LOCUS       HQ205476                5358 bp    DNA     linear   HUM 20-JAN-2011
DEFINITION  Homo sapiens isolate MUTYH_C11 A/G-specific adenine DNA glycosylase
            gene, complete cds, alternatively spliced.
ACCESSION   HQ205476
VERSION     HQ205476.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5358)
  AUTHORS   Wang,W., Shen,P., Thiyagarajan,S., Lin,S., Palm,C., Horvath,R.,
            Klopstock,T., Cutler,D., Pique,L., Schrijver,I., Davis,R.W.,
            Mindrinos,M., Speed,T.P. and Scharfe,C.
  TITLE     Identification of rare DNA variants in mitochondrial disorders with
            improved array-based sequencing
  JOURNAL   Nucleic Acids Res. 39 (1), 44-58 (2011)
   PUBMED   20843780
REFERENCE   2  (bases 1 to 5358)
  AUTHORS   Wang,W., Shen,P., Thiyagarajan,S., Lin,S., Palm,C., Horvath,R.,
            Klopstock,T., Cutler,D., Pique,L., Schrijver,I., Davis,R.W.,
            Mindrinos,M., Speed,T.P. and Scharfe,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2010) Biochemistry, Stanford University, 855 S
            California Ave, Palo Alto, CA 94304, USA
FEATURES             Location/Qualifiers
     source          1..5358
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /isolate="MUTYH_C11"
                     /db_xref="taxon:9606"
     mRNA            join(<235..270,1013..1133,1921..2111,2200..2239,
                     2354..2427,2565..2606,2690..2761,2837..2950,3036..3133,
                     3214..3358,3438..3501,3675..3863,3968..4104,4190..4342,
                     4967..5008,5145..>5276)
                     /product="A/G-specific adenine DNA glycosylase"
     mRNA            join(<235..270,1013..1133,1930..2111,2200..2239,
                     2354..2427,2565..2606,2690..2761,2837..2950,3036..3133,
                     3214..3358,3438..3501,3675..3863,3968..4104,4190..4342,
                     4967..5008,5145..>5276)
                     /product="A/G-specific adenine DNA glycosylase"
     mRNA            join(<235..270,1013..1133,1963..2111,2200..2239,
                     2354..2427,2565..2606,2690..2761,2837..2950,3036..3133,
                     3214..3358,3438..3501,3675..3863,3968..4104,4190..4342,
                     4967..5008,5145..>5276)
                     /product="A/G-specific adenine DNA glycosylase"
     CDS             join(235..270,1013..1133,1921..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..5276)
                     /note="alternatively spliced"
                     /codon_start=1
                     /product="A/G-specific adenine DNA glycosylase"
                     /protein_id="ADP90986.1"
                     /translation="MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNS
                     QAKPSACDACAGMIAECPGAPAGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLS
                     WYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQ
                     DLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRY
                     TAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPG
                     DFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAP
                     NTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQR
                     PNSGLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIK
                     LTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGS
                     KRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ"
     CDS             join(235..270,1013..1133,1930..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..5276)
                     /note="alternatively spliced"
                     /codon_start=1
                     /product="A/G-specific adenine DNA glycosylase"
                     /protein_id="ADP90985.1"
                     /translation="MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNS
                     QAKPSACDGMIAECPGAPAGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYD
                     QEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLA
                     SASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAG
                     AIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFN
                     QAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTG
                     QCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNS
                     GLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTY
                     QVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRS
                     QVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ"
     CDS             join(235..270,1013..1133,1963..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..5276)
                     /note="alternatively spliced"
                     /codon_start=1
                     /product="A/G-specific adenine DNA glycosylase"
                     /protein_id="ADP90984.1"
                     /translation="MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNS
                     QAKPSACDGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRR
                     AEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLW
                     AGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQAT
                     GVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVC
                     TPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEP
                     WDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPS
                     VTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQT
                     PVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKP
                     RMGQQVLDNFFRSHISTDAHSLNSAAQ"
     gap             289..355
                     /estimated_length=67
     gap             532..535
                     /estimated_length=4
     variation       594
     gap             609..708
                     /estimated_length=unknown
     gap             895..994
                     /estimated_length=unknown
     mRNA            join(<1019..1133,1960..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..>5276)
                     /product="A/G-specific adenine DNA glycosylase"
     mRNA            join(<1019..1133,1963..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..>5276)
                     /product="A/G-specific adenine DNA glycosylase"
     CDS             join(1019..1133,1960..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..5276)
                     /note="alternatively spliced"
                     /codon_start=1
                     /product="A/G-specific adenine DNA glycosylase"
                     /protein_id="ADP90988.1"
                     /translation="MRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDAGLARQ
                     PEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYA
                     VWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQ
                     EGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCR
                     VRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVE
                     SLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRK
                     ASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKA
                     LLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLT
                     QEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRS
                     HISTDAHSLNSAAQ"
     CDS             join(1019..1133,1963..2111,2200..2239,2354..2427,
                     2565..2606,2690..2761,2837..2950,3036..3133,3214..3358,
                     3438..3501,3675..3863,3968..4104,4190..4342,4967..5008,
                     5145..5276)
                     /note="alternatively spliced"
                     /codon_start=1
                     /product="A/G-specific adenine DNA glycosylase"
                     /protein_id="ADP90987.1"
                     /translation="MRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDGLARQP
                     EEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAV
                     WVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQE
                     GARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRV
                     RAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVES
                     LCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKA
                     SRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKAL
                     LQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQ
                     EEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSH
                     ISTDAHSLNSAAQ"
     gap             1152..1911
                     /estimated_length=760
     gap             2130..2181
                     /estimated_length=52
     gap             2258..2335
                     /estimated_length=78
     gap             2446..2546
                     /estimated_length=101
     gap             2625..2671
                     /estimated_length=47
     gap             2780..2818
                     /estimated_length=39
     gap             2969..3017
                     /estimated_length=49
     gap             3152..3195
                     /estimated_length=44
     gap             3377..3419
                     /estimated_length=43
     gap             3520..3656
                     /estimated_length=137
     variation       3690
     gap             3882..3949
                     /estimated_length=68
     gap             4123..4171
                     /estimated_length=49
     gap             4372..4749
                     /estimated_length=378
     gap             4790..4948
                     /estimated_length=159
     gap             5027..5126
                     /estimated_length=unknown
BASE COUNT          606 a          852 c          894 g          631 t
ORIGIN      
        1 caacgctcca ggcttttgca gccggagccg cggtgtacaa cggaacttgt agtctcctcg
       61 tggctagttc aggcggaagg agcagtcctc tgaagcttga ggagcctcta gaactatgag
      121 cccgaggcct tcccctctcc cagagcgcag aggctttgaa ggctacctct gggaagccgc
      181 tcaccgtcgg aagctgcggg agctgaaact gcgccatcgt cactgtcggc ggccatgaca
      241 ccgctcgtct cccgcctgag tcgtctgtgg gtacgctgga cttgcggtnn nnnnnnnnnn
      301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnncgaac
      361 ttccgttcag acgtcccggg tccggcgcgg ggaaggcagc ctggcgcgcg ctaattgcct
      421 attggcctgt gctgccggct cgcagcccgg gtggacccga gccacgcccc ctggagtgcg
      481 ccggaaagcc gggcgcgcta gagctcgcgg gaggtaatct ttctctcctg cnnnngcggc
      541 gggaacgcgg ggcctccgtg ttctgctgtc ttcatcagcg tgggccgcgg gtagggggta
      601 gtggggtgnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnca ttaattcatt
      721 taacaggtat ctattgtgta cagtttacct ggcactgact ttggacacac accaatcaac
      781 aagagaatca gtccttgcac tcaagtcgtt ttttacagtc aaattcagga agtacacact
      841 gatggaaaga atcaaagtaa tgtaaaatta cattaggtaa gagctacaag gcagnnnnnn
      901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnntgggtc tttttgtttc aggccatcat
     1021 gaggaagcca cgagcagccg tgggaagtgg tcacaggaag caggcagcca gccaggaagg
     1081 gaggcagaag catgctaaga acaacagtca ggccaagcct tctgcctgtg atggtaagga
     1141 actaggttgt gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngatgcacag
     1921 cctgtgcagg gatgattgct gagtgtcctg gggccccagc aggcctggcc aggcagccgg
     1981 aagaggtggt attgcaggcc tctgtctcct cataccatct attcagagac gtagctgaag
     2041 tcacagcctt ccgagggagc ctgctaagct ggtacgacca agagaaacgg gacctaccat
     2101 ggagaagacg ggtaggcagg cgaggagcan nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2161 nnnnnnnnnn nnnnnnnnnn nctggggttg cattgacagg cagaagatga gatggacctg
     2221 gacaggcggg catatgctgg tcagtacatc tcctgagnnn nnnnnnnnnn nnnnnnnnnn
     2281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnccaac
     2341 ccctttcccc cagtgtgggt ctcagaggtc atgctgcagc agacccaggt tgccactgtg
     2401 atcaactact ataccggatg gatgcaggtg actccagggg aggaannnnn nnnnnnnnnn
     2461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2521 nnnnnnnnnn nnnnnnnnnn nnnnnngcct gcctgtggct atagaagtgg cctacactgc
     2581 aggacctggc cagtgcttcc ctggaggtga gagccaccct agggnnnnnn nnnnnnnnnn
     2641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nctctgatcc tacccacagg aggtgaatca
     2701 actctgggct ggcctgggct actattctcg tggccggcgg ctgcaggagg gagctcggaa
     2761 ggtaagggga tggcaggagn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngt
     2821 cttgcactcc aatcaggtgg tagaggagct agggggccac atgccacgta cagcagagac
     2881 cctgcagcag ctcctgcctg gcgtggggcg ctacacagct ggggccattg cctctatcgc
     2941 ctttggccag gtgatctcac agcccaccnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3001 nnnnnnnnnn nnnnnnnttg gcccctctgt gccaggcaac cggtgtggtg gatggcaacg
     3061 tagcacgggt gctgtgccgt gtccgagcca ttggtgctga tcccagcagc acccttgttt
     3121 cccagcagct ctggtaggat gttggggtaa cnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3181 nnnnnnnnnn nnnnnagtgt tcccttcttt taggggtcta gcccagcagc tggtggaccc
     3241 agcccggcca ggagatttca accaagcagc catggagcta ggggccacag tgtgtacccc
     3301 acagcgccca ctgtgcagcc agtgccctgt ggagagcctg tgccgggcac gccagagagt
     3361 aagcctactg gggaagnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc
     3421 aaccctgtgc ctctcaggtg gagcaggaac agctcttagc ctcagggagc ctgtcgggca
     3481 gtcctgacgt ggaggagtgt ggtgagcacc aaacctagcn nnnnnnnnnn nnnnnnnnnn
     3541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnngggg
     3661 atctccgttc ccagctccca acactggaca gtgccacctg tgcctgcctc cctcggagcc
     3721 ctgggaccag accctgggag tggtcaactt ccccagaaag gccagccgca agccccccag
     3781 ggaggagagc tctgccacct gtgttctgga acagcctggg gcccttgggg cccaaattct
     3841 gctggtgcag aggcccaact caggtacctg gatactgggc gnnnnnnnnn nnnnnnnnnn
     3901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng gctgccctcc
     3961 ctctcaggtc tgctggcagg actgtgggag ttcccgtccg tgacctggga gccctcagag
     4021 cagcttcagc gcaaggccct gctgcaggaa ctacagcgtt gggctgggcc cctcccagcc
     4081 acgcacctcc ggcaccttgg ggaggtaagt gagcagcgga atnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nccttgaccc ttcctccagg ttgtccacac
     4201 cttctctcac atcaagctga catatcaagt atatgggctg gccttggaag ggcagacccc
     4261 agtgaccacc gtaccaccag gtgctcgctg gctgacgcag gaggaatttc acaccgcagc
     4321 tgtttccacc gccatgaaaa aggcactacc tttgttgtct ttgttgtact tnnnnnnnnn
     4381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnt ttcaccatgt tggccaggct ggtctcaaac tcctggcctn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnncc ctgtcttctt gtctaggttt tccgtgtgta
     4981 tcagggccaa cagccaggga cctgtatggt aagtctccta ggcctcnnnn nnnnnnnnnn
     5041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5101 nnnnnnnnnn nnnnnnnnnn nnnnnncctt ccattttttc acagggttcc aaaaggtccc
     5161 aggtgtcctc tccgtgcagt cggaaaaagc cccgcatggg ccagcaagtc ctggataatt
     5221 tctttcggtc tcacatctcc actgatgcac acagcctcaa cagtgcagcc cagtgacacc
     5281 tctgaaagcc cccattccct gagaatcctg ttgttagtaa agtgcttatt tttgtagtta
     5341 ttttatgttg tatttttt
//