LOCUS       AJ345028                1969 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for presenilin-like protein 2 (PSL2 gene).
ACCESSION   AJ345028
VERSION     AJ345028.1
KEYWORDS    Presenilin-like Protein 2; PSL2 gene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1969)
  AUTHORS   Hofmann K.
  JOURNAL   Submitted (12-SEP-2001) to the INSDC. Hofmann K., Bioinformatics
            Group, MEMOREC Stoffel GmbH, Stoeckheimer Weg 1, D-50829 Koeln,
            GERMANY.
REFERENCE   2
  AUTHORS   Irmler M., Tomiuk S., Korner M.R., Hofmann K., Conradt M.
  TITLE     Characterization of a new protein family with homology to
            presenilins
  JOURNAL   Unpublished.
FEATURES             Location/Qualifiers
     source          1..1969
                     /db_xref="H-InvDB:HIT000247232"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     CDS             159..1721
                     /gene="PSL2"
                     /product="presenilin-like protein 2"
                     /function="putative intramembrane protease"
                     /db_xref="GOA:Q8TCT8"
                     /db_xref="H-InvDB:HIT000247232.14"
                     /db_xref="HGNC:HGNC:30227"
                     /db_xref="InterPro:IPR003137"
                     /db_xref="InterPro:IPR006639"
                     /db_xref="InterPro:IPR007369"
                     /db_xref="InterPro:IPR033151"
                     /db_xref="UniProtKB/Swiss-Prot:Q8TCT8"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /protein_id="CAC87789.1"
                     /translation="MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCML
                     YNPYWTALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKAR
                     IAQKGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKM
                     YSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTF
                     SPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQC
                     TIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKL
                     PNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKL
                     IYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMIL
                     TFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDCATNEE
                     NPVISGEQIVQQ"
BASE COUNT          531 a          396 c          438 g          604 t
ORIGIN      
        1 gcggccgctg tagcagcggc tgtccagtcg tagcccggcc gcccgcgcct gtccggtccg
       61 gtccggccac ggaggcagcg cagcggcggg actccgagcc taccccgccg agtgagctgc
      121 gccgcaccgt gccgtcccac ccggcaccca ccagtccgat ggggccgcag cggcggctgt
      181 cccctgccgg ggccgcccta ctctggggct tcctgctcca gctgacagcc gctcaggaag
      241 caatcttgca tgcgtctgga aatggcacaa ccaaggacta ctgcatgctt tataaccctt
      301 attggacagc tcttccaagt accctagaaa atgcaacttc cattagtttg atgaatctga
      361 cttccacacc actatgcaac ctttctgata ttcctcctgt tggcataaag agcaaagcag
      421 ttgtggttcc atggggaagc tgccattttc ttgaaaaagc cagaattgca cagaaaggag
      481 gtgctgaagc aatgttagtt gtcaataaca gtgtcctatt tcctccctca ggtaacagat
      541 ctgaatttcc tgatgtgaaa atactgattg catttataag ctacaaagac tttagagata
      601 tgaaccagac tctaggagat aacattactg tgaaaatgta ttctccatcg tggcctaact
      661 ttgattatac tatggtggtt atttttgtaa ttgcggtgtt cactgtggca ttaggtggat
      721 actggagtgg actagttgaa ttggaaaact tgaaagcagt gacaactgaa gatagagaaa
      781 tgaggaaaaa gaaggaagaa tatttaactt ttagtcctct tacagttgta atatttgtgg
      841 tcatctgctg tgttatgatg gtcttacttt atttcttcta caaatggttg gtttatgtta
      901 tgatagcaat tttctgcata gcatcagcaa tgagtctgta caactgtctt gctgcactaa
      961 ttcataagat accatatgga caatgcacga ttgcatgtcg tggcaaaaac atggaagtga
     1021 gacttatttt tctctctgga ctgtgcatag cagtagctgt tgtttgggct gtgtttcgaa
     1081 atgaagacag gtgggcttgg attttacagg atatcttggg gattgctttc tgtctgaatt
     1141 taattaaaac actgaagttg cccaacttca agtcatgtgt gatacttcta ggccttctcc
     1201 tcctctatga tgtatttttt gttttcataa caccattcat cacaaagaat ggtgagagta
     1261 tcatggttga actcgcagct ggaccttttg gaaataatga aaagttgcca gtagtcatca
     1321 gagtaccaaa actgatctat ttctcagtaa tgagtgtgtg cctcatgcct gtttcaatat
     1381 tgggttttgg agacattatt gtaccaggcc tgttgattgc atactgtaga agatttgatg
     1441 ttcagactgg ttcttcttac atatactatg tttcgtctac agttgcctat gctattggca
     1501 tgatacttac atttgttgtt ctggtgctga tgaaaaaggg gcaacctgct ctcctctatt
     1561 tagtaccttg cacacttatt actgcctcag ttgttgcctg gagacgtaag gaaatgaaaa
     1621 agttctggaa aggtaacagc tatcagatga tggaccattt ggattgtgca acaaatgaag
     1681 aaaaccctgt gatatctggt gaacagattg tccagcaata atattatgtg gaactgctat
     1741 aatgtgtcat tgattttcta caaatagact tcgacttttt aaattgactt ttgaattgac
     1801 aatctgaaag agtcttcaat gatatgcttg caaaaatata tttttatgag ctggtactga
     1861 cagttacatc ataaataact aaaacgcttt gcttttaatg ttaaagttgt gccttcacat
     1921 taaataaaac atatggtctg tgtagtttcc gagatgtact ataaaaaaa
//