LOCUS       WQZ29375.1              1328 aa    PRT              BCT 29-DEC-2023
DEFINITION  Helicobacter pylori vacuolating cytotoxin autotransporter protein.
ACCESSION   CP079244-846
PROTEIN_ID  WQZ29375.1
SOURCE      Helicobacter pylori
  ORGANISM  Helicobacter pylori
            Bacteria; Campylobacterota; Epsilonproteobacteria;
            Campylobacterales; Helicobacteraceae; Helicobacter.
REFERENCE   1  (bases 1 to 1570870)
  AUTHORS   Thorell,K., Munoz-Ramirez,Z.Y., Wang,D., Sandoval-Motta,S., Boscolo
            Agostini,R., Ghirotto,S., Torres,R.C., Falush,D., Camargo,M.C. and
            Rabkin,C.S.
  CONSRTM   HpGP Research Network
  TITLE     The Helicobacter pylori Genome Project: insights into H. pylori
            population structure from analysis of a worldwide collection of
            complete genomes
  JOURNAL   Nat Commun 14 (1), 8184 (2023)
   PUBMED   38081806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570870)
  AUTHORS   Camargo,M.C. and Rabkin,C.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) IIB, National Cancer Institute, 9609
            Medical Center Dr., Rm. 6E110, Bethesda, MD 20892, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: HGAP v. 4
            Assembly Name          :: HpGP-TWN-021
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 2661x
            Sequencing Technology  :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 07/16/2021 08:12:09
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 1,497
            CDSs (total)                      :: 1,452
            Genes (coding)                    :: 1,391
            CDSs (with protein)               :: 1,391
            Genes (RNA)                       :: 45
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 44 of 61
            Pseudo Genes (incomplete)         :: 11 of 61
            Pseudo Genes (internal stop)      :: 18 of 61
            Pseudo Genes (multiple problems)  :: 12 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Helicobacter pylori"
                     /mol_type="genomic DNA"
                     /strain="HpGP-TWN-021"
                     /isolation_source="Biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:210"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.30 N 121.00 E"
                     /collected_by="Maria Camargo and Charles Rabkins"
     protein         /locus_tag="E5P95_04315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /transl_table=11
BEGIN
        1 MELQQTHRKI NRPLVSLALV GLLVSITPQK SHAAFFTTVI IPAIVGGIAT GAAVGTVSGL
       61 LGWGLKQAEE ANKTPDKPDK VWRIQAGRGF NEFPNKEYDL YKSLLSSKID GGWDWGNAAR
      121 HYWVKGGQWN KLEVDMKDAV GTYKLSGLRN FTGGDLDVNM QKATLRLGQF NGNSFTSFKD
      181 NADRTTRVDF NAKNISIDNF LEINNRVGSG AGRKASSTVL TLQASEGITS SKNAEISLYD
      241 GATLNLASNS VKLMGNVWMG RLQYVGAYLA PSYSTINTSK VTGEVNFNHL TVGDRNAAQA
      301 GIIASKKTNI GTLDLWQSAG LNIIAPPEGG YKDKPNNTNS QSGAKNDKNE SAKNDKQESS
      361 QNNSNTQVIN PPNSGQKTEI QPTQVIDGPF AGAKDTVVNI NRINTNADGT IKIGGYTASL
      421 TTNAANLNIG KGGVNLSNQA SGRSLLVENL TGNITVDGAL MVNNQVGGYA LAGSSANFEF
      481 KAGVDTKNGT IAFNNDIHLG KAVNLRVDAH TAYFNGNIYL GKSTNLKVNG HSAHFKNIDA
      541 SKSDNGLNTS TLDFSGVTDK VNINKLTTAA TNVNIKNFDI KELVVTTRVQ SFGQYTIFGE
      601 NIGDKSRIGV VSLQTGYSPA YSGGVTFKSG KKLVIDELYH APWNYFDARN ITDVEINKKI
      661 LFGAPGNIAG KTGLMFNNLT LNSNASMDYG KDLDLTIQGH FTNNQGTMNL FVQDGRVATL
      721 NAGHQASMMF NNMIDNTTGF YKPLIKINNA QNLTKNKEHV LVRARNIDYN LVGVQGASYD
      781 NISASNTNLQ EQFKERLALY NNNNRMDICV VRKGNLNDIK ACGMAIGNQS MVNNPENYKY
      841 LEGKAWKNTG INKTANNTTI AVNVGNNSAP TSSESNTTNL PTNTPKNARF ASYALIKNAP
      901 FAHYSATPNL VAINKHDFGT IESVFELANR SGDIDTLYAH SGAQGRDLLQ TLLIDSHNAG
      961 YARTMIDATS ANEITKQLNT ATDALNNIAS LEHKTSGLQT LSLSNAMILN SRLVNLSRRH
     1021 TNNIDSFAQR LQALKDQKFA SLESAAEVLY QFAPKYEKPT NVWANAIGGA SLNSGGNTSL
     1081 YGTSAGVDAY LNQKVEAIVG GFGSYGYSSF NNQANSLNSG ANNANFGVYS RIFANQHEFD
     1141 FEAQGALGSD QSSLNFKSAL LRDLNQSYNY LAYGASTRAS YGYDFAFFRN ALVLKPSVGV
     1201 SYNHLGSTNF ESNSTHKTAL KNGASSQHLF NASANVEARY YYGDTSYFYM NAGVLQEFAN
     1261 FGSSNAVSLN TFKVNAVRNP LNTHARVMMG GELQLAKEVF LNLGFIYLHN LISNAGHFAS
     1321 NLGMRYSF
//