LOCUS       ECOCRA                  1232 bp    DNA     linear   BCT 16-JUN-1994
DEFINITION  Escherichia coli Mg2+ transport protein (corA) gene, complete cds.
ACCESSION   L11042
VERSION     L11042.1
KEYWORDS    Mg2+ transport protein; corA gene.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Hmiel,S.P., Snavely,M.D., Miller,C.G. and Maguire,M.E.
  TITLE     Magnesium transport in Salmonella typhimurium: characterization of
            magnesium influx and cloning of a transport gene
  JOURNAL   J. Bacteriol. 168 (3), 1444-1450 (1986)
   PUBMED   3536881
REFERENCE   2  (bases 1 to 1232)
  AUTHORS   Daniels,D.L., Plunkett,G. III, Burland,V. and Blattner,F.R.
  TITLE     Analysis of the Escherichia coli genome: DNA sequence of the region
            from 84.5 to 86.5 minutes
  JOURNAL   Science 257 (5071), 771-778 (1992)
   PUBMED   1379743
REFERENCE   3  (bases 1 to 1232)
  AUTHORS   Smith,R.L., Banks,J.L., Snavely,M.D. and Maguire,M.E.
  TITLE     Sequence and topology of the CorA magnesium transport systems of
            Salmonella typhimurium and Escherichia coli. Identification of a
            new class of transport protein
  JOURNAL   J. Biol. Chem. 268 (19), 14071-14080 (1993)
   PUBMED   8314774
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:562"
     gene            261..1211
                     /gene="corA"
     CDS             261..1211
                     /gene="corA"
                     /function="Mg2+ influx and efflux"
                     /function="a 39 kDa protein (on protein gels) that by
                     itself mediates Mg2+ influx, but with CorBCD loci, also
                     mediates Mg2+ efflux."
                     /standard_name="CorA"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /citation=[1]
                     /citation=[2]
                     /citation=[3]
                     /codon_start=1
                     /transl_table=11
                     /product="Mg2+ transport protein"
                     /protein_id="AAB59046.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQRPATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAALAPYLYFKRKNWL"
     misc_difference 1160..1161
                     /gene="corA"
                     /note="The Daniels et al. sequence (Acc.#M87049) is
                     missing a second C at this position that changes the
                     reading frame from 344a.a. to 316 a.a."
                     /citation=[2]
                     /replace="c"
BASE COUNT          285 a          314 c          324 g          309 t
ORIGIN      
        1 aaaattttgc tggcgtaaca tgcgcgcacg atcactctaa gaggacattc gccttggaca
       61 cacccagtag atactggctc actatcctgt catccaggat caactcctaa ggctatccct
      121 ttttgctgat agccttagcg ttgtcagcga cctcaatttt tcccgtcgcg ctgagtcagg
      181 ctgtttaatg gtctgaaacc caatttgttt ctgtgtgccc accgaactgt ccgatatttt
      241 aagcattggg agtcccggtc atgctgagcg catttcaact ggaaaataac cgactgaccc
      301 ggctggaagt cgaagagtca caaccccttg taaatgcagt atggattgat cttgtcgaac
      361 cggacgacga cgagcgactg cgcgtacaat ctgaacttgg ccagaggcct gcaacccgcc
      421 cggaactgga agacatcgaa gcatcggcac gtttctttga agacgacgac ggcctgcata
      481 ttcactcctt cttcttcttt gaagatgcgg aagatcacgc cggtaactcc actgtggcat
      541 ttaccatccg tgatggtcgt ctgtttactc tgcgtgagcg tgaactgccc gcttttcgtc
      601 tgtatcgtat gcgtgcccgt agccagtcga tggtagacgg taacgcctac gagttgctgc
      661 tggatctgtt cgaaaccaaa atcgaacagt tggcagatga aattgaaaat atctatagcg
      721 acctggagca gttgagccgg gtgattatgg aagggcatca gggcgatgag tacgacgagg
      781 cgctctccac tctggcggaa ctggaagata tcggctggaa agttcgcctg tgtctgatgg
      841 atacccagcg cgcgctcaac ttcctggtgc gtaaagcgcg tttaccgggt gggcaactgg
      901 agcaggcgcg tgaaatcctg cgagatatcg aatccctgct gccgcataac gaatccctgt
      961 tccagaaggt gaacttcctg atgcaggcgg caatgggttt tatcaacatc gagcagaacc
     1021 gcatcatcaa aatcttctcg gtggtatccg tggtattcct gccgccgacg ctcgttgctt
     1081 ccagctatgg catgaacttt gagtttatgc cagaactgaa gtggagcttc ggctaccctg
     1141 gcgcgattat ctttatgatc ctcgcggccc tggcaccgta tttgtacttt aagcggaaga
     1201 actggttgta aaaaacgaga gcggtggctt ag
//