LOCUS       AF119835                 890 bp    mRNA    linear   HUM 29-MAR-1999
DEFINITION  Homo sapiens stem cell factor precursor, mRNA, complete cds.
ACCESSION   AF119835
VERSION     AF119835.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Blair,H.C., Julian,B.A., Cao,X., Jordan,S.E. and Dong,S.S.
  TITLE     Parathyroid hormone-regulated production of stem cell factor in
            human osteoblasts and osteoblast-like cells
  JOURNAL   Biochem. Biophys. Res. Commun. 255 (3), 778-784 (1999)
   PUBMED   10049787
REFERENCE   2  (bases 1 to 890)
  AUTHORS   Blair,H.C., Julian,B.A., Cao,X., Jordan,S.E. and Dong,S.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-1999) Pathology, University of Alabama School of
            Medicine, 701 S. 19th Street, Birmingham, AL 35294-0007, USA
FEATURES             Location/Qualifiers
     source          1..890
                     /db_xref="H-InvDB:HIT000070224"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MG631098"
                     /cell_type="osteoblast"
     CDS             143..880
                     /note="cell surface isoform lacking exon 6; similar to
                     murine KL-2"
                     /codon_start=1
                     /product="stem cell factor precursor"
                     /protein_id="AAD22048.1"
                     /translation="MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLV
                     ANLPKDYMITSKYVPGMDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIID
                     KLVNIVDDLVECVKENSSKDLKKSFRSPEPRFFTPEEFFRIFNRSIDAFKDFVVASET
                     SDCVVSSTLSPEKGKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTR
                     AVENIQINEEDNEISMLQEKEREFQEV"
BASE COUNT          263 a          175 c          204 g          248 t
ORIGIN      
        1 cagtggagag ggcgctgcgc tcgggctacc caatgcgtgg actatctgcc gccgctgttc
       61 gtgcaatatg ctggagctcc agaacagcta aacggagtcg ccacaccact gtttgtgctg
      121 gatcgcagcg ctgcctttcc ttatgaagaa gacacaaact tggattctca cttgcattta
      181 tcttcagctg ctcctattta atcctctcgt caaaactgaa gggatctgca ggaatcgtgt
      241 gactaataat gtaaaagacg tcactaaatt ggtggcaaat cttccaaaag actacatgat
      301 aacctcaaaa tatgtccccg ggatggatgt tttgccaagt cattgttgga taagcgagat
      361 ggtagtacaa ttgtcagaca gcttgactga tcttctggac aagttttcaa atatttctga
      421 aggcttgagt aattattcca tcatagacaa acttgtgaat atagtggatg accttgtgga
      481 gtgcgtgaaa gaaaactcat ctaaggatct aaaaaaatca ttcaggagcc cagaacccag
      541 gttctttact cctgaagaat tctttagaat ttttaataga tccattgatg ccttcaagga
      601 ctttgtagtg gcatctgaaa ctagtgactg tgtggtttct tcaacattaa gtcctgagaa
      661 agggaaggcc aaaaatcccc ctggagactc cagcctacac tgggcagcca tggcattgcc
      721 agcattgttt tctcttataa ttggctttgc ttttggtgcc ttatactgga agaagagaca
      781 gccaagtctt acaagggcag ttgaaaatat acaaattaat gaagaggata atgagataag
      841 tatgttgcaa gagaaagaga gagagtttca agaagtgtaa attgtggctt
//