LOCUS       MK720823                 458 bp    mRNA    linear   MAM 11-AUG-2019
DEFINITION  Canis lupus laniger isolate Tw hemoglobin subunit beta/delta hybrid
            mRNA, complete cds.
ACCESSION   MK720823
VERSION     MK720823.1
KEYWORDS    .
SOURCE      Canis lupus laniger (Tibetan wolf)
  ORGANISM  Canis lupus laniger
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
            Canis.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Signore,A.V., Yang,Y.Z., Yang,Q.Y., Qin,G., Moriyama,H., Ge,R.L.
            and Storz,J.F.
  TITLE     Adaptive changes in hemoglobin function in high-altitude Tibetan
            canids were derived via gene conversion and introgression
  JOURNAL   Mol. Biol. Evol. (2019) In press
   PUBMED   31362306
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 458)
  AUTHORS   Signore,A.V., Yang,Y.-Z., Yang,Q.-Y., Qin,G., Ge,R.-L. and
            Storz,J.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAR-2019) School Biological Sciences, University of
            Nebraska, 1104 T Street, Lincoln, NE 68588, USA
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Canis lupus laniger"
                     /mol_type="mRNA"
                     /isolate="Tw"
                     /sub_species="laniger"
                     /db_xref="taxon:554455"
                     /tissue_type="blood"
     CDS             14..457
                     /note="HBB/D"
                     /codon_start=1
                     /product="hemoglobin subunit beta/delta hybrid"
                     /protein_id="QDY81622.1"
                     /translation="MVHLTAEEKSLVSSMWGKVNVDEVGGEALGRLLIVYPWTQRFFD
                     SFGDLSTPDAVMSNAKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPE
                     NFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH"
BASE COUNT          104 a          113 c          133 g          108 t
ORIGIN      
        1 acaaacagac accatggtgc atctgactgc tgaagagaag agtcttgtct ccagcatgtg
       61 gggcaaggtg aatgtggacg aagttggcgg tgaggccctg ggcaggctgc tgattgtcta
      121 cccctggact cagaggttct ttgactcctt tggggacctg tccactcctg atgctgttat
      181 gagcaatgct aaagtgaagg cccatggcaa gaaggtgctg aactccttta gtgatggcct
      241 gaaaaacctg gacaacctca agggcacctt tgctaagctc agtgagcttc actgtgacaa
      301 gctgcacgtg gatcccgaga acttcaagct cctgggcaac gtgcttgtgt gtgtgctggc
      361 tcaccacttt ggcaaagaat tcacccctca ggtgcaggct gcctatcaga aggtggtggc
      421 tggtgtggcc aatgccctgg ctcacaagta ccattgag
//