LOCUS       AF315075                1038 bp    DNA     linear   HUM 14-DEC-2000
DEFINITION  Homo sapiens forkhead family transcription factor FOXL1 (FOXL1)
            gene, complete cds.
ACCESSION   AF315075
VERSION     AF315075.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Fang,J., Dagenais,S.L., Erickson,R.P., Arlt,M.F., Glynn,M.W.,
            Gorski,J.L., Seaver,L.H. and Glover,T.W.
  TITLE     Mutations in FOXC2 (MFH-1), a forkhead family transcription factor,
            are responsible for the hereditary lymphedema-distichiasis syndrome
  JOURNAL   Am. J. Hum. Genet. 67 (6), 1382-1388 (2000)
   PUBMED   11078474
REFERENCE   2  (bases 1 to 1038)
  AUTHORS   Fang,J., Dagenais,S.L., Erickson,R.P., Arlt,M.F., Glynn,M.W.,
            Gorski,J.L., Seaver,L.H. and Glover,T.W.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2000) Pediatrics and Human Genetics, University
            of Michigan, 4909 Buhl, Box 0618, Ann Arbor, MI 48109-0618, USA
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q24"
     gene            <1..>1038
                     /gene="FOXL1"
                     /gene_synonym="FKH6"
                     /gene_synonym="FREAC7"
     mRNA            <1..>1038
                     /gene="FOXL1"
                     /gene_synonym="FKH6"
                     /gene_synonym="FREAC7"
                     /product="forkhead family transcription factor FOXL1"
     CDS             1..1038
                     /gene="FOXL1"
                     /gene_synonym="FKH6"
                     /gene_synonym="FREAC7"
                     /note="winged helix/forkhead domain"
                     /codon_start=1
                     /product="forkhead family transcription factor FOXL1"
                     /protein_id="AAG40312.1"
                     /translation="MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRA
                     ETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLS
                     LNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAE
                     THQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDA
                     GDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPP
                     SGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFP
                     LQVPDTVLHFQ"
BASE COUNT          163 a          409 c          319 g          147 t
ORIGIN      
        1 atgagtcacc tcttcgatcc ccggctgcct gccctggccg cctcgcccat gctgtatctg
       61 tacggtcccg agagacccgg cctccctctg gccttcgccc ccgcggctgc tctagctgcc
      121 tcgggccggg ccgagacccc gcagaagcct ccctacagct acatcgcgct catcgccatg
      181 gcgatccagg acgcgcccga gcagagggtc acgctcaacg gcatctacca gttcatcatg
      241 gaccgcttcc ccttctacca cgacaaccgg cagggctggc agaacagcat ccgccacaac
      301 ctctcgctca acgactgctt cgtcaaggtg ccccgcgaga aagggcggcc gggcaagggc
      361 agctactgga cgctggaccc ccgctgcctg gacatgtttg agaacggcaa ctaccggcgc
      421 cggaagagga agcccaagcc gggccccggg gccccggagg ccaagaggcc ccgcgccgag
      481 acgcaccagc gcagcgcgga ggcgcagccg gaggcgggga gcggggcagg gggctcgggc
      541 cccgcaatct cccgcctgca ggcagcgccc gcgggcccct cgcccctcct ggacggcccc
      601 tctccgccgg cgcccctcca ctggccgggg accgcgtccc cgaacgagga cgctggtgac
      661 gctgcccagg gcgcagcggc cgtggcggtc ggccaggcag cgcgcacagg ggacggcccg
      721 gggtcccctc tgcgccccgc ctcccgcagc tctccgaaga gctccgacaa gtccaagagc
      781 ttcagcatag acagcatcct ggcgggaaag cagggccaga agccgccttc aggggacgaa
      841 ctcctagggg gtgccaagcc tgggcccggc ggccgtctgg gtgcctcgct cctggccgcc
      901 tcctccagcc tccgtccgcc tttcaacgct tccctgatgc tcgacccgca tgtccagggc
      961 ggcttttacc agctcgggat ccccttcctc tcttatttcc ccctgcaggt tcccgacacg
     1021 gtactccact tccagtaa
//