LOCUS       MKU41058                1171 bp    DNA     linear   BCT 16-APR-1996
DEFINITION  Methanopyrus kandleri reverse gyrase A subunit (rgyA) gene,
            complete cds.
ACCESSION   U41058
VERSION     U41058.1
KEYWORDS    .
SOURCE      Methanopyrus kandleri
  ORGANISM  Methanopyrus kandleri
            Archaea; Euryarchaeota; Methanomada group; Methanopyri;
            Methanopyrales; Methanopyraceae; Methanopyrus.
REFERENCE   1  (bases 1 to 1171)
  AUTHORS   Krah,R., Kozyavkin,S.A., Slesarev,A.I. and Gellert,M.
  TITLE     A two-subunit type I DNA topoisomerase (reverse gyrase) from an
            extreme hyperthermophile
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 93 (1), 106-110 (1996)
   PUBMED   8552584
REFERENCE   2  (bases 1 to 1171)
  AUTHORS   Krah,R., Kozyavkin,S.A., Slesarev,A.I. and Gellert,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-NOV-1995) Regis Krah, National Institute of Diabetes
            and Digestive and Kidney Diseases, National Institutes of Health,
            9000 Rockville Pike, Bethesda, MD 20892, USA
FEATURES             Location/Qualifiers
     source          1..1171
                     /organism="Methanopyrus kandleri"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:2320"
     gene            40..1116
                     /gene="rgyA"
     CDS             40..1116
                     /gene="rgyA"
                     /note="topoisomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="reverse gyrase A subunit"
                     /protein_id="AAA96962.1"
                     /translation="MNATLRIRNRPVAESTYTSLRGAKAEVVRVEREEREIHPKPPFE
                     TGTMLQAATRRLRLSSERVMQLAQDLFEGGLITYHRTDSTRVSEEGKRVRRDYIRANF
                     DPEDYNPRTWEPEAEHVEGAHECIRPTRPADAEELRTMVREGAIQTTVTLTSHHLRLY
                     DLVFRRFVASQMKPAKVLYQEAVLEVEVKGVPVAELELSGVLEIVEPGFTKVLTEYDL
                     PAYGIRETPELEEGDRLEIGAVEVLERHEEYPYDQSELVEDMRERGLGRPSTYAQIVE
                     KLFRRGYVYEVPQRRWIFPTTRGEAVYEYLSTHYERFVSEETTRDLEERMDAVALGKA
                     EYQEEMEKLYLELERVVEMPDPEP"
BASE COUNT          272 a          329 c          370 g          200 t
ORIGIN      
        1 cggcgctcgc cctaaccctg cgagaccggg ggatcgtaat tgaatgcgac actccggatc
       61 cggaacagac ctgtcgccga gtcgacctac acttcgctga ggggagcgaa ggctgaggtc
      121 gtccgagttg agcgagagga gcgtgaaata caccctaaac cacctttcga aaccggaacc
      181 atgcttcagg cggctacccg acgacttcga ctgtcgtccg agcgtgtcat gcagctggcc
      241 caggacctgt tcgagggagg tctcatcaca taccaccgga ccgactctac cagggtctcg
      301 gaggagggca agcgcgtacg ccgggactac atccgggcta acttcgaccc cgaagactac
      361 aatccgagga cctgggaacc cgaggccgag cacgtcgaag gtgctcacga gtgtataaga
      421 cccaccagac cggccgacgc cgaggagcta cggacgatgg ttcgtgaggg agcgattcag
      481 accaccgtca cgctgacttc tcaccattta cgtctttacg atctcgtctt ccgacgtttc
      541 gtagccagcc agatgaagcc cgcgaaggtc ctctaccagg aggccgtgct ggaggtcgaa
      601 gtcaaaggag tgcccgtcgc ggagctcgaa ctcagcggag ttttggagat cgtcgagccg
      661 ggcttcacta aggtcctaac ggagtacgac ctgccggcgt acggcatccg ggagaccccg
      721 gaactggagg agggagatcg gctcgaaata ggcgccgtgg aggtgctgga acggcatgaa
      781 gagtacccgt acgatcaatc ggagttggtt gaagacatgc gagagcgggg actcggccgt
      841 cctagcacct acgcgcagat agtcgagaag ctgttccggc gtgggtacgt gtacgaggta
      901 ccgcaacgga ggtggatatt cccgacgacc cgtggtgagg ccgtctacga gtacctcagt
      961 acccactacg agcggttcgt atcggaggaa actacgagag acctggagga acgcatggac
     1021 gccgtagcgc tcggtaaggc cgagtatcaa gaggagatgg aaaaactcta cctagagctc
     1081 gaaagggtcg tcgagatgcc tgacccggaa ccgtgatcgc cgatcacgtg cggaggtgag
     1141 ccgccataag acgcaaagta tacttctttt c
//