LOCUS       RATGLYP                 1737 bp    mRNA    linear   ROD 29-JUN-1994
DEFINITION  Rattus norvegicus glypican mRNA, complete cds.
ACCESSION   L34067
VERSION     L34067.1
KEYWORDS    glypican.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1737)
  AUTHORS   Litwack,E.D., Stipp,C.S., Kumbasar,A. and Lander,A.D.
  TITLE     Neuronal expression of glypican, a cell-surface
            glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan,
            in the adult rat nervous system
  JOURNAL   J. Neurosci. 14 (6), 3713-3724 (1994)
   PUBMED   8207484
COMMENT     Original source text: Rattus norvegicus (strain New England
            Deconess Hospital) cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..1737
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="New England Deconess Hospital"
                     /db_xref="taxon:10116"
                     /cell_line="PC12"
     CDS             55..1731
                     /note="amino acid feature: GPI-attachment site (C-terminal
                     peptide), aa 531 .. 558; amino acid feature: potential
                     N-linked glycosylation site, aa 79 .. 81 and aa 116 ..
                     118; amino acid feature: potential glycosamino-glycan
                     attachment site, aa 486 .. 491"
                     /codon_start=1
                     /product="glypican"
                     /protein_id="AAA41251.1"
                     /translation="MELRARGWWLLCAAAALVACARGDPASKSRSCSEVRQIYGAKGF
                     SLSDVPQAEISGEHLRICPQGYTCCTSEMEENLANHSRMELETALHDSSRALQATLAT
                     QLHGIDDHFQRLLNDSERTLQDAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLE
                     ETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFV
                     AARSFVQGLGVASDVVRKVAQVPLAPECSRAVMKLVYCAHCRGVPGARPCPDYCRNVL
                     KGCLANQADLDAEWRNLLDSMVLITDKFWGPSGAENVIGSVHMWLAEAINALQDNKDT
                     LTAKVIQGCGNPKVNPHGSGPEEKRRRGKLALQEKSSTGTLEKLVSEAKAQLRDIQDY
                     WISLPGTLCSEKMAMSPASDDRCWNGISKGRYLPEVMGDGLANQINNPEVEVDITKPD
                     MTIRQQIMQLKIMTNRLRGAYGGNDVDFQDASDDGSGSGSGGGCPDDACGRRVSKKSS
                     SSRTPLTHALPGLSEQEGQKTSAATRPEPHYFFLLFLFTLVLAAARPRWR"
     sig_peptide     55..123
     mat_peptide     124..1728
                     /product="glypican"
BASE COUNT          334 a          543 c          553 g          307 t
ORIGIN      
        1 cggccgggat ccagggaggc gcgcacgggc ggccggggag ccgcgggccc cgccatggag
       61 ctccgggccc gaggctggtg gctgctgtgc gcggccgccg cgctagtcgc ctgcgcccgc
      121 ggggaccccg ccagcaagag ccggagctgc agcgaagtcc gccagatcta cggggctaag
      181 ggctttagcc tgagcgacgt gccccaggca gagatctcgg gagagcacct gcggatctgc
      241 ccccagggct acacctgctg caccagtgag atggaggaga acctggccaa ccacagccgg
      301 atggagctgg agaccgcact ccacgacagc agccgtgccc tgcaggctac actggccacc
      361 cagctgcatg gcatcgatga ccacttccag cgcctgctga atgactcgga gcgtacactg
      421 caggatgctt ttcccggggc ctttggggac ctgtacacgc agaacactcg ggccttccgg
      481 gacctgtatg ctgagctgcg tctctactac cgaggggcca acctacacct tgaggagaca
      541 ctggccgagt tctgggcacg gctgctggag cgtctcttca agcagctgca cccccagctt
      601 ctgctgcccg atgactatct ggactgcctg ggcaagcagg cagaggcact gcggccgttt
      661 ggggatgccc ctcgagaact gcgcctgagg gccacccgtg cttttgtggc ggcacgatcc
      721 tttgtgcagg gcctgggtgt ggccagtgac gtagtccgaa aggtggccca ggttcctctg
      781 gccccagaat gttctcgggc tgtcatgaag ttggtctact gtgcccattg ccggggagtc
      841 cctggtgccc ggccctgtcc cgactattgc cgaaatgtgc tcaaaggctg ccttgccaac
      901 caggccgacc tggatgccga gtggaggaac ctcctggact ccatggtgct catcactgac
      961 aagttctggg gcccgtcggg tgcggagaat gtcattggca gtgtgcatat gtggctggcg
     1021 gaggccatca acgccctcca ggacaacaag gacacactca cagctaaggt catccagggc
     1081 tgcggaaacc ccaaggtcaa tccccatggc tctgggcctg aggagaagcg tcgccgtggc
     1141 aaactggcac tgcaggagaa gtcctccaca ggtactctgg aaaagctggt ctctgaggcc
     1201 aaggcccagc tccgagacat tcaggactac tggatcagcc tcccagggac actgtgtagt
     1261 gagaagatgg ccatgagtcc tgccagcgat gaccgctgct ggaatgggat ttccaagggc
     1321 cggtacctac ctgaggtgat gggtgatggg ctggccaacc agatcaacaa ccctgaagtg
     1381 gaggtggaca tcaccaagcc ggatatgacc atccggcagc agatcatgca gctcaagatc
     1441 atgaccaacc gtttacgtgg cgcctacggt ggcaatgatg tggacttcca ggatgccagt
     1501 gatgacggca gtggctccgg cagcggtggc ggatgcccag atgacgcctg tggccggagg
     1561 gtcagcaaga agagctccag ctcccggacc cccttgaccc atgccctccc cggcttgtca
     1621 gaacaggagg gacagaagac ctcggccgcc actcgcccag agcctcacta cttctttctg
     1681 ctcttcctgt tcaccttggt ccttgctgca gccaggccca ggtggcggta actgccc
//