LOCUS       AY010723                1572 bp    mRNA    linear   ROD 22-JUL-2016
DEFINITION  Mus musculus myosin phosphatase targeting subunit 3 MYPT3 mRNA,
            partial cds.
ACCESSION   AY010723
VERSION     AY010723.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1572)
  AUTHORS   Skinner,J.A. and Saltiel,A.R.
  TITLE     Cloning and identification of MYPT3: a prenylatable myosin
            targetting subunit of protein phosphatase 1
  JOURNAL   Biochem. J. 356 (Pt 1), 257-267 (2001)
   PUBMED   11336659
REFERENCE   2  (bases 1 to 1572)
  AUTHORS   Skinner,J.A. and Saltiel,A.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-OCT-2000) Departments of Physiology and Internal
            Medicine, The University of Michigan School of Medicine, MSRB I,
            Room 4504, 1150 West Medical Center Drive, Ann Arbor, MI
            48109-0650, USA
FEATURES             Location/Qualifiers
     source          1..1572
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /cell_line="3T3-L1"
     CDS             1..>1572
                     /function="inhibits protein phosphatase 1 activity toward
                     phosphorylase, myosin light chain, and myosin substrates"
                     /note="58-kDa; farnesylated by purified recombinant
                     farnesyltransferase in vitro"
                     /codon_start=1
                     /product="myosin phosphatase targeting subunit 3 MYPT3"
                     /protein_id="AAG40949.1"
                     /translation="MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEA
                     HSKKGHGERPWKEVAGLRPRKHVLFPPSVALLEAAARNDLEEVRQFLTSGVSPNLANE
                     DGLTALHQCCIDDFQEMAQQLLDAGADVNARDSECWTPLHAAATCGHLHLVELLISRG
                     ADLLAVNSDGNMPYDLCEDAQTLDCLETAMANQGITQEGIEEARAVPELCMLNDLQNR
                     LQAGANLSDPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAYWG
                     QVHLVELLVAHGADLNGKSLVDETPLDVCGDEEVRAKLLELKHKQDALLRAQGRQRSL
                     LRRRTSSAGSRGKVVRRVSLTHRTNLYRKEHAQEAIVWQQPPPTSPEPLEDEDRQTDA
                     ELRLQPPEDDGPEVARPHNGQVGAPPGRHLYSKRLDRSVSYHLSPEENSAPDALVRDK
                     AHHTLAELKRQRAAAKLQRPAPEGPETFEPGLSVDAGTSQPDCGFSTIGDPPLLKLTA
                     PSEEASVEKRPCCLLM"
BASE COUNT          333 a          458 c          493 g          288 t
ORIGIN      
        1 atggccgagc acctggagct gctggcagag atgcccatgg taggcaggat gagtacccag
       61 gagcgcctga agcatgccca gaagcgacgt gcccagcagg taaagatgtg ggcccaggct
      121 gagaaggagg ctcacagcaa gaagggccat ggggagcgac catggaagga ggtggctggc
      181 ctcaggcctc ggaagcatgt cctcttccct cccagcgttg cccttctgga ggctgctgcc
      241 cgaaacgact tggaggaagt ccgccagttc cttaccagtg gggttagccc caacctggcc
      301 aatgaagatg gcttgactgc actgcaccag tgctgcattg acgacttcca agagatggca
      361 cagcagctcc tggacgctgg ggctgatgtc aatgctcgag acagtgagtg ctggacacct
      421 ctgcatgctg cagctacctg tggccatctg catctggtgg aactccttat ttcacgtggt
      481 gcagatctcc ttgcagtcaa ttccgatggg aatatgccct acgacctgtg tgaggacgca
      541 cagacgctgg attgccttga gactgccatg gccaaccagg gtatcaccca ggagggcatt
      601 gaggaggccc gggcagtgcc agagctgtgc atgctgaatg acctccagaa ccgcctgcaa
      661 gctggggcca acctcagtga ccctttggat catggggcta ctctgctgca catcgccgct
      721 gctaatgggt tcagtgaggt ggctaccctg ctgctggagc aaggcgccag cctgagcgct
      781 aaggaccatg atggctggga gcctctgcat gctgcggctt actggggcca ggtacacctg
      841 gtagaattgc ttgtggcaca tggggctgat ctgaatggaa aatctctggt ggacgagaca
      901 cccctcgatg tatgtggtga tgaggaggtg agagccaaac tgctggagct caagcacaag
      961 caagatgcac tcctgcgggc ccagggccgc cagcgctccc tgctgcgccg ccgtacctct
     1021 agtgcaggca gccgtgggaa ggtggtgaga cgagtgagcc tgacacatcg caccaacctg
     1081 taccgcaagg agcatgccca agaggccatt gtgtggcagc agccgccacc caccagtcca
     1141 gaacctctag aggatgagga caggcagaca gacgctgagc tccggctgca gcccccggag
     1201 gacgatggtc ctgaggtggc cagaccacac aatggccaag taggggcccc ccccgggaga
     1261 cacctgtact ccaagcgtct agatcggagt gtctcctatc atctgagtcc tgaggagaac
     1321 agtgcccctg atgccctcgt ccgggacaag gcccaccaca cactggcaga actgaaacgc
     1381 cagcgagcgg ctgcaaagct tcagcgacct gcccctgaag ggcctgagac ttttgagcct
     1441 ggcctgtctg ttgatgctgg gacctcccag cctgactgtg gcttcagcac aattggggac
     1501 ccgcccctgc tcaagctcac tgctccctcg gaggaggcgt ctgtggagaa gaggccgtgt
     1561 tgcttgctca tg
//