LOCUS       X04676                   549 bp    DNA     linear   HUM 30-APR-1992
DEFINITION  Human hsp 70 gene 5' region for 70 kDa heat shock protein.
ACCESSION   X04676
VERSION     X04676.1
KEYWORDS    heat shock protein; heat shock protein 70; hsp70 gene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Drabent B., Genthe A., Benecke B.J.
  TITLE     In vitro transcription of a human hsp 70 heat shock gene by
            extracts prepared from heat-shocked and non-heat-shocked human
            cells
  JOURNAL   Nucleic Acids Res. 14(22), 8933-8948(1986).
   PUBMED   3786141
COMMENT     See <X04677> for hsp 70 gene 3' region.
            Another hsp 70 gene sequence is described in:
            Hunt,C. and Marimoto,R.(1985) Proc.Natl.Acad.Sci.USA 82,6455-6459
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /cell_line="HeLa"
                     /db_xref="taxon:9606"
     misc_feature    162..175
                     /note="heat shock element"
     regulatory      202..206
                     /note="CAAT-box (inverted)"
                     /regulatory_class="promoter"
     regulatory      241..246
                     /note="TATA-box"
                     /regulatory_class="promoter"
     precursor_RNA   271..>549
                     /note="primary transcript"
     CDS             484..>549
                     /note="hsp 70 (AA 1-22)"
                     /db_xref="GOA:P0DMV8"
                     /db_xref="HGNC:HGNC:5232"
                     /db_xref="InterPro:IPR013126"
                     /db_xref="InterPro:IPR018181"
                     /db_xref="InterPro:IPR029047"
                     /db_xref="InterPro:IPR029048"
                     /db_xref="PDB:1HJO"
                     /db_xref="PDB:1S3X"
                     /db_xref="PDB:1XQS"
                     /db_xref="PDB:2E88"
                     /db_xref="PDB:2E8A"
                     /db_xref="PDB:2LMG"
                     /db_xref="PDB:3A8Y"
                     /db_xref="PDB:3ATU"
                     /db_xref="PDB:3ATV"
                     /db_xref="PDB:3AY9"
                     /db_xref="PDB:3D2E"
                     /db_xref="PDB:3D2F"
                     /db_xref="PDB:3JXU"
                     /db_xref="PDB:3LOF"
                     /db_xref="PDB:3Q49"
                     /db_xref="PDB:4IO8"
                     /db_xref="PDB:4J8F"
                     /db_xref="PDB:4PO2"
                     /db_xref="PDB:4WV5"
                     /db_xref="PDB:4WV7"
                     /db_xref="PDB:5AQW"
                     /db_xref="PDB:5AQX"
                     /db_xref="PDB:5AQY"
                     /db_xref="PDB:5AQZ"
                     /db_xref="PDB:5AR0"
                     /db_xref="PDB:5BN8"
                     /db_xref="PDB:5BN9"
                     /db_xref="PDB:5BPL"
                     /db_xref="PDB:5BPM"
                     /db_xref="PDB:5BPN"
                     /db_xref="PDB:5GJJ"
                     /db_xref="PDB:5MKR"
                     /db_xref="PDB:5MKS"
                     /db_xref="PDB:5XI9"
                     /db_xref="PDB:5XIR"
                     /db_xref="PDB:6FHK"
                     /db_xref="PDB:6G3R"
                     /db_xref="PDB:6G3S"
                     /db_xref="UniProtKB/Swiss-Prot:P0DMV8"
                     /protein_id="CAA28381.1"
                     /translation="MAKAAAVGIDLGTTYSCVGVFQ"
BASE COUNT          110 a          174 c          167 g           98 t
ORIGIN      
        1 tggagaccaa cacccttccc accgccactc ccccttcctc tcagggtccc tgttccctcc
       61 agtgaatccc agaagactct ggagagttct gagcaggggg cggcactctg gcctctgatt
      121 ggtccaagga aggctggggg gcaggacggg aggcgaaaac cctggaatat tcccgacctg
      181 gcagcctcat cgagctcggt gattggctca gaagggaaaa ggcgggtctc cgtgacgact
      241 tataaaaccc caggggcaag cggtccggat aacggctagc ctgaggagct gctgcgacag
      301 tccactacct ttttcgagag tgactcccgt tgtcccaagg cttcccagag cgaacctgtg
      361 cggctgcagg caccggcgcg tcgagtttcc ggcgtccgga aggaccgagc tcttctcgcg
      421 gatccagtgt tccgtttcca gcccccaatc tcagagcgga gccgacagag agcagggaac
      481 cgcatggcca aagccgcggc agtcggcatc gacctgggca ccacctactc ctgcgtgggg
      541 gtgttccaa
//