LOCUS       RABAATG                 1788 bp    mRNA    linear   MAM 07-MAR-1995
DEFINITION  O.cunniculus alpha,alpha-trehalose glucohydrolase mRNA, complete
            cds.
ACCESSION   M55299 M36523
VERSION     M55299.1
KEYWORDS    alpha,alpha-trehalose glucohydrolase; trehalase.
SOURCE      Oryctolagus cuniculus (rabbit)
  ORGANISM  Oryctolagus cuniculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha;
            Leporidae; Oryctolagus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Ruf,J., Wacker,H., James,P., Maffia,M., Seiler,P., Galand,G., von
            Kieckebusch,A., Semenza,G. and Matei,N.
  TITLE     Rabbit small intestinal trehalase. Purification, cDNA cloning,
            expression, and verification of glycosylphosphatidylinositol
            anchoring
  JOURNAL   J. Biol. Chem. 265 (25), 15034-15039 (1990)
   PUBMED   1697585
COMMENT     Original source text: O.cuniculus (strain New Zealand) intestinal
            mucosa, cDNA to mRNA, clone pRtreh14.
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Oryctolagus cuniculus"
                     /mol_type="mRNA"
                     /strain="New Zealand White"
                     /db_xref="taxon:9986"
                     /clone="pRtreh14"
                     /tissue_type="intestinal mucosa"
     CDS             4..1740
                     /EC_number="3.2.1.28"
                     /codon_start=1
                     /product="alpha,alpha-trehalose glucohydrolase"
                     /protein_id="AAA63460.1"
                     /translation="MPGSTWELHLLLLLGLGLGSEQALPPPCESQIYCHGELLHQVQM
                     ARLYPDDKQFVDMPLSTAPDQVLQSFAELAATYNNTVPREQLEKFVQEHFQAVGQELE
                     SWTPGDWKESPQFLQKISDPKLRAWAEQLHLLWKKLGKKIKPEVLSQPERFSLIYSQH
                     PFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVTAYGHIPNGGRVYY
                     LQRSQPPLLTLMMDRYVAHTGDLAFLRENIETLALELDFWAENRTISVSSGGNSHTLN
                     RYHVPYGGPRPESYSKDTELAHTLPEGSWETLWAELKAGAESGWDFSSRWLVGSPNPD
                     SLGSIRTSKLVPVDLNAFLCQAEELLSGFYSRLGNESQATKYRNLRAQRIAALTALLW
                     DEDKGAWFDYDLENQKKNHEFYPSNLTPLWAGCFSDPAIADKALQYLQDSQILNHRHG
                     IPTSLQNTGQQWDFPNAWAPLQDLVIRGLAKSPSARTQEVAFQLAQNWIRTNFDVYSQ
                     RSAMYEKYDISNAQPGGGGEYEVQEGFGWTNGVALMLLDRYGDRLSSGTQLALLEPHC
                     LAAALLLSFLTR"
     sig_peptide     4..60
     mat_peptide     61..1737
                     /product="alpha,alpha-trehalose glucohydrolase"
                     /EC_number="3.2.1.28"
     regulatory      1771..1776
                     /regulatory_class="polyA_signal_sequence"
BASE COUNT          365 a          563 c          534 g          326 t
ORIGIN      
        1 gccatgcccg ggagcacctg ggagctgcac ctgctgcttc tgctggggct ggggctgggg
       61 tccgagcagg ccctcccccc accctgtgag agccagattt actgccatgg ggagctcctg
      121 caccaggtcc agatggcccg gctctacccg gacgataagc agtttgtgga catgccgctg
      181 tccacggctc cagaccaggt tctgcagagc ttcgccgagc tggccgcgac ctacaacaac
      241 accgtcccca gggagcagct cgagaagttt gtccaggagc acttccaggc ggtggggcag
      301 gagctggaat catggacccc cggggactgg aaagagagcc cccagttcct gcagaagatc
      361 tcggacccca agctgcgagc ctgggcagag cagctgcacc tgctctggaa gaagctggga
      421 aagaagataa agccagaggt gctgagccag cctgagcggt tctctctgat ctactctcaa
      481 catcccttca ttgtgcctgg cgggcgcttt gtggagttct actactggga ctcctactgg
      541 gtcatggagg gcctgctcct gtctgagatg gccgagacgg tgaagggcat gctgcaaaac
      601 ttcctggacc tggtgacggc ctatgggcac atccccaatg gtgggcgagt gtactacttg
      661 cagcgcagcc agcccccgct cctgacgctc atgatggacc gatacgtggc gcacaccggt
      721 gaccttgcct tcctacggga gaacattgag accttggcct tggaactgga cttctgggct
      781 gagaacagga ccatctctgt gagctcgggg ggaaacagcc acaccctgaa ccgctatcac
      841 gtcccttacg gggggcccag gcccgagtcc tacagcaaag acacagagct ggcacacacc
      901 ttgccggaag ggagctggga aaccttgtgg gcggagctca aggccggcgc cgagtccggc
      961 tgggacttct cttcgcgctg gctggttggc agcccaaacc cggactcact cggcagcatc
     1021 cgaacgagca agctggtgcc cgtcgacctg aatgccttcc tgtgccaggc cgaagagctg
     1081 ctcagtggct tctacagcag gctcgggaat gaatcccagg ctacgaagta cagaaatctg
     1141 cgggcacagc gcatagcggc cctgacggcc ctcctgtggg acgaggacaa gggcgcttgg
     1201 ttcgactacg accttgagaa ccagaagaag aaccacgagt tttacccgtc caacctcact
     1261 ccactctggg ccggctgctt ctctgaccct gccatcgcag acaaggctct gcagtacctg
     1321 caggacagcc agatcctgaa ccaccgccat ggaatcccaa cctctctcca gaacacaggc
     1381 cagcagtggg actttcccaa tgcctgggcc ccccttcagg atctggtcat cagaggcctg
     1441 gccaagtcgc cttcagctcg gacacaggaa gtggctttcc agctggctca gaactggatc
     1501 cggaccaact ttgatgtcta ctcccaaaga tcagccatgt atgagaagta tgacatcagc
     1561 aatgcacagc cgggtggcgg aggggagtat gaagtgcagg aggggtttgg ctggaccaac
     1621 ggagtcgccc tgatgctcct ggaccgctat ggtgaccggc tgagctcggg gacccagctg
     1681 gcgctcctgg agccccactg cctggccgct gccctcctgc tcagcttcct aacacggtga
     1741 ccacagggcg gcctccctgc acctctgttc attaaacctc tcaccggc
//