LOCUS       BTU34247                1506 bp    mRNA    linear   MAM 08-NOV-1995
DEFINITION  Bovine plasma PAF acetylhydrolase mRNA, complete cds.
ACCESSION   U34247
VERSION     U34247.1
KEYWORDS    .
SOURCE      Bos taurus (domestic cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Tjoelker,L.W., Wilder,C., Eberhardt,C., Stafforini,D.M.,
            Dietsch,G., Schimpf,B., Hooper,S., Le Trong,H., Cousens,L.S.,
            Zimmerman,G.A., Yamada,Y., McIntyre,T.M., Prescott,S.M. and
            Gray,P.W.
  TITLE     Anti-inflammatory properties of a platelet-activating factor
            acetylhydrolase
  JOURNAL   Nature 374 (6522), 549-553 (1995)
   PUBMED   7700381
REFERENCE   2  (bases 1 to 1506)
  AUTHORS   Tjoelker,L.W., Eberhardt,C., Unger,J., Trong,H.L., Zimmerman,G.A.,
            McIntyre,T.M., Stafforini,D.M., Prescott,S.M. and Gray,P.W.
  TITLE     Plasma platelet-activating factor acetylhydrolase is a secreted
            phospholipase A2 with a catalytic triad
  JOURNAL   J. Biol. Chem. 270 (43), 25481-25487 (1995)
   PUBMED   7592717
REFERENCE   3  (bases 1 to 1506)
  AUTHORS   Tjoelker,L.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-AUG-1995) Larry W. Tjoelker, ICOS Corporation, 22021
            20th Ave S.E., Bothell, WA 98021, USA
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Bos taurus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9913"
                     /note="Spleen"
     CDS             62..1396
                     /codon_start=1
                     /product="plasma PAF acetylhydrolase"
                     /protein_id="AAC48483.1"
                     /translation="MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQA
                     LMAAANIGQSKIPRGNGSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKE
                     YFLGLSKFLGTHWLVGKIMGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIY
                     SAIGIDLASHGFIVAAVEHRDGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPL
                     RNEQLRQRAKECSQALSLILDIDHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFG
                     GATVIQTLSEDQRFRCGIALDAWMFPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKK
                     CFLPDRERKMITIRGSVHQNFVDFTFATSKIIGYLFTLKGDIDSNVAISLSNKASLAF
                     LQKHLGLQKDFDQWDSLVEGEDHNLIPGTNINTTNHQAILQNSTGIERPNLD"
     polyA_site      1506
                     /note="26 A nucleotides"
BASE COUNT          435 a          312 c          320 g          439 t
ORIGIN      
        1 ccgcgagcag ttcaccgcgg cgtccggaag gttaagctga aacggcagct cagcttcgga
       61 gatgttaccg tccaaattgc atgcgctttt ctgcctctgc acctgccttg cactggttta
      121 tccttttgac tggcaagacc tgaatccagt tgcctatatt gaatcaccag catgggtcag
      181 taagatacaa gctctgatgg ctgctgcaaa cattggtcaa tctaaaatcc ccagaggaaa
      241 tggatcttat tccgtcggtt gtacagactt gatgtttgat tacactaata agggcacctt
      301 cttgcgtttg tattatccat ctcaagatga tgatcactcc gacacccttt ggatcccaaa
      361 caaagaatat tttttgggtc ttagtaaatt tcttggaaca cactggcttg tgggcaaaat
      421 tatgggctta ttcttcggtt caatgacaac tcctgcagcc tggaatgcac atctgaggac
      481 tggggaaaaa tacccactaa ttattttttc tcatggtctt ggagcattca ggacgattta
      541 ttctgctatt ggcattgatc tggcatccca cgggtttata gttgctgctg tagaacacag
      601 ggatggctct gcatcctcga catactattt caaggaccag tctgctgtag aaataggcaa
      661 caagtcttgg ctctatctca gaaccctgaa gcgaggagag gaggagtttc ctttacgaaa
      721 tgagcagtta cggcaacgag caaaggaatg ttctcaagct ctcagtttga ttctggacat
      781 tgatcacggg aggccagtga cgaatgtact agatttagag tttgatgtgg aacagctgaa
      841 ggactctatt gatagggata aaatagccat tattggacat tcttttggtg gagccacagt
      901 tattcagact cttagtgaag accagagatt caggtgtggc attgctctgg atgcatggat
      961 gtttcccgtg ggtgatgaag tatattccag aattcctcaa cccctctttt ttatcaactc
     1021 ggaacgattc caataccctt ctaatatcat aagaatgaaa aaatgcttct tacctgatag
     1081 agaacgaaaa atgattacaa tcaggggttc ggtccatcag aattttgttg acttcacttt
     1141 tgccactagc aaaataattg gctacctatt cacactgaaa ggagacatcg attccaatgt
     1201 agccatcagc cttagcaaca aagcttcctt agcgttctta caaaaacatt taggacttca
     1261 gaaagatttt gatcagtggg attctttagt tgaaggcgaa gatcacaatc ttattccagg
     1321 gaccaacatt aacacaacca accaccaagc cattctgcag aactccacag gaatagagag
     1381 accaaattta gattaaaaga gctttttaaa aagttttgtt tacgaacttg tctaaaagtg
     1441 tgtgtgtgta tgatttaaat gtattttctc aaatagctca tattaaaaaa tgtaggctat
     1501 agcaca
//