaggatttg
     2101 tatattagcc ttgctaaggg agacatctag tgatataagt gtgaactaca cttatcttaa
     2161 atgatgtaac tccttaggat aatcaatata caaaattcca tgacaa
//