LOCUS       AJ278975                 732 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Homo sapiens mRNA for p53-binding protein (MDM2 gene),
            alternatively spliced variant KB2.
ACCESSION   AJ278975
VERSION     AJ278975.1
KEYWORDS    alternative splicing; mdm2 gene; p53-binding protein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Bartel F.
  JOURNAL   Submitted (06-SEP-2000) to the INSDC. Bartel F., Institute for
            Pathology, University of Halle, Faculty of Medicine, Magdeburger
            St. 14, 06097 Halle, GERMANY.
REFERENCE   3
  AUTHORS   Bartel F., Meye A., Wuerl P., Kappler M., Bache M.,
            Lautenschlager C., Grunbaum U., Schmidt H., Taubert H.
  TITLE     Amplification of the MDM2 gene, but not expression of splice
            variants of MDM2 MRNA, is associated with prognosis in soft tissue
            sarcoma
  JOURNAL   Int. J. Cancer 95(3), 168-175(2001).
   PUBMED   11307150
COMMENT     Related sequences: AJ278975-AJ278978, AJ276888
FEATURES             Location/Qualifiers
     source          1..732
                     /db_xref="H-InvDB:HIT000246481"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /tissue_type="malignant fibrous histiocytoma"
                     /db_xref="taxon:9606"
     mRNA            <1..>732
                     /gene="MDM2"
                     /function="p53-binding protein"
                     /note="alternatively spliced isoform KB2"
     CDS             1..732
                     /gene="MDM2"
                     /standard_name="human homolog of mouse double minute 2"
                     /product="p53-binding protein"
                     /note="alternatively spliced isoform KB2"
                     /db_xref="GOA:Q9H4C5"
                     /db_xref="H-InvDB:HIT000246481.13"
                     /db_xref="HGNC:HGNC:6973"
                     /db_xref="InterPro:IPR001841"
                     /db_xref="InterPro:IPR001876"
                     /db_xref="InterPro:IPR013083"
                     /db_xref="InterPro:IPR015459"
                     /db_xref="InterPro:IPR016495"
                     /db_xref="InterPro:IPR036443"
                     /db_xref="InterPro:IPR036885"
                     /db_xref="UniProtKB/TrEMBL:Q9H4C5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /protein_id="CAC07809.1"
                     /translation="MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQ
                     KDTYTMKEDYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENS
                     TQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQ
                     EDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK
                     KLKKRNKPCPVCRQPIQMIVLTYFP"
BASE COUNT          254 a          141 c          154 g          183 t
ORIGIN      
        1 atgtgcaata ccaacatgtc tgtacctact gatggtgctg taaccacctc acagattcca
       61 gcttcggaac aagagaccct ggttagacca aagccattgc ttttgaagtt attaaagtct
      121 gttggtgcac aaaaagacac ttatactatg aaagaggact attggaaatg cacttcatgc
      181 aatgaaatga atccccccct tccatcacat tgcaacagat gttgggccct tcgtgagaat
      241 tggcttcctg aagataaagg gaaagataaa ggggaaatct ctgagaaagc caaactggaa
      301 aactcaacac aagctgaaga gggctttgat gttcctgatt gtaaaaaaac tatagtgaat
      361 gattccagag agtcatgtgt tgaggaaaat gatgataaaa ttacacaagc ttcacaatca
      421 caagaaagtg aagactattc tcagccatca acttctagta gcattattta tagcagccaa
      481 gaagatgtga aagagtttga aagggaagaa acccaagaca aagaagagag tgtggaatct
      541 agtttgcccc ttaatgccat tgaaccttgt gtgatttgtc aaggtcgacc taaaaatggt
      601 tgcattgtcc atggcaaaac aggacatctt atggcctgct ttacatgtgc aaagaagcta
      661 aagaaaagga ataagccctg cccagtatgt agacaaccaa ttcaaatgat tgtgctaact
      721 tatttcccct ag
//