LOCUS       WQZ29803.1              1211 aa    PRT              BCT 29-DEC-2023
DEFINITION  Helicobacter pylori DNA polymerase III subunit alpha protein.
ACCESSION   CP079244-1306
PROTEIN_ID  WQZ29803.1
SOURCE      Helicobacter pylori
  ORGANISM  Helicobacter pylori
            Bacteria; Campylobacterota; Epsilonproteobacteria;
            Campylobacterales; Helicobacteraceae; Helicobacter.
REFERENCE   1  (bases 1 to 1570870)
  AUTHORS   Thorell,K., Munoz-Ramirez,Z.Y., Wang,D., Sandoval-Motta,S., Boscolo
            Agostini,R., Ghirotto,S., Torres,R.C., Falush,D., Camargo,M.C. and
            Rabkin,C.S.
  CONSRTM   HpGP Research Network
  TITLE     The Helicobacter pylori Genome Project: insights into H. pylori
            population structure from analysis of a worldwide collection of
            complete genomes
  JOURNAL   Nat Commun 14 (1), 8184 (2023)
   PUBMED   38081806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570870)
  AUTHORS   Camargo,M.C. and Rabkin,C.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) IIB, National Cancer Institute, 9609
            Medical Center Dr., Rm. 6E110, Bethesda, MD 20892, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: HGAP v. 4
            Assembly Name          :: HpGP-TWN-021
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 2661x
            Sequencing Technology  :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 07/16/2021 08:12:09
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 1,497
            CDSs (total)                      :: 1,452
            Genes (coding)                    :: 1,391
            CDSs (with protein)               :: 1,391
            Genes (RNA)                       :: 45
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 44 of 61
            Pseudo Genes (incomplete)         :: 11 of 61
            Pseudo Genes (internal stop)      :: 18 of 61
            Pseudo Genes (multiple problems)  :: 12 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Helicobacter pylori"
                     /mol_type="genomic DNA"
                     /strain="HpGP-TWN-021"
                     /isolation_source="Biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:210"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.30 N 121.00 E"
                     /collected_by="Maria Camargo and Charles Rabkins"
     protein         /gene="dnaE"
                     /locus_tag="E5P95_06750"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017281734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /transl_table=11
BEGIN
        1 MKENKAFTHL HLHTEYSLLD GANKIKILAK RIKELGMKSV SVTDHGNMFG AIDFYTSMKK
       61 EGIKPIIGME AYIHNDDNLS SKETKQRFHL CLFAKNQEGY ENLMFLSSMA YLEGFYYFPR
      121 INKKLLREHS KGIIASSACL QGEVNYHLNT HNERNRKYGA KGYDEAKKIA CEYQEIFEDD
      181 FYLEIMRHGI LDQRFIDEQV IKMSLETGLK IIATNDTHYT MPNDAKAQEV AMCVAMGKTL
      241 NDKGRLKHSV HEFYIKSPEE MAKLFADIPE ALENTQEIAD KCVLEIDLKD DKKNPPTPPS
      301 FKFTKAYAQN EGLNFEDDAS YFAYKAREGL KERLVLVPKE KHDQYKERLE KEIEVITSMK
      361 FPGYMLIVWD FIRYAKEMGI PVGPGRGSAA GSLVAFALKI TDIDPLKYDL LFERFLNPER
      421 VSMPDIDTDF CQRRRKEIIE YMIEKYGKYN VAQVITFNKM LAKGVIRDVA RVLDMPYKEA
      481 DDFAKLIPNR LGITLKGYEK NGEFIEGAWE LEPKIKELVE SNELAKQVWE YSLNLENLNR
      541 NAGVHAAALV VDSQKELWHK TPLFASEKTG GIVTQYSMKY LEPVDLIKFD FLGLKTLTVI
      601 DDALKIIKTQ HKISVDFLSL DMDDPKVYKT IQSGDTVGIF QIESGMFQGL NKRLRPSSFE
      661 DIIAIIALGR PGPMESGMVD DFVNRKHGIE PIAYAFKELE PILKPTYGTI VYQEQVMQIV
      721 QTIGGFSLGE ADLIRRAMGK KDAQIMADNK AKFVEGAKNL GHDGQKAANL WDLIVKFAGY
      781 GFNKSHSAAY AMITFQTAYL KTYYKHEFMA AMLTSESNKI ESVACYIDEV RALEIEVMPP
      841 HINSSMQDFS VAEFKNQKGE LEKKIVFGLG AIKGVGGEPI KNIIEERAKG DYKSLEDFIS
      901 RVDFSKLTKK SLEPLVKSGS LDNLGYTRKT MLANLDLICD AGRAKDKANE MMQGGNSLFG
      961 AMDGGTKEQV ILDMIDLGEH DAKTLLECEY ETLGIHVSGN PLDEFKEEIK GFKNLVKSID
     1021 IEELEIGSQA YLLGKIMEVK KKIGKRSGKP YGTADILDRY GKFELMLFEK QLNALEELDI
     1081 NKPLVFKCKI EEQEEVARLR LFEILDLESA REVKIPKARY KDPEKQKEEV REIPPIEILA
     1141 ASSCSLAIVL ENDVKKEFLR QIKESALKHQ GKRPLYLIIK DKDKQFKIQS HLMVNEKIKD
     1201 DFKGLEWRDL A
//