LOCUS VTR94366.1 528 aa PRT BCT 03-FEB-2020
DEFINITION Gemmata massiliana 2-isopropylmalate synthase : 2-isopropylmalate
synthase OS=Singulisphaera acidiphila (strain ATCC BAA-
1392 / DSM 18658 / VKM B-2454 / MOB10) GN=leuA PE=3 SV=
1: HMGL-like: LeuA_dimer protein.
ACCESSION LR593886-3667
PROTEIN_ID VTR94366.1
SOURCE Gemmata massiliana
ORGANISM Gemmata massiliana
Bacteria; Planctomycetes; Planctomycetia; Gemmatales; Gemmataceae;
Gemmata.
REFERENCE 1
AUTHORS
CONSRTM Science for Life Laboratories
JOURNAL Submitted (14-MAY-2019) to the INSDC. DEPARTMENT OF CELL AND
MOLECULAR BIOLOGY, Uppsala University, Molecular Evolution,
Biomedicinskt centrum (BMC), Husargatan 3, 752 37 Uppsala, Sweden
FEATURES Qualifiers
source /organism="Gemmata massiliana"
/chromosome="1"
/isolate="Soil9"
/mol_type="genomic DNA"
/isolation_source="soil"
/db_xref="taxon:1210884"
protein /locus_tag="SOIL9_33480"
/note="BLAST_uniprot:hit_4 ;
ACCESSION=tr|Q096Y3|Q096Y3_STIAD ;
ALN/Q_length_ratio=0.987 ; DESCRIPTION=2-isopropylmalate
synthase OS=Stigmatella aurantiaca (strain DW4/3-1)
GN=leuA PE=3 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.004"
/note="BLAST_uniprot:hit_2 ;
ACCESSION=tr|E8QZU8|E8QZU8_ISOPI ;
ALN/Q_length_ratio=0.972 ; DESCRIPTION=2-isopropylmalate
synthase OS=Isosphaera pallida (strain ATCC 43644 / DSM
9630 / IS1B) GN=leuA PE=3 SV=1 ; EVALUE=0.0 ;
Q/S_length_ratio=1.013"
/note="BLAST_uniprot:hit_12 ;
ACCESSION=tr|D5SN19|D5SN19_PLAL2 ;
ALN/Q_length_ratio=0.953 ; DESCRIPTION=2-isopropylmalate
synthase OS=Planctomyces limnophilus (strain ATCC 43296 /
DSM 3776 / IFAM 1008 / 290) GN=leuA PE=3 SV=1 ; EVALUE=0.0
; Q/S_length_ratio=1.013"
/note="BLAST_uniprot:hit_5 ;
ACCESSION=tr|Q2IJC1|Q2IJC1_ANADE ;
ALN/Q_length_ratio=0.953 ; DESCRIPTION=2-isopropylmalate
synthase OS=Anaeromyxobacter dehalogenans (strain 2CP-C)
GN=leuA PE=3 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.010"
/note="BLAST_uniprot:hit_7 ;
ACCESSION=tr|B8J824|B8J824_ANAD2 ;
ALN/Q_length_ratio=0.953 ; DESCRIPTION=2-isopropylmalate
synthase OS=Anaeromyxobacter dehalogenans (strain 2CP-1 /
ATCC BAA-258) GN=leuA PE=3 SV=1 ; EVALUE=0.0 ;
Q/S_length_ratio=1.010"
/note="BLAST_uniprot:hit_15 ;
ACCESSION=tr|M5TEG5|M5TEG5_9PLAN ;
ALN/Q_length_ratio=0.960 ; DESCRIPTION=2-isopropylmalate
synthase OS=Rhodopirellula sp. SWK7 GN=leuA PE=3 SV=1 ;
EVALUE=0.0 ; Q/S_length_ratio=0.989"
/note="BLAST_uniprot:hit_8 ;
ACCESSION=tr|D2R560|D2R560_PIRSD ;
ALN/Q_length_ratio=0.951 ; DESCRIPTION=2-isopropylmalate
synthase OS=Pirellula staleyi (strain ATCC 27377 / DSM
6068 / ICPB 4128) GN=leuA PE=3 SV=1 ; EVALUE=0.0 ;
Q/S_length_ratio=1.027"
/note="BLAST_uniprot:hit_14 ;
ACCESSION=tr|F0SS87|F0SS87_PLABD ;
ALN/Q_length_ratio=0.911 ; DESCRIPTION=2-isopropylmalate
synthase OS=Planctomyces brasiliensis (strain ATCC 49424 /
DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN=leuA
PE=3 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.031"
/note="BLAST_uniprot:hit_10 ;
ACCESSION=tr|S9R6F5|S9R6F5_9DELT ;
ALN/Q_length_ratio=0.958 ; DESCRIPTION=2-isopropylmalate
synthase OS=Cystobacter fuscus DSM 2262 GN=leuA PE=3 SV=1
; EVALUE=0.0 ; Q/S_length_ratio=1.004"
/note="BLAST_uniprot:hit_9 ;
ACCESSION=tr|M5R9H3|M5R9H3_9PLAN ;
ALN/Q_length_ratio=0.955 ; DESCRIPTION=2-isopropylmalate
synthase OS=Rhodopirellula maiorica SM1 GN=leuA PE=3 SV=1
; EVALUE=0.0 ; Q/S_length_ratio=1.010"
/note="BLAST_uniprot:hit_3 ;
ACCESSION=tr|A7HBI1|A7HBI1_ANADF ;
ALN/Q_length_ratio=0.951 ; DESCRIPTION=2-isopropylmalate
synthase OS=Anaeromyxobacter sp. (strain Fw109-5) GN=leuA
PE=3 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.011"
/note="BLAST_uniprot:hit_13 ;
ACCESSION=tr|A6CAS9|A6CAS9_9PLAN ;
ALN/Q_length_ratio=0.947 ; DESCRIPTION=2-isopropylmalate
synthase OS=Planctomyces maris DSM 8797 GN=leuA PE=3 SV=1
; EVALUE=0.0 ; Q/S_length_ratio=1.041"
/note="BLAST_uniprot:hit_11 ;
ACCESSION=tr|A3ZTL4|A3ZTL4_9PLAN ;
ALN/Q_length_ratio=0.956 ; DESCRIPTION=2-isopropylmalate
synthase OS=Blastopirellula marina DSM 3645 GN=leuA PE=3
SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.033"
/note="BLAST_uniprot:hit_6 ;
ACCESSION=tr|B4UAM9|B4UAM9_ANASK ;
ALN/Q_length_ratio=0.953 ; DESCRIPTION=2-isopropylmalate
synthase OS=Anaeromyxobacter sp. (strain K) GN=leuA PE=3
SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.010"
/note="BLAST_uniprot:hit_1 ;
ACCESSION=tr|L0DPM5|L0DPM5_SINAD ;
ALN/Q_length_ratio=0.962 ; DESCRIPTION=2-isopropylmalate
synthase OS=Singulisphaera acidiphila (strain ATCC
BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=leuA PE=3
SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.010"
/note="Pfam_scan:hit_1 (18..257);
Pfam:PF00682.14:HMGL-like;
Pfam_type:Family;HMM_aln_Length:235; HMM_Length:237;
EVALUE:1.6e-85; BITSCORE: 286.5"
/note="Pfam_scan:hit_2 (374..506);
Pfam:PF08502.5:LeuA_dimer;
Pfam_type:Domain;HMM_aln_Length:131; HMM_Length:133;
EVALUE:3e-30; BITSCORE: 104.7"
/note="GO_domain:GO:0016746"
/note="GO_domain:GO:0006520"
/note="GO_domain:GO:0009058"
/note="Enzyme_Code:EC:2.3.3.13"
BEGIN
1 MPVPTDPNRV IIFDTTLRDG EQSPGCSMNL PEKLEMARAL ADLGVDVIEA GFPIASPGDF
61 ESVQAIARQI HGPIIAGLAR CNPTDIDRAA DAVKDASKPR IHVFLATSAI HREFKLRMTS
121 EEVAKRAVEG VKRARDRCAD VEFSPEDAAR TELDFLAEVV ERAIEAGATT LNIPDTVGYA
181 VPTHYAAIIR HLKQHVRGID KCVLSVHCHN DLGLAVANSL AALGEGARQV ECTINGIGER
241 AGNTSLEEVV MALHTRSDFY KLATGINTRH LYPVSRKLAH ITGQQVQRNK AIVGQNAFAH
301 EAGIHQDGML KERSTYEIMK PEDVGIPQTE LVLGKHSGRH ALKQRVTDLG YRLTEEQLNR
361 VFEEFKKLAD KKKEIYDADI EALAENQLQA GTGNLWTLVG FTSTAGTGSQ TSAAVTLKHL
421 DGTVRRDAAI GNGPIDALIK AINRITGAEV KVVDYRVRSV SQDMDALGEV NIEIEHAGKR
481 SRARAVSLDV VEASALAYLE VVNRVASRLL RDRLKPTDDV PTEVVPAS
//