LOCUS CDQ51224.1 296 aa PRT BCT 04-FEB-2016 DEFINITION Vibrio anguillarum Siroheme synthase 1 (uroporphyrin-III c-methyltransferase) protein. ACCESSION LK021130-2306 PROTEIN_ID CDQ51224.1 SOURCE Vibrio anguillarum ORGANISM Vibrio anguillarum Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio. REFERENCE 1 (bases 1 to 3119695) AUTHORS Holm K. JOURNAL Submitted (26-MAR-2014) to the INSDC. Norstruct, Dept of Chemistry, University of Tromso, Science Park 3, NO-9037 Tromso, NORWAY. REFERENCE 2 AUTHORS Holm K.O., Nilsson K., Hjerde E., Willassen N.P., Milton D.L. TITLE Complete genome sequence of Vibrio anguillarum strain NB10, a virulent isolate from the Gulf of Bothnia JOURNAL Stand Genomic Sci 10, 60-60(2015). PUBMED 26380645 FEATURES Qualifiers source /organism="Vibrio anguillarum" /chromosome="1" /host="Rainbow trout" /strain="NB10" /mol_type="genomic DNA" /geo_loc_name="Sweden:Baltic Sea, Norrbyn Umeaa" /isolation_source="clinical isolate, Rainbow trout" /serovar="O1" /db_xref="taxon:55601" protein /transl_table=11 /gene="cysG" /locus_tag="VANGNB10_cI2312c" /old_locus_tag="TVA0061" /function="Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)." /EC_number="2.1.1.107" /note="user locus_tag: VANGcI2312c" BEGIN 1 MSTTETISQL PIKGPRLVAV NNDALASSAP SYVKSQLTCG EVALIGAGPG DPELLTLKAL 61 SFLQQADVVL YDYLVSDEIM ALVPSDTILV CVGKRAGHHS VPQEKTNQLL IDFAQQGYKV 121 VRIKGGDPFM FGRGGEELEV LFDAGVKFQV IPGITAAAGA TAYAGIPLTH RDYAQSALFV 181 TGHLKAENDD MDWSTLARGN QTLVIYMGLM KSSYIQQQLI EHGRQANTPI AIIERGTQRS 241 QKVFKGQLSD LSQLAVQAQA PALIVVGEVV GEVVALSEKL HWFGEQPAQQ NQVNYA //