LOCUS       AB021864                1546 bp    mRNA    linear   INV 05-AUG-1999
DEFINITION  Caenorhabditis elegans cmk-1 mRNA for Ca2+/calmodulin-dependent
            protein kinase I, complete cds.
ACCESSION   AB021864
VERSION     AB021864.1
KEYWORDS    .
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae;
            Peloderinae; Caenorhabditis.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Eto,K., Kimura,Y. and Tokumitsu,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-DEC-1998) to the DDBJ/EMBL/GenBank databases.
            Contact:Hiroshi Tokumitsu
            Heilix Research Institute, Inc., 3rd Department; 1532-3 Yana,
            Kisarazu, Chiba 292-0812, Japan
REFERENCE   2  
  AUTHORS   Eto,K., Takahashi,N., Kimura,Y., Masuho,Y., Arai,K., Muramatsu,M.
            and Tokumitsu,H.
  TITLE     Ca2+/calmodulin-dependent protein kinase cascade in Caenorhabditis
            elegans. Implication in transcriptional activation
  JOURNAL   J. Biol. Chem. 274, 22556-22562 (1999)
COMMENT     
FEATURES             Location/Qualifiers
     source          1..1546
                     /db_xref="taxon:6239"
                     /dev_stage="embryonic stage"
                     /mol_type="mRNA"
                     /organism="Caenorhabditis elegans"
                     /strain="Bristol N2"
     CDS             48..1094
                     /codon_start=1
                     /function="This gene encodes a Ca2+/calmodulin-dependent
                     protein kinase which is activated by C.elegans
                     Ca2+/calmodulin-dependent protein kinase kinase through
                     phosphorylation of Thr179."
                     /gene="cmk-1"
                     /note="similar to Rattus norvegicus
                     Ca2+/calmodulin-dependent protein kinase I, Accession
                     Number L26288."
                     /note="this gene is partially included in C.elegans
                     cosmid (K07A9)."
                     /product="Ca2+/calmodulin-dependent protein kinase I"
                     /protein_id="BAA82674.1"
                     /transl_table=1
                     /translation="MPLFKRRDGSGPAPNATIREKYDFRDVLGTGAFSKVFLAESKSD
                     AGQMYAVKCIDKKALKGKEESLENEIKVLRKLRHNNIVQLFDTYDEKQFVYLVMELVT
                     GGELFDRIVAKGSYTEQDASNLIRQVLEAVGFMHDNGVVHRDLKPENLLYYNQDEDSK
                     IMISDFGLSKTEDSGVMATACGTPGYVAPEVLQQKPYGKAVDVWSIGVIAYILLCGYP
                     PFYDESDANLFAQIIKGEYEFDAPYWDQISGSAKDFITHLMCCDPEARFTCQDALSHP
                     WISGNTAYTHDIHGTVAVHLKKSLAKRNWKKAYNAAAAIRQLQMLRLSSNSNRLQKQA
                     SQQQPEPPTPAFHA"
     polyA_site      1546
                     /note="24 A nucleotides"
BASE COUNT          428 a          386 c          332 g          400 t
ORIGIN      
        1 cacgagtttc ctttttctta ctcaacggct ccccctcgac gagcccaatg ccccttttta
       61 agcgacggga tgggagtggt cccgcgccga acgccacgat tcgggagaaa tatgattttc
      121 gtgatgtcct tgggacggga gctttttcga aggtgttcct agccgaatca aaaagtgatg
      181 ccggtcagat gtatgcagtc aaatgcattg acaaaaaagc actgaaggga aaagaagaat
      241 cactggaaaa cgagattaaa gttctgagga agctccgaca caacaatatt gttcaactat
      301 tcgatacata cgacgagaag cagtttgtgt atcttgtgat ggagctggtc accggtggag
      361 agcttttcga tagaattgtt gcaaaagggt cctacacgga acaggacgcg tcgaatctta
      421 ttagacaggt attggaagca gtcgggttta tgcacgacaa cggagtcgtc catcgtgacc
      481 tgaaacctga aaacctttta tattacaacc aagacgagga ctccaaaata atgatctcag
      541 attttggact ttcaaaaacc gaagattcag gagtaatggc tacagcgtgt ggaacaccgg
      601 gatacgtggc accagaggtc ctacagcaga aaccgtatgg aaaagcagtc gatgtttggt
      661 cgattggagt tatagcgtat attttgcttt gcggatatcc accattctac gacgagagcg
      721 atgcaaacct attcgcacag atcatcaaag gagaatacga gttcgacgcg ccctactggg
      781 atcagatttc cggttcggct aaagatttta tcacacactt aatgtgttgt gacccagaag
      841 cccgattcac gtgtcaggat gctctgtcac atccgtggat cagtggaaat accgcgtaca
      901 cacacgatat tcacggaact gtcgccgtac atcttaagaa gagtttggca aaacggaact
      961 ggaaaaaggc ttacaacgca gccgcagcaa tccgccagct tcaaatgctc cgtctctcct
     1021 caaatagcaa tcgcctacag aaacaagctt cacagcagca accggagccc cctacacccg
     1081 cttttcacgc ttgatgatgt ccttttaata cagtaatacg cttttgatct acccgacccc
     1141 ccaaagtctc agagtttcca cagaatttga actcccgaga aatcaatccg cgaaaaaaag
     1201 ggcggacaca cttttgcgga cgtggcttcg aattttctta ggctccgccc atttctccgg
     1261 gttttcgttt ccccggaaac tgttttcctt ggcaacactg ggactccccg tccacacacc
     1321 cgcgccgcgc aaacatgctc cactgtgatt tttttttgaa attgtttttt tcgttcgcaa
     1381 ctcaccccaa ccctcccttt ttacaattcc tcagtgtaca ttcctttttt ccaatttttt
     1441 cagccacagt acccccgccc ttcccccatg tacctttaaa atgtaatatt tgtgattttg
     1501 atctcgtgaa acaagaaaaa cactataaaa tgaattgttt tgtact
//