LOCUS       AJ420896                1551 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for SPPL2a protein.
ACCESSION   AJ420896
VERSION     AJ420896.1
KEYWORDS    SPPL2A gene; SPPL2a protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1551)
  AUTHORS   Martoglio B.
  JOURNAL   Submitted (22-NOV-2001) to the INSDC. Martoglio B., Swiss Federal
            Institute of Technology, Institute of Biochemistry, 8093, Zuerich,
            SWITZERLAND.
REFERENCE   2
  AUTHORS   Weihofen A., Binns K., Lemberg M.K., Ashman K., Martoglio B.
  TITLE     Identification of signal peptide peptidase, a presenilin-type
            aspartic protease
  JOURNAL   Science, e1252229 296(5576), 2215-2218(2002).
   PUBMED   12077416
FEATURES             Location/Qualifiers
     source          1..1551
                     /db_xref="H-InvDB:HIT000247896"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     CDS             65..1294
                     /gene="SPPL2A"
                     /product="SPPL2a protein"
                     /function="putative intramembrane cleaving protease"
                     /db_xref="GOA:Q8TCT8"
                     /db_xref="H-InvDB:HIT000247896.12"
                     /db_xref="HGNC:HGNC:30227"
                     /db_xref="InterPro:IPR003137"
                     /db_xref="InterPro:IPR006639"
                     /db_xref="InterPro:IPR007369"
                     /db_xref="InterPro:IPR033151"
                     /db_xref="UniProtKB/Swiss-Prot:Q8TCT8"
                     /protein_id="CAD13133.1"
                     /translation="MLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDN
                     ITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKE
                     EYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI
                     PYGQCTIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLI
                     KTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVI
                     RVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYA
                     IGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDC
                     ATNEENPVISGEQIVQQ"
BASE COUNT          449 a          251 c          323 g          528 t
ORIGIN      
        1 tccatgggga agctgccatt ttcttgaaaa agccagaatt gcacagaaag gaggtgctga
       61 agcaatgtta gttgtcaata acagtgtcct atttcctccc tcaggtaaca gatctgaatt
      121 tcctgatgtg aaaatactga ttgcatttat aagctacaaa gactttagag atatgaacca
      181 gactctagga gataacatta ctgtgaaaat gtattctcca tcgtggccta actttgatta
      241 tactatggtg gttatttttg taattgcggt gttcactgtg gcattaggtg gatactggag
      301 tggactagtt gaattggaaa acttgaaagc agtgacaact gaagatagag aaatgaggaa
      361 aaagaaggaa gaatatttaa cttttagtcc tcttacagtt gtaatatttg tggtcatctg
      421 ctgtgttatg atggtcttac tttatttctt ctacaaatgg ttggtttatg ttatgatagc
      481 aattttctgc atagcatcag caatgagtct gtacaactgt cttgctgcac taattcataa
      541 gataccatat ggacaatgca cgattgcatg tcgtggcaaa aacatggaag tgagacttat
      601 ttttctctct ggactgtgca tagcagtagc tgttgtttgg gctgtgtttc gaaatgaaga
      661 caggtgggct tggattttac aggatatctt ggggattgct ttctgtctga atttaattaa
      721 aacactgaag ttgcccaact tcaagtcatg tgtgatactt ctaggccttc tcctcctcta
      781 tgatgtattt tttgttttca taacaccatt catcacaaag aatggtgaga gtatcatggt
      841 tgaactcgca gctggacctt ttggaaataa tgaaaagttg ccagtagtca tcagagtacc
      901 aaaactgatc tatttctcag taatgagtgt gtgcctcatg cctgtttcaa tattgggttt
      961 tggagacatt attgtaccag gcctgttgat tgcatactgt agaagatttg atgttcagac
     1021 tggttcttct tacatatact atgtttcgtc tacagttgcc tatgctattg gcatgatact
     1081 tacatttgtt gttctggtgc tgatgaaaaa ggggcaacct gctctcctct atttagtacc
     1141 ttgcacactt attactgcct cagttgttgc ctggagacgt aaggaaatga aaaagttctg
     1201 gaaaggtaac agctatcaga tgatggacca tttggattgt gcaacaaatg aagaaaaccc
     1261 tgtgatatct ggtgaacaga ttgtccagca ataatattat gtggaactgc tataatgtgt
     1321 cattgatttt ctacaaatag acttcgactt tttaaattga cttttgaatt gacaatctga
     1381 aagagtcttc aatgatatgc ttgcaaaaat atatttttat gagctggtac tgacagttac
     1441 atcataaata actaaaacgc tttgctttta atgttaaagt tgtgccttca cattaaataa
     1501 aacatatggt ctgtgtagtt tccgagatgt actatataca gtatattttt c
//