LOCUS       CDQ49813.1               676 aa    PRT              BCT 04-FEB-2016
DEFINITION  Vibrio anguillarum UvrABS system protein B protein.
ACCESSION   LK021130-895
PROTEIN_ID  CDQ49813.1
SOURCE      Vibrio anguillarum
  ORGANISM  Vibrio anguillarum
            Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
            Vibrionaceae; Vibrio.
REFERENCE   1  (bases 1 to 3119695)
  AUTHORS   Holm K.
  JOURNAL   Submitted (26-MAR-2014) to the INSDC. Norstruct, Dept of Chemistry,
            University of Tromso, Science Park 3, NO-9037 Tromso, NORWAY.
REFERENCE   2
  AUTHORS   Holm K.O., Nilsson K., Hjerde E., Willassen N.P., Milton D.L.
  TITLE     Complete genome sequence of Vibrio anguillarum strain NB10, a
            virulent isolate from the Gulf of Bothnia
  JOURNAL   Stand Genomic Sci 10, 60-60(2015).
   PUBMED   26380645
FEATURES             Qualifiers
     source          /organism="Vibrio anguillarum"
                     /chromosome="1"
                     /host="Rainbow trout"
                     /strain="NB10"
                     /mol_type="genomic DNA"
                     /geo_loc_name="Sweden:Baltic Sea, Norrbyn Umeaa"
                     /isolation_source="clinical isolate, Rainbow trout"
                     /serovar="O1"
                     /db_xref="taxon:55601"
     protein         /transl_table=11
                     /gene="uvrB"
                     /locus_tag="VANGNB10_cI0899"
                     /old_locus_tag="TVA1921"
                     /function="The UvrABC repair system catalyzes the
                     recognition and processing of DNA lesions. A damage
                     recognition complex composed of 2 uvrA and 2 uvrB subunits
                     scans DNA for abnormalities. Upon binding of the
                     uvrA(2)B(2) complex to a putative damaged site, the DNA
                     wraps around one uvrB monomer. DNA wrap is dependent on
                     ATP binding by uvrB and probably causes local melting of
                     the DNA helix, facilitating insertion of uvrB beta-hairpin
                     between the DNA strands. Then uvrB probes one DNA strand
                     for the presence of a lesion. If a lesion is found the
                     uvrA subunits dissociate and the uvrB-DNA preincision
                     complex is formed. This complex is subsequently bound by
                     uvrC and the second uvrB is released. If no lesion is
                     found, the DNA wraps around the other uvrB subunit that
                     will check the other stand for damage (By similarity)."
                     /note="user locus_tag: VANGcI0899"
                     /note="Similar to Escherichia coli (strain K12) uvrb
                     recname: full=uvrabc system protein b short=protein uvrb
                     altname: full=excinuclease abc subunit b UniProt:P0A8F8
                     (673 aa) fasta scores: E()=3.1e-196, 75.8% id in 677 aa"
BEGIN
        1 MSKTFELVSG YQPSGDQPTA IKQLFDGLDA GLAHQTLLGV TGSGKTFTLA NVIAKAQRPV
       61 ILLAPNKTLA AQLYGEMKSF FPNNAVEYFV SYYDYYQPEA YVPTTDTFIE KDSSINSHIE
      121 QMRLSATKAL LERKDAIIVA SVSAIYGLGD PDSYLKMMLH VRRGDVMDQR DIIRRLAELQ
      181 YTRNDMAFER GQFRVRGEVI DIFPAESDYA AVRVEMFDDE VDCISLFDPL TGAMIQRDLP
      241 RYTIYPKTHY VTPRERIVDA IEHIKEELRT RQAYLLENNK LLEEQRISQR TQFDIEMMNE
      301 LGFCSGIENY SRYLSGRKEG EPPPTLFDYL PHDGLLIIDE SHVTVPQIGA MFKGDRSRKE
      361 TLVEFGFRLP SALDNRPLKF EEFESLAPQT IFVSATPGNY ELEKSAGQIV DQVVRPTGLL
      421 DPVLEVRPVA TQVDDVLSEI RIRSAKDERV LITTLTKRMA EDLTEYLHEH GVKVRYLHSD
      481 IDTVERVEII RDLRLGEFDV LVGINLLREG LDMPEVSLVA ILDADKEGFL RSERSLIQTI
      541 GRAARNIEGK AILYADRITN SMKKAMDETD RRREKQQAHN EEQGITPQAL KRNVKDIMEL
      601 GDITKSKQQR MNKQVPLSKV AESSQTYEIF TPLQLEKEIA KLEGLMYKHA QNLEFELAAE
      661 KRDQIEKLRQ QFITNS
//