LOCUS       AK315651                1710 bp    mRNA    linear   HTC 24-MAY-2008
DEFINITION  Homo sapiens cDNA, FLJ96742, Homo sapiens putative intramembrane
            cleaving protease (SPPL2A),mRNA.
ACCESSION   AK315651
VERSION     AK315651.1
KEYWORDS    HTC; HTC_FLI; oligo capping.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1710)
  AUTHORS   Isogai,T. and Yamamoto,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JAN-2008) to the DDBJ/EMBL/GenBank databases.
            Contact:Takao Isogai
            Reverse Proteomics Research Institute; 1-9-11 Kaji-cho,
            Chiyoda-ku, Tokyo 101-0044, Japan
            E-mail :flj-cdna@nifty.com
REFERENCE   2  
  AUTHORS   Wakamatsu,A., Yamamoto,J., Kimura,K., Kaida,T., Tsuchiya,K.,
            Iida,Y., Takayama,Y., Murakawa,K., Kanehori,K., Andoh,T.,
            Kagawa,N., Sato,R., Kawamura,Y., Tanaka,S., Kisu,Y., Sugano,S.,
            Goshima,N., Nomura,N. and Isogai,T.
  TITLE     NEDO functional analysis of protein and research application
            project
  JOURNAL   Unpublished (2008)
COMMENT     Human cDNA sequencing project focused on splicing variants of mRNA
            in NEDO functional analysis of protein and research application
            project supported by Ministry of Economy, Trade and Industry,
            Japan; cDNA selection for complete cds sequencing: Reverse
            Proteomics Research Institute (REPRORI), Hitachi, Ltd., Japan
            (Hitachi) and Japan Biological Informatics Consortium, Japan
            (JBIC); cDNA complete cds sequencing: JBIC and Biological
            Information Research Center (BIRC), AIST; cDNA library
            construction: Helix Research Institute supported by Japan Key
            Technology Center, Japan (HRI); cDNA 5'- & 3'-end sequencing:
            Research Association for Biotechnology, Japan, Biotechnology
            Center, National Institute of Technology and Evaluation, Japan and
            HRI; cDNA mapping to human genome: Central Research Laboratory,
            Hitachi; evaluation and annotation: REPRORI.
FEATURES             Location/Qualifiers
     source          1..1710
                     /clone="SYNOV3000442"
                     /db_xref="H-InvDB:HIT000434517"
                     /db_xref="taxon:9606"
                     /mol_type="mRNA"
                     /note="clone_lib: SYNOV3"
                     /note="cloning vector: pME18SFL3"
                     /organism="Homo sapiens"
                     /tissue_type="synovial membrane tissue from rheumatoid
                     arthritis"
     CDS             148..1710
                     /note="Homo sapiens putative intramembrane cleaving
                     protease (SPPL2A),mRNA"
                     /protein_id="BAG38017.1"
                     /translation="MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCML
                     YNPYWTALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKAR
                     IAQKGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKM
                     YSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTF
                     SPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQC
                     TIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKL
                     PNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKL
                     IYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMIL
                     TFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDCATNEE
                     NPVISGEQIVQQ"
BASE COUNT          446 a          359 c          396 g          509 t
ORIGIN      
        1 agcagcggcg gtccagtcgt agcccggccg cccgcgcctg tccggtccgg tccggccacg
       61 gaggcagcgc agcggcggga ctccgagcct accccgccga gtgagctgcg ccgcaccgtg
      121 ccgtcccacc cggcacccac cagtccgatg gggccgcagc ggcggctgtc ccctgccggg
      181 gccgccctac tctggggctt cctgctccag ctgacagccg ctcaggaagc aatcttgcat
      241 gcgtctggaa atggcacaac caaggactac tgcatgcttt ataaccctta ttggacagct
      301 cttccaagta ccctagaaaa tgcaacttcc attagtttga tgaatctgac ttccacacca
      361 ctatgcaacc tttctgatat tcctcctgtt ggcataaaga gcaaagcagt tgtggttcca
      421 tggggaagct gccattttct tgaaaaagcc agaattgcac agaaaggagg tgctgaagca
      481 atgttagttg tcaataacag tgtcctattt cctccctcag gtaacagatc tgaatttcct
      541 gatgtgaaaa tactgattgc atttataagc tacaaagact ttagagatat gaaccagact
      601 ctaggagata acattactgt gaaaatgtat tctccatcgt ggcctaactt tgattatact
      661 atggtggtta tttttgtaat tgcggtgttc actgtggcat taggtggata ctggagtgga
      721 ctagttgaat tggaaaactt gaaagcagtg acaactgaag atagagaaat gaggaaaaag
      781 aaggaagaat atttaacttt tagtcctctt acagttgtaa tatttgtggt catctgctgt
      841 gttatgatgg tcttacttta tttcttctac aaatggttgg tttatgttat gatagcaatt
      901 ttctgcatag catcagcaat gagtctgtac aactgtcttg ctgcactaat tcataagata
      961 ccatatggac aatgcacgat tgcatgtcgt ggcaaaaaca tggaagtgag acttattttt
     1021 ctctctggac tgtgcatagc agtagctgtt gtttgggctg tgtttcgaaa tgaagacagg
     1081 tgggcttgga ttttacagga tatcttgggg attgctttct gtctgaattt aattaaaaca
     1141 ctgaagttgc ccaacttcaa gtcatgtgtg atacttctag gccttctcct cctctatgat
     1201 gtattttttg ttttcataac accattcatc acaaagaatg gtgagagtat catggttgaa
     1261 ctcgcagctg gaccttttgg aaataatgaa aagttgccag tagtcatcag agtaccaaaa
     1321 ctgatctatt tctcagtaat gagtgtgtgc ctcatgcctg tttcaatatt gggttttgga
     1381 gacattattg taccaggcct gttgattgca tactgtagaa gatttgatgt tcagactggt
     1441 tcttcttaca tatactatgt ttcgtctaca gttgcctatg ctattggcat gatacttaca
     1501 tttgttgttc tggtgctgat gaaaaagggg caacctgctc tcctctattt agtaccttgc
     1561 acacttatta ctgcctcagt tgttgcctgg agacgtaagg aaatgaaaaa gttctggaaa
     1621 ggtaacagct atcagatgat ggaccatttg gattgtgcaa caaatgaaga aaaccctgtg
     1681 atatctggtg aacagattgt ccagcaataa
//