LOCUS       ASNALLIA                 678 bp    DNA     linear   PLN 11-SEP-1996
DEFINITION  Aspergillus fumigatus major allergen I (Aspf1) gene, complete cds.
ACCESSION   M83781
VERSION     M83781.1
KEYWORDS    cytotoxin; major allergen I; mitogillin.
SOURCE      Aspergillus fumigatus
  ORGANISM  Aspergillus fumigatus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Arruda,L.K., Platts-Mills,T.A., Fox,J.W. and Chapman,M.D.
  TITLE     Aspergillus fumigatus allergen I, a major IgE-binding protein, is a
            member of the mitogillin family of cytotoxins
  JOURNAL   J. Exp. Med. 172 (5), 1529-1532 (1990)
   PUBMED   2230656
REFERENCE   2  (bases 1 to 678)
  AUTHORS   Arruda,L.K., Mann,B.J. and Chapman,M.D.
  TITLE     Selective expression of a major allergen and cytotoxin, Asp f I, in
            Aspergillus fumigatus. Implications for the immunopathogenesis of
            Aspergillus-related diseases
  JOURNAL   J. Immunol. 149 (10), 3354-3359 (1992)
   PUBMED   1431110
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Aspergillus fumigatus"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:746128"
                     /dev_stage="spore"
     gene            60..642
                     /gene="Aspf1"
     CDS             join(60..143,196..642)
                     /gene="Aspf1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="sequence is identical to the 18 kDa sequence of
                     Lamy et al. (X58278)"
                     /citation=[1]
                     /codon_start=1
                     /product="major allergen I"
                     /protein_id="AAB07779.1"
                     /translation="MVAIKNLFLLAATAVSVLAAPSPLDARATWTCINQQLNPKTNKW
                     EDKRLLYNQAKAESNSHHAPLSDGKTGSSYPHWFTNGYDGNGKLIKGRTPIKFGKADC
                     DRPPKHSQNGMGKDDHYLLEFPTFPDGHDYKFDSKKPKEDPGPARVIYTYPNKVFCGI
                     VAHQRGNQGDLRLCSH"
     sig_peptide     60..140
                     /gene="Aspf1"
                     /note="putative"
     mat_peptide     join(141..143,196..639)
                     /gene="Aspf1"
                     /product="major allergen I"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="sequence is identical to the 18 kDa sequence of
                     Lamy et al. (X58278)"
                     /citation=[1]
     exon            60..143
                     /gene="Aspf1"
                     /number=1
     intron          144..195
                     /gene="Aspf1"
                     /number=1
     exon            196..642
                     /gene="Aspf1"
                     /number=2
BASE COUNT          181 a          195 c          165 g          137 t
ORIGIN      
        1 tctcgtttgt cgcaaccaaa taggaagaca tcgtcacaat tgccctgact acgtccaaga
       61 tggttgcaat caaaaatctt ttcctgctgg ctgccacagc cgtgtctgtt ctagctgctc
      121 cctcgcccct cgacgctcgt gcggtaagag tcacatcgaa aggccttcga aaggatgact
      181 gacatgaccc cctagacctg gacatgcatc aaccaacagc tgaatcccaa gacaaacaaa
      241 tgggaagaca agcggcttct atacaatcaa gccaaagccg aaagcaactc ccaccacgca
      301 cctctttccg acggcaagac cggtagcagc tacccgcact ggttcactaa cggctacgac
      361 gggaatggca agctcatcaa gggtcgcacg cccatcaaat tcggaaaagc cgactgtgac
      421 cgtcccccga agcacagcca gaacggcatg ggcaaggatg accactacct gctggagttc
      481 ccaacttttc cagatggcca cgactataag tttgactcga agaaacccaa ggaagacccg
      541 ggcccagcga gggtcatcta tacttatccc aacaaggtgt tttgcggcat tgtggcccat
      601 cagcggggga atcagggaga cttgagactg tgttctcatt agttatgtgg gtattatgcc
      661 ttaggagggc gttgctgc
//