LOCUS       MTU67924                1500 bp    DNA     linear   BCT 18-JUL-2000
DEFINITION  Mycobacterium tuberculosis beta-lactamase (blaA) gene, complete
            cds.
ACCESSION   U67924
VERSION     U67924.1
KEYWORDS    .
SOURCE      Mycobacterium tuberculosis H37Ra
  ORGANISM  Mycobacterium tuberculosis H37Ra
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis
            complex.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Hackbarth,C.J., Unsal,I. and Chambers,H.F.
  TITLE     Cloning and sequence analysis of a class A beta-lactamase from
            Mycobacterium tuberculosis H37Ra
  JOURNAL   Antimicrob. Agents Chemother. 41 (5), 1182-1185 (1997)
   PUBMED   9145897
REFERENCE   2  (bases 1 to 1500)
  AUTHORS   Hackbarth,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-1996) Division of Infectious Diseases, San
            Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA
            94110, USA
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Mycobacterium tuberculosis H37Ra"
                     /mol_type="genomic DNA"
                     /strain="H37Ra"
                     /db_xref="taxon:419947"
     gene            277..1200
                     /gene="blaA"
     CDS             277..1200
                     /gene="blaA"
                     /note="Class A"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase"
                     /protein_id="AAB07556.1"
                     /translation="MRNRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADL
                     ADRFAELERRYDARLGVYVPATGTTAAIEYRADERFAFCSTFKAPLVAAVLHQNPLTH
                     LDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGPGGG
                     TAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPD
                     KRALLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVA
                     VMSDRAGGGYDAEPREALLAEAATCVAGVLA"
BASE COUNT          271 a          480 c          489 g          260 t
ORIGIN      
        1 aagatagggc gacgaaccgc ccacaacgtc tttgctgggt ggcttttgat aaacgccttc
       61 aaggggcccg cccgtttccc cttggccgcc gacaaggcga gtgcggaaac ggccttcgtc
      121 gtcgacttgc cgtcgcggtc atgggcataa accatagccc ggcaggtccg gtcagtctac
      181 gaccggtcgt cgtagatccc gccgccgagc agccggggga gcgcggcgtc gaatgcgctt
      241 tggcgcctgc catctgcgcg cgtgtgatac tacggcatgc gcaacagagg attcggtcgt
      301 cgcgaactgc tggtagcgat ggcaatgctg gtttccgtga cggggtgtgc acggcatgcg
      361 agcggggccc gtccggcatc gacaaccttg ccggccggag cggatctggc ggatcgcttc
      421 gccgagctgg agcgcagata cgatgcccgg cttggggtgt atgtgcccgc caccggcacc
      481 accgccgcga tcgaataccg cgccgatgag cggttcgcat tctgctccac gttcaaggcg
      541 ccgctcgtgg cggcggtgct gcaccaaaac ccgctcacgc atctggacaa actgatcacc
      601 tacaccagtg acgacattcg gtcgatctcc ccggtggccc aacaacacgt tcagaccggg
      661 atgacgatcg ggcagctttg cgatgcggcg atacgctata gcgacggcac cgccgccaac
      721 ctgttgctgg ccgatcttgg cggtcccggg ggcggcaccg cggcatttac cggctacctc
      781 cgcagcttgg gtgacaccgt gagccggttg gacgccgagg aaccggagtt gaaccgcgat
      841 ccgcccgggg acgaacggga taccacaaca ccgcacgcca tcgccctggt gttgcagcag
      901 cttgttctcg gcaacgcgtt gccgcccgac aagcgggcac tgctcaccga ttggatggcg
      961 cgcaacacca ccggagccaa gcggatccga gcgggctttc ccgccgattg gaaggtgatc
     1021 gacaagaccg ggaccggtga ctacggacga gcaaacgaca tcgcggtcgt gtggtcaccg
     1081 accggcgtgc cctacgtggt ggccgtcatg tccgatcgtg ccggcggcgg gtatgacgcc
     1141 gagccccgtg aggcgctgct cgccgaggcg gcgacgtgcg ttgccggtgt gcttgcatag
     1201 gctcgtggga ccgaagtgac cgacgatcat ccgcgcgccg acattgtgtc ccggcagtac
     1261 caccggtggt tgtacccgca cccgatcgcc gatcttgagg cgtggaccac agcgaattgg
     1321 gaatggttcg acccggtgca ctcccaccgg atattatggc cggaccggca ataccggccc
     1381 gatctggata ttctgatcgc cggttgcgga accaaccagg cggcgatttt cgcattcacc
     1441 aatcgtgcgg cgaaagtagt ggcgatatca gtcgaccggc actggaccat cagcaatatc
//