LOCUS       WQZ29279.1               852 aa    PRT              BCT 29-DEC-2023
DEFINITION  Helicobacter pylori bifunctional aconitate hydratase 2/
            2-methylisocitrate dehydratase protein.
ACCESSION   CP079244-745
PROTEIN_ID  WQZ29279.1
SOURCE      Helicobacter pylori
  ORGANISM  Helicobacter pylori
            Bacteria; Campylobacterota; Epsilonproteobacteria;
            Campylobacterales; Helicobacteraceae; Helicobacter.
REFERENCE   1  (bases 1 to 1570870)
  AUTHORS   Thorell,K., Munoz-Ramirez,Z.Y., Wang,D., Sandoval-Motta,S., Boscolo
            Agostini,R., Ghirotto,S., Torres,R.C., Falush,D., Camargo,M.C. and
            Rabkin,C.S.
  CONSRTM   HpGP Research Network
  TITLE     The Helicobacter pylori Genome Project: insights into H. pylori
            population structure from analysis of a worldwide collection of
            complete genomes
  JOURNAL   Nat Commun 14 (1), 8184 (2023)
   PUBMED   38081806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570870)
  AUTHORS   Camargo,M.C. and Rabkin,C.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) IIB, National Cancer Institute, 9609
            Medical Center Dr., Rm. 6E110, Bethesda, MD 20892, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: HGAP v. 4
            Assembly Name          :: HpGP-TWN-021
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 2661x
            Sequencing Technology  :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 07/16/2021 08:12:09
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 1,497
            CDSs (total)                      :: 1,452
            Genes (coding)                    :: 1,391
            CDSs (with protein)               :: 1,391
            Genes (RNA)                       :: 45
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 44 of 61
            Pseudo Genes (incomplete)         :: 11 of 61
            Pseudo Genes (internal stop)      :: 18 of 61
            Pseudo Genes (multiple problems)  :: 12 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Helicobacter pylori"
                     /mol_type="genomic DNA"
                     /strain="HpGP-TWN-021"
                     /isolation_source="Biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:210"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.30 N 121.00 E"
                     /collected_by="Maria Camargo and Charles Rabkins"
     protein         /gene="acnB"
                     /locus_tag="E5P95_03800"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001894116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /transl_table=11
BEGIN
        1 MKDFLEDYKK SVLERESEGI PPLPLNAKQV EAVVEILMKD PTNATFAKEL LIHRVSPGVD
       61 EGAKVKAEFL AKLSQKKLEC THISALEATT LLGTMLGGYN VEPLIMGLES QDKNIAKESA
      121 KALKTTLLVY GSFDKIVAMS KTNALAKEVL ESWANAEWFL NKEPLNECIE ACVFKIDGET
      181 NTDDLSPASD AFTRSDIPLH AKAMLKNRIE NYEQRIKAIK AKGVPVAYVG DVVGTGSSRK
      241 SATNSIMWHF GKDIPFVPNK RSGGIVIGGV IAPIFFATCE DSGALPIVAD VKDLKEGDMI
      301 KIYPYKGEIT LNDKVVSAFK LEPETLLDEV RASGRIPLII GRGLTNKARK FLGLGESEAF
      361 KKPSTPKSDA KGYTLAQKIV GHACGVKGIL PGTYCEPKVT TVGSQDTTGA MTRDEIKELA
      421 SLKFDAPFVL QSFCHTAAYP KPSDVSLHAT LPGFITQRGG VALHPGDGVI HTWLNRMGLP
      481 DTLGTGGDSH TRFPLGISFP AGSGLVAFAA VTGTMPLNMP ESVLVRFKGE MNPGITLRDL
      541 VNAIPYYAIK KGLLTVEKKG KINVFNGRIL EIEGLPDIKM EQAFELSDAS AERSAAACVV
      601 RLNKEPMIEY LKSNIKLIDE MIASGYEDKE TLKKRRDAMQ AWVDNPVLLE PDSNAQYAAV
      661 IEIDVAEITE PILACPNDPD DVATLSEVLA DTTGKRPHAI DEVFIGSCMT NIGHFRAFGE
      721 IVKNAPPSQA RLWVVPPSKM DEQELINEGY YAIFGAAGAR TEVPGCSLCM GNQARVRDNA
      781 VVFSTSTRNF DNRMGRGAKV YLGSAELGAA CALLGRIPTK EEYMNLVSEK LESQKDKIYR
      841 YMNFNLMENF RL
//