LOCUS       AJ242798                1563 bp    DNA     linear   MAM 28-NOV-2007
DEFINITION  Bos taurus HBA2 gene for hemoglobin alpha chain, HBA2S allele,
            promoter region and exons 1-3.
ACCESSION   AJ242798
VERSION     AJ242798.2
KEYWORDS    HBA2 gene; hemoglobin alpha chain.
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1
  AUTHORS   Di Luccia A.
  JOURNAL   Submitted (27-MAY-1999) to the INSDC. Di Luccia A., Biochemistry,
            C.N.R. - I.A.B.B.A.M., 80147, Naples, ITALY.
  REMARK    revised by [3]
REFERENCE   2
  AUTHORS   Rullo R., Pieragostini E., Vincenti D., Campanile C., Di Luccia A.
  TITLE     Nucleotide sequence of Podolian cattle (Bos taurus primigenius)
            alpha globin genes
  JOURNAL   Unpublished.
REFERENCE   3  (bases 1 to 1563)
  AUTHORS   Rullo R.
  JOURNAL   Submitted (12-SEP-2007) to the INSDC. Rullo R., Biochemistry,
            C.N.R. - I.A.B.B.A.M., 80147, Naples, ITALY.
COMMENT     Related sequences: AJ242797 (allele HBA1N), AJ242799 (allele
            HBA1Y).
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Bos taurus"
                     /mol_type="genomic DNA"
                     /geo_loc_name="Italy:Puglia"
                     /lat_lon="40.51 N 16.21 E"
                     /sex="female"
                     /haplotype="S (IalphaN-IIalphaS)"
                     /cell_type="leukocytes"
                     /tissue_type="blood"
                     /note="breed: Podolian"
                     /db_xref="taxon:9913"
     regulatory      448..452
                     /gene="HBA2"
                     /allele="HBA2S"
                     /regulatory_class="CAAT_signal"
     regulatory      492..497
                     /gene="HBA2"
                     /allele="HBA2S"
                     /regulatory_class="TATA_box"
     CDS             join(559..653,755..959,1064..1192)
                     /gene="HBA2"
                     /allele="HBA2S"
                     /product="hemoglobin alpha chain"
                     /db_xref="GOA:P01966"
                     /db_xref="InterPro:IPR000971"
                     /db_xref="InterPro:IPR002338"
                     /db_xref="InterPro:IPR002339"
                     /db_xref="InterPro:IPR009050"
                     /db_xref="InterPro:IPR012292"
                     /db_xref="PDB:1FSX"
                     /db_xref="PDB:1G08"
                     /db_xref="PDB:1G09"
                     /db_xref="PDB:1G0A"
                     /db_xref="PDB:1HDA"
                     /db_xref="PDB:2QSP"
                     /db_xref="PDB:2QSS"
                     /db_xref="PDB:3CIU"
                     /db_xref="PDB:3PI8"
                     /db_xref="PDB:3PI9"
                     /db_xref="PDB:3PIA"
                     /db_xref="PDB:6IHX"
                     /db_xref="PDB:6II1"
                     /db_xref="UniProtKB/Swiss-Prot:P01966"
                     /protein_id="CAB56828.1"
                     /translation="MVLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYF
                     PHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLL
                     SHSLLVTLASHLPSDFTPAVHASLDKFLASVSTVLTSKYR"
     exon            <559..653
                     /gene="HBA2"
                     /allele="HBA2S"
                     /number=1
     intron          654..754
                     /gene="HBA2"
                     /allele="HBA2S"
                     /number=1
     exon            755..959
                     /gene="HBA2"
                     /allele="HBA2S"
                     /number=2
     intron          960..1063
                     /gene="HBA2"
                     /allele="HBA2S"
                     /number=2
     exon            1064..>1192
                     /gene="HBA2"
                     /allele="HBA2S"
                     /number=3
BASE COUNT          287 a          519 c          478 g          279 t
ORIGIN      
        1 gggaggaatt cgctgattac atgtgaacgg tgagccaagt gtgttactgg ctgcctctgg
       61 catggactag gcgcactcaa tcgcccgttc attcactgat actgcccaag tttaaaatgc
      121 ccagagtgtg ccaagcctag gtccggggtg gatagcacgg gctgacttac tcccttccgt
      181 tctcaagaca gctgacggac tcttacagga tgcaggagcg ggcatccacc cagctccaca
      241 atcccgcccc tgccacctgg cgcgaggcta ccactttcgg ggaaggtgga cgcagcgggc
      301 gggaagcaga cggtggaagc aagaaccccg ggtcagagtc caggtctccg tgggtgggtg
      361 agggaagcac ccatcgcccg gccgggcgca ggtcggacgc cgcgcgccct ctgcggtcca
      421 ggtccggccg cgcatgccgc gtgccagcca atgagcgcag cgcgggcggg cgtgcccctg
      481 gcgccgggag cataaaagct cgcgcactcg cagccccgca ctcttctggt ccagacccag
      541 actctgagag aacccaccat ggtgctgtct gccgccgaca agggcaatgt caaggccgcc
      601 tggggcaagg ttggcggcca cgctgcagag tatggcgcag aggccctgga gaggtgagca
      661 ccgcacttgc cccgagggga ccgggccgca cgccgggcgc gtccttgtcc cgggccgctc
      721 ggcctaagcc cggctttccc gcctcttcac ccaggatgtt cctgagcttc cccaccacca
      781 agacctactt cccccacttc gacctgagcc acggctccgc gcaggtcaag ggccacggcg
      841 cgaaggtggc cgccgcgctg accaaagcgg tggaacacct ggacgacctg cccggtgccc
      901 tgtctgaact gagtgacctg cacgctcaca agctgcgtgt ggacccggtc aacttcaagg
      961 tgagctcgcg ggcagggccg ggacagatct gggctagcgg ggcagagaat gcggcggcgc
     1021 ccccacccag cccccgcccc cctgacgtcc cctctctcgg cagcttctga gccactccct
     1081 gctggtgacc ctggcctccc acctccccag tgatttcacc cccgcggtcc acgcctccct
     1141 ggacaagttc ttggccagcg tgagcaccgt gctgacctcc aaataccgtt aagctggagc
     1201 ctcggcgacc cctaccctgg cctggagccc ccttgcgctc tgcgcactct cacctcctga
     1261 tctttgaata aagtctgagt gggctgcagt gtctgtagcc tcgggtctct gtgtccgcga
     1321 accggccggg gtgggcgtgg ttctcagtcc ctaagagtga gagggtggag gagggcgggg
     1381 agctaaggct gagggtccca gaatctgctg aaccaagttc ccctcctggg aagactttca
     1441 agggttctct ctgaggtggg gagtgctgaa atggccaccc tgttttgaaa tttttctgat
     1501 cccccttaaa catagttaga tgaaaacaaa agcaaaccac acaaataggc tcttccttgt
     1561 gca
//