LOCUS       HUMRBPB                 2438 bp    mRNA    linear   HUM 26-MAR-1996
DEFINITION  Human (clone E5.1) RNA-binding protein mRNA, complete cds.
ACCESSION   L37368
VERSION     L37368.1
KEYWORDS    RNA-binding protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Badolato,J., Gardiner,E., Morrison,N. and Eisman,J.
  TITLE     Identification and characterisation of a novel human RNA-binding
            protein
  JOURNAL   Gene 166 (2), 323-327 (1995)
   PUBMED   8543184
COMMENT     On Mar 26, 1996 this sequence version replaced gi:598230.
FEATURES             Location/Qualifiers
     source          1..2438
                     /db_xref="H-InvDB:HIT000193304"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="E5.1"
                     /sex="female"
                     /tissue_type="brain"
                     /clone_lib="Stratagene"
                     /dev_stage="2 years old"
     CDS             550..1467
                     /note="putative"
                     /codon_start=1
                     /product="RNA-binding protein"
                     /protein_id="AAA92859.1"
                     /translation="MDLSGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSK
                     DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSA
                     SSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKP
                     TKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEK
                     ALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRS
                     PRRRSPVRRRSRSPGRRRHRSRSSSNSSR"
     misc_binding    1035..1197
                     /note="RRM consensus binding site; contains RNP-1 and
                     RNP-2 consensus sequences"
                     /bound_moiety="RNA"
     CDS             complement(1161..1697)
                     /note="no distinctive protein motifs; ORF"
                     /codon_start=1
                     /protein_id="AAA92860.1"
                     /translation="MSLSSQKTGGNLDRHTASKPTALLQPGPGWQRGAACCLQILPES
                     RVCFPTGLPLARKVTKLSWVGYKLQGRELQWPVYREELELERLLWRRRPGDRDLRRTG
                     DLRLGERDLLLIRGGDLRHIGGGGNILLGGLNLLGGGLGQGASTAVAVISWPSICPPS
                     MCFSAFSASSGFSNSTYA"
     misc_feature    1173..1197
                     /note="consensus octapeptide found in the SR splicing
                     protein family; RS-octapeptide"
     regulatory      1359..1434
                     /regulatory_class="other"
                     /note="nuclear localization signal"
BASE COUNT          578 a          641 c          640 g          579 t
ORIGIN      
        1 attccggagt ttctttgtgg gatgcggtgg aaggtcggcc gatcccccct tcggagtcat
       61 taattcaaac gtgtacccgc gaacgtttcc cggactcccg tgtgcaatta tcggcgctag
      121 gccgtgggga tacggcccac tatggaccga gcacggtggc cgagctcagt ttgatgggtt
      181 accccagagg ggcggatacg ggaaggttaa gtttgttgga ggagaaacgt ggagtaggct
      241 ttttgtcttg attccgcatg aactgtgcct gaaatgtact tttaaatggg gaaggtgctc
      301 tgaagatttg agccgaaacg ccctctcctc gagatttaac taattgttct ctcctctctc
      361 tggctgttgg acgcgcacct ttccggagga tgggggaggt aaccgaggtc ctgagccggt
      421 acctgaactt gggctgctct ttggcgtaaa ttgcaatcga ttagggatcg tttctcagaa
      481 tcaagttaga agtgagagtt cagataagtg aggccgccat tgctgctttg aacacctcag
      541 aaggggagaa tggatttatc aggagtgaaa aagaagagct tgctaggagt caaagaaaat
      601 aataaaaagt ccagcactag ggctccttca cctaccaaac gcaaagaccg ctcagatgag
      661 aagtccaagg atcgctcaaa agataaaggg gccaccaagg agtcgagtga gaaggatcgc
      721 ggccgggaca aaacccgaaa gaggcgcagc gcttccagtg gtagcagcag taccaggtct
      781 cggtccagct cgacttccag ctcaggctcc agcaccagca ctggctcaag cagtggctcc
      841 agctcttcct cagcatccag ccgctcagga agctccagca cctcccgcag ctccagctct
      901 agcagctctt ctggctctcc aagtccttct cggcgcagac acgacaacag gaggcgctcc
      961 cgctccaaat ccaaaccacc taaaagagat gaaaaggaga ggaaaaggcg gagcccatct
     1021 cctaagccca ccaaagtgca cattgggaga ctcacccgga atgtgacaaa ggatcacatc
     1081 atggagatat tttccaccta tgggaaaatt aaaatgattg acatgcccgt ggaaaggatg
     1141 catccccatc tgtccaaagg ctatgcgtac gtagagtttg agaatccaga tgaagccgag
     1201 aaggcgctga agcacatgga tggaggacaa attgatggcc aggagatcac tgccaccgcc
     1261 gtgctggccc cctggcctag gccacccccc aggagattca gccctcccag gagaatgttg
     1321 ccaccaccgc ctatgtggcg caggtctccc ccacggatga ggagaaggtc ccgctccccg
     1381 aggcgcaggt cccccgtgcg ccggagatca cggtccccgg gccgccgccg ccacaggagc
     1441 cgctccagct ccaactcctc ccgataaaca ggccactgaa gctctcgccc ctgtaactta
     1501 taccccaccc agctcagttt tgtcactttt ctagccaaag gaagaccagt aggaaagcaa
     1561 acccttgact ctggcaggat ttgcaggcag caggcagcac ccctctgcca gccgggcccc
     1621 ggctgcagaa gtgctgttgg tttggatgct gtgtgcctgt caagattccc tccggttttc
     1681 tggctagaaa ggctcatccg tttccggttt ctaagagtca gttcagtggc agagccacca
     1741 gggaaaagtg aggctcttgg gggtggtttg accctcttac ctgggagcac acttttccct
     1801 tccccgatga cctgggatgg tggccaggcc gtgcccttgc tgttgctggg cagtgtcctt
     1861 ttggaaaggg agctgcccca ggctttagtg cagctgccaa ccctgttagg cctggcctct
     1921 cgaggcctct tctaatctca agggtcacac cccctcaaag atcctctcac ccatggtagt
     1981 tgctgctcgt ggttctgtct gtccgtgcac cgatgcacac accgcacccc accactgtac
     2041 tctgaaattg gcgagtgagt ggagagccag ctctgcggag tcatcacgca gccatggtgt
     2101 gcctgccgtt catggtggtc tttcaggtta tcttggcaac atgtacattg cttttatttt
     2161 ttttcttttt tgctttcatt gtacagtcag tactataaaa tttctctttt gagttttata
     2221 cctttgtagc attttagatg acattgtgtt tgtactttgt tgtgtagagt ggaagaattg
     2281 tgttgaataa acccaagatc atctgagatg aatattaatt ttattctcat tttatagatg
     2341 aggaaatggg agttttaaag acattcaata actttggcca aggtcattca gctattaaat
     2401 tttaagacca taaaccaatt ggattcctgg aggaattc
//