LOCUS V00488 1138 bp DNA linear HUM 14-NOV-2006 DEFINITION Human alpha-globin germ line gene. ACCESSION V00488 VERSION V00488.1 KEYWORDS alpha-globin; germ line; globin. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1138) AUTHORS Liebhaber S.A., Goossens M.J., Kan Y.W. TITLE Cloning and complete nucleotide sequence of human 5'-alpha-globin gene JOURNAL Proc. Natl. Acad. Sci. U.S.A. 77(12), 7054-7058(1980). PUBMED 6452630 COMMENT KST HSA.ALPGLOBIN.GL [1138] FEATURES Location/Qualifiers source 1..1138 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" prim_transcript 98..929 exon 98..230 /number=1 CDS join(135..230,348..551,692..820) /product="alpha globin" /db_xref="GOA:P69905" /db_xref="HGNC:HGNC:4823" /db_xref="HGNC:HGNC:4824" /db_xref="InterPro:IPR000971" /db_xref="InterPro:IPR002338" /db_xref="InterPro:IPR002339" /db_xref="InterPro:IPR009050" /db_xref="InterPro:IPR012292" /db_xref="PDB:1A00" /db_xref="PDB:1A01" /db_xref="PDB:1A0U" /db_xref="PDB:1A0Z" /db_xref="PDB:1A3N" /db_xref="PDB:1A3O" /db_xref="PDB:1A9W" /db_xref="PDB:1ABW" /db_xref="PDB:1ABY" /db_xref="PDB:1AJ9" /db_xref="PDB:1B86" /db_xref="PDB:1BAB" /db_xref="PDB:1BBB" /db_xref="PDB:1BIJ" /db_xref="PDB:1BUW" /db_xref="PDB:1BZ0" /db_xref="PDB:1BZ1" /db_xref="PDB:1BZZ" /db_xref="PDB:1C7B" /db_xref="PDB:1C7C" /db_xref="PDB:1C7D" /db_xref="PDB:1CLS" /db_xref="PDB:1CMY" /db_xref="PDB:1COH" /db_xref="PDB:1DKE" /db_xref="PDB:1DXT" /db_xref="PDB:1DXU" /db_xref="PDB:1DXV" /db_xref="PDB:1FDH" /db_xref="PDB:1FN3" /db_xref="PDB:1G9V" /db_xref="PDB:1GBU" /db_xref="PDB:1GBV" /db_xref="PDB:1GLI" /db_xref="PDB:1GZX" /db_xref="PDB:1HAB" /db_xref="PDB:1HAC" /db_xref="PDB:1HBA" /db_xref="PDB:1HBB" /db_xref="PDB:1HBS" /db_xref="PDB:1HCO" /db_xref="PDB:1HDB" /db_xref="PDB:1HGA" /db_xref="PDB:1HGB" /db_xref="PDB:1HGC" /db_xref="PDB:1HHO" /db_xref="PDB:1IRD" /db_xref="PDB:1J3Y" /db_xref="PDB:1J3Z" /db_xref="PDB:1J40" /db_xref="PDB:1J41" /db_xref="PDB:1J7S" /db_xref="PDB:1J7W" /db_xref="PDB:1J7Y" /db_xref="PDB:1JY7" /db_xref="PDB:1K0Y" /db_xref="PDB:1K1K" /db_xref="PDB:1KD2" /db_xref="PDB:1LFL" /db_xref="PDB:1LFQ" /db_xref="PDB:1LFT" /db_xref="PDB:1LFV" /db_xref="PDB:1LFY" /db_xref="PDB:1LFZ" /db_xref="PDB:1LJW" /db_xref="PDB:1M9P" /db_xref="PDB:1MKO" /db_xref="PDB:1NEJ" /db_xref="PDB:1NIH" /db_xref="PDB:1NQP" /db_xref="PDB:1O1I" /db_xref="PDB:1O1J" /db_xref="PDB:1O1K" /db_xref="PDB:1O1L" /db_xref="PDB:1O1M" /db_xref="PDB:1O1N" /db_xref="PDB:1O1O" /db_xref="PDB:1O1P" /db_xref="PDB:1QI8" /db_xref="PDB:1QSH" /db_xref="PDB:1QSI" /db_xref="PDB:1QXD" /db_xref="PDB:1QXE" /db_xref="PDB:1R1X" /db_xref="PDB:1R1Y" /db_xref="PDB:1RPS" /db_xref="PDB:1RQ3" /db_xref="PDB:1RQ4" /db_xref="PDB:1RQA" /db_xref="PDB:1RVW" /db_xref="PDB:1SDK" /db_xref="PDB:1SDL" /db_xref="PDB:1SHR" /db_xref="PDB:1SI4" /db_xref="PDB:1THB" /db_xref="PDB:1UIW" /db_xref="PDB:1VWT" /db_xref="PDB:1XXT" /db_xref="PDB:1XY0" /db_xref="PDB:1XYE" /db_xref="PDB:1XZ2" /db_xref="PDB:1XZ4" /db_xref="PDB:1XZ5" /db_xref="PDB:1XZ7" /db_xref="PDB:1XZU" /db_xref="PDB:1XZV" /db_xref="PDB:1Y01" /db_xref="PDB:1Y09" /db_xref="PDB:1Y0A" /db_xref="PDB:1Y0C" /db_xref="PDB:1Y0D" /db_xref="PDB:1Y0T" /db_xref="PDB:1Y0W" /db_xref="PDB:1Y22" /db_xref="PDB:1Y2Z" /db_xref="PDB:1Y31" /db_xref="PDB:1Y35" /db_xref="PDB:1Y45" /db_xref="PDB:1Y46" /db_xref="PDB:1Y4B" /db_xref="PDB:1Y4F" /db_xref="PDB:1Y4G" /db_xref="PDB:1Y4P" /db_xref="PDB:1Y4Q" /db_xref="PDB:1Y4R" /db_xref="PDB:1Y4V" /db_xref="PDB:1Y5F" /db_xref="PDB:1Y5J" /db_xref="PDB:1Y5K" /db_xref="PDB:1Y7C" /db_xref="PDB:1Y7D" /db_xref="PDB:1Y7G" /db_xref="PDB:1Y7Z" /db_xref="PDB:1Y83" /db_xref="PDB:1Y85" /db_xref="PDB:1Y8W" /db_xref="PDB:1YDZ" /db_xref="PDB:1YE0" /db_xref="PDB:1YE1" /db_xref="PDB:1YE2" /db_xref="PDB:1YEN" /db_xref="PDB:1YEO" /db_xref="PDB:1YEQ" /db_xref="PDB:1YEU" /db_xref="PDB:1YEV" /db_xref="PDB:1YFF" /db_xref="PDB:1YG5" /db_xref="PDB:1YGD" /db_xref="PDB:1YGF" /db_xref="PDB:1YH9" /db_xref="PDB:1YHE" /db_xref="PDB:1YHR" /db_xref="PDB:1YIE" /db_xref="PDB:1YIH" /db_xref="PDB:1YVQ" /db_xref="PDB:1YVT" /db_xref="PDB:1YZI" /db_xref="PDB:1Z8U" /db_xref="PDB:2D5Z" /db_xref="PDB:2D60" /db_xref="PDB:2DN1" /db_xref="PDB:2DN2" /db_xref="PDB:2DN3" /db_xref="PDB:2DXM" /db_xref="PDB:2H35" /db_xref="PDB:2HBC" /db_xref="PDB:2HBD" /db_xref="PDB:2HBE" /db_xref="PDB:2HBF" /db_xref="PDB:2HBS" /db_xref="PDB:2HCO" /db_xref="PDB:2HHB" /db_xref="PDB:2HHD" /db_xref="PDB:2HHE" /db_xref="PDB:2M6Z" /db_xref="PDB:2W6V" /db_xref="PDB:2W72" /db_xref="PDB:2YRS" /db_xref="PDB:3B75" /db_xref="PDB:3D17" /db_xref="PDB:3D7O" /db_xref="PDB:3DUT" /db_xref="PDB:3HHB" /db_xref="PDB:3HXN" /db_xref="PDB:3IA3" /db_xref="PDB:3IC0" /db_xref="PDB:3IC2" /db_xref="PDB:3KMF" /db_xref="PDB:3NL7" /db_xref="PDB:3NMM" /db_xref="PDB:3ODQ" /db_xref="PDB:3ONZ" /db_xref="PDB:3OO4" /db_xref="PDB:3OO5" /db_xref="PDB:3OVU" /db_xref="PDB:3P5Q" /db_xref="PDB:3QJB" /db_xref="PDB:3QJC" /db_xref="PDB:3QJD" /db_xref="PDB:3QJE" /db_xref="PDB:3R5I" /db_xref="PDB:3S48" /db_xref="PDB:3S65" /db_xref="PDB:3S66" /db_xref="PDB:3SZK" /db_xref="PDB:3WCP" /db_xref="PDB:3WHM" /db_xref="PDB:4FC3" /db_xref="PDB:4HHB" /db_xref="PDB:4IJ2" /db_xref="PDB:4L7Y" /db_xref="PDB:4M4A" /db_xref="PDB:4M4B" /db_xref="PDB:4MQC" /db_xref="PDB:4MQG" /db_xref="PDB:4MQH" /db_xref="PDB:4MQI" /db_xref="PDB:4MQJ" /db_xref="PDB:4MQK" /db_xref="PDB:4N7N" /db_xref="PDB:4N7O" /db_xref="PDB:4N7P" /db_xref="PDB:4N8T" /db_xref="PDB:4NI0" /db_xref="PDB:4NI1" /db_xref="PDB:4ROL" /db_xref="PDB:4ROM" /db_xref="PDB:4WJG" /db_xref="PDB:4X0L" /db_xref="PDB:4XS0" /db_xref="PDB:5E29" /db_xref="PDB:5E6E" /db_xref="PDB:5E83" /db_xref="PDB:5EE4" /db_xref="PDB:5HU6" /db_xref="PDB:5HY8" /db_xref="PDB:5JDO" /db_xref="PDB:5KDQ" /db_xref="PDB:5KSI" /db_xref="PDB:5KSJ" /db_xref="PDB:5NI1" /db_xref="PDB:5SW7" /db_xref="PDB:5U3I" /db_xref="PDB:5UCU" /db_xref="PDB:5UFJ" /db_xref="PDB:5URC" /db_xref="PDB:5VMM" /db_xref="PDB:5WOG" /db_xref="PDB:5WOH" /db_xref="PDB:5X2R" /db_xref="PDB:5X2S" /db_xref="PDB:5X2T" /db_xref="PDB:5X2U" /db_xref="PDB:6BB5" /db_xref="PDB:6BNR" /db_xref="PDB:6BWP" /db_xref="PDB:6BWU" /db_xref="PDB:6DI4" /db_xref="PDB:6HAL" /db_xref="PDB:6HBW" /db_xref="PDB:6NBC" /db_xref="PDB:6NBD" /db_xref="UniProtKB/Swiss-Prot:P69905" /protein_id="CAA23748.1" /translation="MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYF PHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLL SHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR" exon 348..551 /number=2 exon 692..929 /number=3 BASE COUNT 183 a 412 c 350 g 193 t ORIGIN 1 aggccgcgcc ccgggctccg cgccagccaa tgagcgccgc ccggccgggc gtgcccccgc 61 gccccaagca taaaccctgg cgcgctcgcg gcccggcact cttctggtcc ccacagactc 121 agagagaacc caccatggtg ctgtctcctg ccgacaagac caacgtcaag gccgcctggg 181 gtaaggtcgg cgcgcacgct ggcgagtatg gtgcggaggc cctggagagg tgaggctccc 241 tcccctgctc cgacccgggc tcctcgcccg cccggaccca caggccaccc tcaaccgtcc 301 tggccccgga cccaaacccc acccctcact ctgcttctcc ccgcaggatg ttcctgtcct 361 tccccaccac caagacctac ttcccgcact tcgacctgag ccacggctct gcccaagtta 421 agggccacgg caagaaggtg gccgacgcgc tgaccaacgc cgtggcgcac gtggacgaca 481 tgcccaacgc gctgtccgcc ctgagcgacc tgcacgcgca caagcttcgg gtggacccgg 541 tcaacttcaa ggtgagcggc gggccgggag cgatctgggt cgaggggcga gatggcgcct 601 tcctctcagg gcagaggatc acgcgggttg cgggaggtgt agcgcaggcg gcggcgcggc 661 ttgggccgca ctgaccctct tctctgcaca gctcctaagc cactgcctgc tggtgaccct 721 ggccgcccac ctccccgccg agttcacccc tgcggtgcac gcttccctgg acaagttcct 781 ggcttctgtg agcaccgtgc tgacctccaa ataccgttaa gctggagcct cggtagccgt 841 tcctcctgcc cgctgggcct cccaacgggc cctcctcccc tccttgcacc ggcccttcct 901 ggtctttgaa taaagtctga gtgggcggca gcctgtgtgt gcctgggttc tctctgtccc 961 ggaatgtgcc aacaatggag gtgtttacct gtctcagacc aaggacctct ctgcagctgc 1021 atggggctgg ggagggagaa ctgcagggag tatgggaggg gaagctgagg tgggcctgct 1081 caagagaagg tgctgaacca tcccctgtcc tgagaggtgc cagcctgcag gcagtggc //