LOCUS       AJ306425                2480 bp    mRNA    linear   ROD 14-NOV-2006
DEFINITION  Mus musculus partial mRNA for hemochromatosis protein (Hfe gene),
            3' UTR long form.
ACCESSION   AJ306425
VERSION     AJ306425.1
KEYWORDS    hereditary hemochromatosis; HFE gene.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2480)
  AUTHORS   Oliva R.
  JOURNAL   Submitted (21-FEB-2001) to the INSDC. Oliva R., Human Genome
            Research Group, Faculty of Medicine and Clinic Hospital, Casanova,
            143, Barcelona, 08036, SPAIN.
REFERENCE   2
  AUTHORS   Sanchez M., Oliva R.
  TITLE     Full characterization of Hereditary Hemochromatosis gene HFE in
            human and mouse
  JOURNAL   Unpublished.
COMMENT     related entry AJ298838
FEATURES             Location/Qualifiers
     source          1..2480
                     /organism="Mus musculus"
                     /chromosome="13"
                     /map="13A2-A4"
                     /mol_type="mRNA"
                     /tissue_type="liver"
                     /db_xref="taxon:10090"
     CDS             <1..106
                     /codon_start=2
                     /gene="HFE"
                     /product="HFE protein"
                     /function="mutated in hereditary hemochromatosis"
                     /db_xref="MGI:MGI:109191"
                     /db_xref="UniProtKB/TrEMBL:Q8R557"
                     /protein_id="CAC81981.1"
                     /translation="TICAIFLVGILFLILRKRKASGGTMGGYVLTDCE"
     3'UTR           107..2480
                     /gene="HFE"
                     /note="long form"
     variation       486
                     /replace="c"
     regulatory      623..628
                     /gene="HFE"
                     /regulatory_class="polyA_signal_sequence"
     variation       818
                     /replace="a"
     repeat_region   1249..1644
                     /rpt_family="LTR/MaLR"
     repeat_region   2017..2104
                     /note="dinucleotide repeat (TG)n"
     regulatory      2444..2449
                     /gene="HFE"
                     /regulatory_class="polyA_signal_sequence"
BASE COUNT          672 a          557 c          521 g          730 t
ORIGIN      
        1 caccatctgt gccatcttct tagttggaat tctgttccta atcttaagga aaaggaaggc
       61 ttcaggagga accatgggtg gctatgtctt aacagactgt gagtgatctg cagcctgctg
      121 aaccacggaa gagagaaaac tcagccaaag acttggaggg ggcacacttg ctccactgta
      181 ggacacagtt ggacctaaca cacagaaact gcctgagaac tgtgctctta gccttctctg
      241 ttcactttct taaggtgttt tctccagtta agttcagttc ctgaatagta gtgattgccc
      301 cagttgcaac ctctccctcc agaactggtc tcatgattct taggctgctt cttggaagca
      361 tcctatgttt ccttcatgca cctagactcc atatgtctac gtaaagagcc cctctaagtt
      421 tagtggatac atgattcgtt tccacatctg aagaagttgt gaaccttcat ccggggatgc
      481 tcacacatac ttgagccaga atttttcacc tatatcctag aatccaggac ccactcaact
      541 atcctccatc tgttatagag tgactcctct gtcaccatgc cctgacttct ctgccattgg
      601 agtgttatat atatggatca tcaataaagc catgaaggct acacaactgt gcaacttgag
      661 gaatcaccct cggagaaaat gtagatgttt gtgtgtataa caatggctct gtgttcatat
      721 ctgcacaaag gtgatttgag gttttcaaag gttaatatca tagacatctg tgacatgatg
      781 cctatgatgt accctctctc cttgtctcga aaatgaagac ggtgaacgat tatcataatg
      841 aagtgtggct tgcacttgtt ctgaggaagt gctcaataat atactctgct ctgatcaccc
      901 gctaaacata aagcatgtgt agacatcctg aggggtctag gaagtggaaa ttattatctg
      961 cacccatgtt ccttctctgt agatgcaaaa ggtgaaaact ctctaaccac tcaccagaga
     1021 tacagaaaga cagctgtaga aatgccatcc tggctcttag atacaccctc tgcaccacca
     1081 gactatatga gtggcatgaa atgagtggag aaagaagatg gcccttttct tgtctcctgg
     1141 ggtttctctt cagtgagttt gacccacaag atgagaaata gctgccaaat actcaccagt
     1201 cctcagctat caggaatcct ttccaagtta gagggaaagg tcagggtgtg tcttagtcag
     1261 ggtttctatt cctgcacaaa catcatgacc aagaagcaag ttggggagga aggggtttat
     1321 tcgggcttac acttccatac tgttgttcat taccaaagga agtcaggact ggaactcaag
     1381 caggtcagaa agcaggagct gatgcagaag ccatggaggg atgttctttg ctggtttgct
     1441 tctcctggct tgctcagcct gctctcttat agaacccaag actaccagcc cagagatggt
     1501 tccacccaca aggggccctc ccccttgatc actaattgag gaaatgcctt acagttggat
     1561 ctcatggagg catttcctca actgaagttc ctttctctgt aataactcca gctgtgtcaa
     1621 gttgacacaa aactagccag tacagggtgc aagtagtgac tccactgccc accagtctcc
     1681 cgcttcctct gacatatggc ttgttgttgt tgttgttgtt tgtttgtttg tttttgttaa
     1741 atttcattaa aaagcttagc ctatctgtct ggtaccctca aagctgatgc ctctggatca
     1801 gaaccttaaa gtgattgccc tggcagccga gaatctgtca atctgtcaat cttaaggcag
     1861 taggatggaa gctgtcattt ggcttggaga attcttggag ttgctggggt cctgctgctc
     1921 attgttaatt gtgcacattt taaaatccaa tctagacaac ctagacatta ctagatttca
     1981 caaaatacat tcatctaatg ttaaaaaggt caagcctgtg cttgcatgtt tgtgtgtgta
     2041 tatacatctg tctgcatgag gatgagtgtt cacatatgtg tgcacgtgta tgcacatgtg
     2101 tgtgggctcc tctctccacc tggatggcac atgctcactt cctcctaaac acacatttgc
     2161 ctgcgtctcc gtggtatgaa ttccatcttg aaacccacat gcctcagacc aatggctcca
     2221 gtttctttaa tgaacactga atttgagctg agacctcaac ctttttgtga cctttgtatt
     2281 atttactgtt tgtgaaaatt aggtaggaaa aaaaaaacat caaaattttg attcattttt
     2341 ggaaatagat aaacgtagtt ccatcatttc ctcaatgaat gacaagaacc actagcagct
     2401 tgtatgttgt ctctgtatga ctctcctcaa agtgtgtgca actaataaac acatgatttg
     2461 gtaagcaaaa aaaaaaaaaa
//