LOCUS       MMU12961                1528 bp    mRNA    linear   ROD 31-OCT-1995
DEFINITION  Mus musculus NAD(P)H:menadione oxidoreductase (Nmo1) mRNA, complete
            cds.
ACCESSION   U12961
VERSION     U12961.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1528)
  AUTHORS   Vasiliou,V., Theurer,M.J., Puga,A., Reuter,S.F. and Nebert,D.W.
  TITLE     Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA
            sequence and genetic differences in mRNA levels
  JOURNAL   Pharmacogenetics 4 (6), 341-348 (1994)
   PUBMED   7704040
REFERENCE   2  (sites)
  AUTHORS   Petersen,D.D., Gonzalez,F.J., Rapic,V., Kozak,C.A., Lee,J.Y.,
            Jones,J.E. and Nebert,D.W.
  TITLE     Marked increases in hepatic NAD(P)H:oxidoreductase gene
            transcription and mRNA levels correlated with a mouse chromosome 7
            deletion
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 86 (17), 6699-6703 (1989)
   PUBMED   2505256
REFERENCE   3  (bases 1 to 1528)
  AUTHORS   Vasiliou,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-1994) Vasilis Vasiliou, Environmental Health,
            University of Cincinnati Medical Center, 3223 Eden Avenue,
            Cincinnati, OH 45267-0056, USA
FEATURES             Location/Qualifiers
     source          1..1528
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="B6/CBAF1J; C57 black 6 X CBA"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /tissue_type="liver"
                     /clone_lib="lambda Zap (Stratagene)"
     gene            1..1528
                     /gene="Nmo1"
     CDS             109..933
                     /gene="Nmo1"
                     /EC_number="1.6.5.2"
                     /function="two-electron reduction of quinones"
                     /standard_name="NAD(P)H:menadione (quinone acceptor)
                     oxidoreductase"
                     /codon_start=1
                     /product="NAD(P)H:menadione oxidoreductase"
                     /protein_id="AAA80184.1"
                     /translation="MAARRALIVLAHSEKTSFNYAMKEAAVEALKKRGWEVLESDLYA
                     MNFNPIISRNDITGELKDSKNFQYPSESSLAYKEGRLSPDIVAEHKKLEAADLVIFQF
                     PLQWFGVPAILKGWFERVLVAGFAYTYAAMYDNGPFQNKKTLLSITTGGSGSMYSLQG
                     VHGDMNVILWPIQSGILRFCGFQVLEPQLVYSIGHTPPDARMQILEGWKKRLETVWEE
                     TPLYFAPSSLFDLNFQAGFLMKKEVQEEQKKNKFGLSVGHHLGKSIPADNQIKARK"
     regulatory      1506..1511
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nmo1"
BASE COUNT          393 a          358 c          355 g          422 t
ORIGIN      
        1 ctgagccagc cctaaggatc tctccgaaga gctttagggt cgtcttggca accagctgct
       61 cagccaatca gcgttcggta ttacgatcct ccctcaacat ctcgagccat ggcggcgaga
      121 agagccctga ttgtactggc ccattcagag aagacatcat tcaactacgc catgaaggag
      181 gctgctgtag aggctctgaa gaagagagga tgggaggtac tcgaatctga cctctatgct
      241 atgaacttca accccatcat ttccagaaat gacatcacag gtgagctgaa ggactcgaag
      301 aactttcagt atccttccga gtcatctcta gcatataagg aaggacgcct gagcccagat
      361 attgtggccg aacacaagaa gctggaagct gcagacctgg tgatatttca gttcccattg
      421 cagtggtttg gggtgccagc cattctgaaa ggctggtttg agagagtgct cgtagcagga
      481 tttgcctaca catatgctgc catgtacgac aacggtcctt tccagaataa gaagaccttg
      541 ctttctatca ccactggggg tagcggctcc atgtactctc ttcagggtgt ccacggggac
      601 atgaacgtca ttctctggcc gattcagagt ggcatcctgc gtttctgtgg cttccaggtc
      661 ttagaacctc aactggttta cagcattggc cacactccac cagatgcccg catgcagatc
      721 ctggaaggat ggaagaaacg tctggaaacc gtctgggagg agaccccact ctattttgct
      781 ccaagcagcc tgtttgacct aaactttcag gcaggattct taatgaaaaa ggaagttcaa
      841 gaggagcaga agaagaacaa gtttggcctc tctgtgggcc atcacctggg caagtccatt
      901 ccagctgaca accagatcaa agctagaaaa taaggatttt tttcctaaca tatagttaga
      961 cgcagctttc tttttcccca gcttgtctga cttgctttca tttttttcct ttgctccacg
     1021 aggatgggaa aaggagtaag tttgcttcat gctttttttt ttttttagta gttctgccat
     1081 aacaacaaaa tgaatgaagt cagattagga gcctcagggc aaggtgcaga agcgagctgg
     1141 aaatactctt ctaggtcatt tatgcaatat tcgccatttt cttcgggcta gtcccagtta
     1201 gatggcatcc agtcctccat tcaagattcg ttgtctataa ttacctctct gtggtttagg
     1261 gcagaaggga attgctcaaa gtaaacaatg gccgagggac taacttgttt agcagttagc
     1321 agttagctaa agcctgttta tgatacatcc tggtttcaat tactgtgcag tgactgacat
     1381 ggcgcccagg gggttggctc tccagctctt ttctgtcttg tacacagcac acccaggtcc
     1441 tgggaaagga attttaaaac agatctccgt ctcattcttt ctatttcttt ttttttttta
     1501 atcgaaataa atgaatacat cacacatc
//