LOCUS       AB015231                2354 bp    mRNA    linear   ROD 20-OCT-1999
DEFINITION  Rattus norvegicus mRNA for stretch-inhibitable nonselective
            channel (SIC), complete cds.
ACCESSION   AB015231
VERSION     AB015231.3
KEYWORDS    .
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2354)
  AUTHORS   Suzuki,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUN-1998) to the DDBJ/EMBL/GenBank databases.
            Contact:Makoto Suzuki
            Jichi Medical School, Department of Pharmacology; Yakushiji,
            3311-1, Minamikawachi, Tochigi 329-04, Japan
REFERENCE   2  
  AUTHORS   Suzuki,M., Sato,J., Kutsuwada,K., Ooki,G. and Imai,M.
  TITLE     Cloning of a stretch-inhibitable nonselective cation channel
  JOURNAL   J. Biol. Chem. 274, 6330-6335 (1999)
COMMENT     Sequence updated (25-Jun-1999)
            
            Sequence updated (19-Oct-1999)
FEATURES             Location/Qualifiers
     source          1..2354
                     /db_xref="taxon:10116"
                     /mol_type="mRNA"
                     /organism="Rattus norvegicus"
                     /tissue_type="kidny"
     CDS             253..1839
                     /codon_start=1
                     /product="stretch-inhibitable nonselective channel (SIC)"
                     /protein_id="BAA34942.2"
                     /transl_table=1
                     /translation="MYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAY
                     ILQREIHEPECRHLSRKFTEWAYGAVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNR
                     HDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYKLKN
                     TVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLV
                     SVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFV
                     YLVFLFGFSTAVVTLIEDGKNNSLPMESTPHKCRGSACKPGNSYNSLYSTCLELFKFT
                     IGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVGQVSKESKHIWKL
                     QWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLG
                     IINEDPGKSEIYQYYGFSHTMGRLRRDRWSSVVPRVVELNKNSDTDEVVVPLDNLGNP
                     NCDGHQQGYAPKWRAEDAPL"
BASE COUNT          511 a          653 c          634 g          556 t
ORIGIN      
        1 gagctagagg cccaatcatc cagggactag cctcatttgt ggggctccac tggggatcct
       61 gtgttggctg caggtgagct gcccctgtcc ctggctgcgt gcaccaacca gctggccatt
      121 gtgaagttcc tgctgcagaa ctcctggcag cctgcagaca tcagcgcccg ggactcagtg
      181 ggcaacacgg tgcttcatgc cctggtggag gtggcagata acacagttga caacaccaag
      241 ttcgtgacaa gcatgtacaa cgagatcttg atcctggggg ccaaactcca ccccacgctg
      301 aagctggaag agatcaccaa caggaagggg ctcacgccac tggctctggc tgctagcagt
      361 gggaagatcg gggtcttggc ctacattctc cagagggaga tccatgaacc cgagtgccga
      421 cacctatcca ggaagttcac cgaatgggcc tatggggcag tgcactcctc cctttatgac
      481 ctgtcctgca ttgacacctg tgaaaagaac tcggttctgg aggtgatcgc ttacagcagc
      541 agtgagaccc ctaaccgtca tgacatgctt ctcgtggaac ccttgaaccg actcctacag
      601 gacaagtggg acagatttgt caagcgcatc ttctacttca acttcttcgt ctactgcttg
      661 tatatgatca tcttcaccgc ggctgcctac tatcggcctg tggaaggctt gcccccctat
      721 aagctgaaaa acaccgttgg ggactatttc cgagtcaccg gagagatctt gtctgtgtca
      781 ggaggagtct acttcttctt ccgagggatt caatatttcc tgcagaggcg accatccctc
      841 aagagtttgt ttgtggacag ctacagtgag atacttttct ttgtacagtc gctgttcatg
      901 ctggtgtctg tggtactgta cttcagccaa cgcaaggagt atgtggcttc catggtgttc
      961 tccctggcca tgggctggac caacatgctc tactataccc gaggattcca gcagatgggc
     1021 atctatgctg tcatgattga gaagatgatc ctcagagacc tgtgccggtt tatgttcgtc
     1081 tacctcgtgt tcttgtttgg attttccaca gctgtggtga cactgattga ggatgggaag
     1141 aataactctc tgcctatgga gtccacacca cacaagtgcc gggggtctgc ctgcaagcca
     1201 ggtaactctt acaacagcct gtattccaca tgtctggagc tgttcaagtt caccatcggc
     1261 atgggcgacc tggagttcac tgagaactat gacttcaagg ctgtcttcat catcctgctg
     1321 ctggcctatg taattctcac ctacatcctc cttctcaaca tgctcattgc tctcatgggt
     1381 gagaccgtgg gccaggtgtc caaggagagc aagcacatct ggaagctgca gtgggccacc
     1441 accatcctgg acatcgagcg ctccttccct gtgttcctga ggaaggcctt ccgctccgga
     1501 gagatggtga cagtgggcaa gagctcggat ggcactccag accgcaggtg gtgcttcagg
     1561 gtggacgagg tgaactggtc tcactggaac cagaacctgg gcatcattaa cgaggacccc
     1621 ggcaagagcg agatctacca gtactatggc ttctcccata ccatggggcg cctccgcagg
     1681 gatcgctggt cctcagtggt gccccgcgtg gtggagctga acaagaactc agacacagat
     1741 gaagtggtgg tccccctgga taacctaggg aaccccaact gtgacggcca ccagcaaggt
     1801 tatgctccca agtggagggc ggaggacgca ccactgtagg ggccatgcca gggctggggt
     1861 caatggccca ggcttggccc ttgctcccac ctacatttca gcatctgtcc tgtgtcttcc
     1921 cacacccaca ctacctcgga ggtgagggcc tctgtggaga ctctggggag gccccaggac
     1981 cctctggtcc ccacaaagac ttttgctctt atttctactc ctccccacat gggggacggg
     2041 gctcctggcc acctgtctca ctcccatgga gtcacctaag ccagctcagg cccctccact
     2101 cggcagggcc caggcccctg tcccttttgt gcatatttat tgctttcctc aggaaatgaa
     2161 tcacaggagt ttacctgcag ctggaacctg gccagggctg aggctatgca gggacatgca
     2221 gccctgaccc gctgcagatt tgacctgctg cagcccgggc tagggtgggt tttttgtatt
     2281 tgtagagatg gggctgttgg tgctcaataa atgtttgttt attttcggta aaaaaaaaaa
     2341 aaaaaaaaaa aaaa
//