LOCUS       RATSSADH                1731 bp    mRNA    linear   ROD 22-MAY-1995
DEFINITION  Rat succinate-semialdehyde dehydrogenase (SSADH) mRNA, 3' end.
ACCESSION   L34821
VERSION     L34821.1
KEYWORDS    succinate semialdehyde dehydrogenase.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1731)
  AUTHORS   Chambliss,K.L., Caudle,D.L., Hinson,D.D., Moomaw,C.R.,
            Slaughter,C.A., Jakobs,C. and Gibson,K.M.
  TITLE     Molecular cloning of the mature NAD(+)-dependent succinic
            semialdehyde dehydrogenase from rat and human. cDNA isolation,
            evolutionary homology, and tissue expression
  JOURNAL   J. Biol. Chem. 270 (1), 461-467 (1995)
   PUBMED   7814412
COMMENT     Original source text: Rattus norvegicus (strain Sprague-Dawley)
            (library: lambda ZAP) adult brain cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..1731
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /tissue_type="brain"
                     /dev_stage="adult"
                     /tissue_lib="lambda ZAP"
     gene            1..1731
                     /gene="SSADH"
     CDS             <1..1467
                     /gene="SSADH"
                     /EC_number="1.2.1.24"
                     /function="Oxidation of succinic semialdehyde"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /product="succinate semialdehyde dehydrogenase"
                     /protein_id="AAA67058.1"
                     /translation="VGGPADLHADLLRGDSFVGGRWLPTPATFPVYDPASGAKLGTVA
                     DCGVPEARAAVRAAYDAFSSWKEISVKERSSLLRKWYDLMIQNKDELAKIITAESGKP
                     LKEAQGEILYSAFFLEWFSEEARRVYGDIIYTSAKDKRGLVLKQPVGVASIITPWNFP
                     SAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPPGVYNVIPCSRTKAK
                     EVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQ
                     AVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQG
                     PLINEKAVEKVEKHVNDAVAKGATVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEET
                     FGPVAPVIKFDKEEEAVAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLI
                     SSVECPFGGVKQSGLGREGSKYGIDEYLEVKYVCYGGL"
     mat_peptide     <1..1464
                     /gene="SSADH"
                     /product="succinate semialdehyde dehydrogenase"
                     /experiment="experimental evidence, no additional details
                     recorded"
     regulatory      1483..1488
                     /regulatory_class="polyA_signal_sequence"
                     /gene="SSADH"
                     /note="putative"
BASE COUNT          420 a          435 c          482 g          394 t
ORIGIN      
        1 gttggtggtc ctgccgacct ccacgccgac ctgctccgcg gggacagctt tgtgggcggc
       61 cgctggcttc caacccctgc caccttccct gtgtatgacc cggccagcgg cgccaagctg
      121 ggcaccgtgg ccgactgcgg ggtaccggag gcccgcgctg ctgtgcgcgc cgcctacgat
      181 gccttcagca gctggaaaga gatctcggtc aaggagagga gctcattgct ccgtaaatgg
      241 tacgacttaa tgatacaaaa caaggacgag cttgccaaga tcataacagc tgagagtgga
      301 aagccactga aagaggccca gggagagatc ctgtattcag cgtttttcct ggagtggttc
      361 tcagaggaag ctcgccgtgt ttatggagac atcatctata cctctgccaa agataagcga
      421 ggactggtcc tcaagcagcc cgttggtgtg gcgtccatca tcacaccgtg gaattttccc
      481 agtgccatga tcacccggaa agtgggggct gccctggcag ctggctgcac tgtggtggta
      541 aaacctgctg aagatacacc ctattctgcc ctggccctgg ctcagcttgc aaaccaggca
      601 ggaatccctc caggtgtcta taatgtcatt ccctgctcta gaaccaaggc caaggaagtg
      661 ggagaggtgc tgtgtactga tcccctcgtg tccaaaatct cctttactgg ctcaacggca
      721 acgggaaaga tcctgctgca tcatgcagca aattctgtga agcgtgtctc catggagctg
      781 ggtggcctcg ccccattcat tgtctttgac agtgccaacg tggaccaggc tgtcgcagga
      841 gcaatggcat ctaaatttag gaatgctggg cagacttgcg tttgctcaaa cagattcttg
      901 gtacaacggg gtatccacga ttcctttgta acgaagtttg cagaagcgat gaagaaaagc
      961 ctgcgtgtag gtaacggatt tgaggaagga acaactcaag ggccattaat taatgagaaa
     1021 gctgtagaaa aggtagagaa gcatgtgaat gacgcagttg ccaaaggggc cacggttgtg
     1081 acaggcggga agcgacacca gagcggaggg aatttcttcg aacccaccct gctcagcaac
     1141 gtcaccaggg acatgctctg catcaccgag gagacctttg ggcccgtggc gccagtcatc
     1201 aagttcgata aagaggaaga ggctgtcgcc atcgcaaatg cagctgatgt tggattggca
     1261 ggttactttt actctcaaga cccagcccag atctggagag tggcggagca gctggaggtg
     1321 ggcatggttg gcgtgaacga aggactgatc tcttcagtgg agtgcccttt tggtggggtg
     1381 aaacagtcgg gccttgggcg agaagggtcc aagtatggca ttgacgaata tctagaggtc
     1441 aaatatgtgt gttatggagg cttgtagggt tctcacttct ttaataaatt acctagatcc
     1501 atagggacat tccatccatt tttttacaat gaacaagtag gttatcagag ttatgaattt
     1561 ttaaaaattc agccggtcct gtcttagatg tacaccctaa cccttccctt atctaactag
     1621 gaaccaatgg acaccatata cctgtggctg tgggtcccag ccagtgctga gaccccagca
     1681 caaccccact gcctccatac aaagtacagt gtgagtgttc acatgccctc t
//