LOCUS       FLBHAEA                 1851 bp    RNA     linear   VRL 02-AUG-1993
DEFINITION  Influenza B/England/222/82 hemagglutinin (HA) RNA, complete cds.
ACCESSION   M18384
VERSION     M18384.1
KEYWORDS    haemagglutinin.
SOURCE      Influenza B virus
  ORGANISM  Influenza B virus
            Viruses; Riboviria; Orthornavirae; Negarnaviricota;
            Polyploviricotina; Insthoviricetes; Articulavirales;
            Orthomyxoviridae; Betainfluenzavirus; Betainfluenzavirus
            influenzae.
REFERENCE   1  (bases 1 to 1851)
  AUTHORS   Rota,P.A., Shaw,M.W. and Kendal,A.P.
  TITLE     Comparison of the immune response to variant influenza type B
            hemagglutinins expressed in vaccinia virus
  JOURNAL   Virology 161 (2), 269-275 (1987)
   PUBMED   3318092
COMMENT     Original source text: Influenza B/England/222/82, grown in eggs or
            human MDCK cells, cDNA to RNA, clone pBHAE.
            Draft entry and computer-readable sequence [1] kindly submitted by
            P.A.Rota 07-MAR-1988.
FEATURES             Location/Qualifiers
     source          1..1851
                     /organism="Influenza B virus"
                     /mol_type="genomic RNA"
                     /db_xref="taxon:11520"
     CDS             34..1785
                     /note="hemagglutinin protein"
                     /codon_start=1
                     /protein_id="AAA43698.1"
                     /translation="MKAIIVLLMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGV
                     IPLTTTPTKSHFANLKGTKTRGKLCPNCLNCTDLDVALARPKCMGTIPSAKASILHEV
                     KPVTSGCFPIMHDRTKIRQLPNLLRGYENIKLSTRNVINAERAPGGPYIIGTSGSCPN
                     VTNGNGFFATMAWAVPKDNKTATNPLTVEVPYICTKGEDQITVWGFHSDNAIQMVKLY
                     GDSKPQKFTSSANGVTTHYVSQIGGFPNQTEDGGLPQSGRIVVDYMVQKPGKTGTIVY
                     QRGVLLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNC
                     PIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGV
                     AVAADLKSTQEAINKITKNLNSLSELEVKNLQRLSGAMDELHNEILELDEKVDDLRAD
                     TISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSAVDIGNGCFETKHKCNQTC
                     LDRIAAGTFNAGEFSLPTFDSLNITAASLNDDGLDNHTILLYYSTAASSLAVTLMIAI
                     FIVYMVSRDNVSCSICL"
     variation       668
                     /note="t in egg derived subpopulation; c in MDCK cells"
BASE COUNT          618 a          386 c          398 g          449 t
ORIGIN      262 bp upstream of BglII site.
        1 agcagaagca gagcattttc taatatccac aaaatgaagg caataattgt actactcatg
       61 gtagtaacat ccaatgcaga tcgaatctgc actgggataa catcttcaaa ctcaccccat
      121 gtggtcaaaa cagctactca aggggaagtc aatgtgactg gtgtgatacc actgacaaca
      181 acaccaacca aatctcattt tgcaaatctc aaaggaacaa agaccagagg gaaactatgc
      241 ccaaactgtc tcaactgcac agatctggac gtggccttgg cgagaccaaa gtgtatgggg
      301 accatacctt cggcaaaagc ttcaatactc catgaagtaa aacctgttac atccgggtgc
      361 tttcctataa tgcacgacag aacaaaaatc agacagctgc ccaatcttct cagaggatat
      421 gaaaatatca agttatcaac ccgtaacgtt atcaacgcag aaagggcacc aggagggccc
      481 tacataattg gaacttcagg atcttgccct aacgttacca atggaaacgg attcttcgca
      541 acaatggctt gggctgtccc aaaagacaac aaaacagcaa cgaatccatt aacagtagaa
      601 gtaccataca tttgtacaaa aggagaagac caaattactg tttgggggtt ccattctgat
      661 aacgcaatcc aaatggtaaa actctatgga gactcaaagc ctcaaaagtt cacctcatct
      721 gccaatggag taaccacaca ttatgtttct cagattggtg gcttcccaaa tcaaacagaa
      781 gacggaggac taccacaaag cggcagaatt gttgttgatt acatggtgca aaaacctgga
      841 aaaacaggaa caattgtcta tcaaagaggt gttttattgc ctcaaaaagt gtggtgcgca
      901 agtggcagga gcaaggtaat aaaagggtcc ttgcctttaa ttggtgaagc agattgcctc
      961 cacgaaaaat acggtggatt aaacaaaagc aagccttact acacaggaga gcatgcaaaa
     1021 gccataggaa attgcccaat atgggtgaaa acacccttga agctggccaa tggaaccaaa
     1081 tatagacctc ctgcaaaact attaaaggaa aggggtttct tcggagctat tgctggtttc
     1141 ttggaaggag gatgggaagg aatgattgca ggttggcacg gatacacatc tcatggagca
     1201 catggagtgg cagtggcagc agaccttaag agtacgcaag aagccataaa caagataaca
     1261 aaaaatctca attctttgag tgagctagaa gtaaagaatc ttcaaagact aagcggtgcc
     1321 atggatgaac tccacaacga aatactcgag ctggatgaga aagtggatga tctcagagct
     1381 gatacaataa gctcgcaaat agagcttgca gtcttgcttt ccaacgaagg aataataaac
     1441 agtgaagatg agcatctctt ggcacttgaa agaaaactaa agaaaatgct gggtccctct
     1501 gctgtagaca tagggaatgg atgctttgaa accaaacaca agtgcaacca aacctgctta
     1561 gacaggatag ctgctggcac ctttaatgca ggagaatttt ctcttcccac ctttgattca
     1621 ctaaatatta ctgctgcatc tttaaatgat gatggattgg ataatcatac tatactgctc
     1681 tactactcaa ctgctgcttc tagtttggct gtaacattga tgatagctat ctttattgtt
     1741 tatatggtct ccagagacaa tgtttcttgc tccatctgtc tatagggagg attgagccct
     1801 gtattttcct ttgttgtggt gcttgtttgc ttgttaccat tacagaaaac g
//