LOCUS CAQ85791.1 367 aa PRT BCT 27-FEB-2015 DEFINITION Photorhabdus asymbiotica rod shape-determining protein mreb protein. ACCESSION FM162591-3698 PROTEIN_ID CAQ85791.1 SOURCE Photorhabdus asymbiotica ORGANISM Photorhabdus asymbiotica Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Morganellaceae; Photorhabdus. REFERENCE 1 (bases 1 to 5064808) AUTHORS Crossman L.C. JOURNAL Submitted (21-MAY-2008) to the INSDC. Crossman L.C., Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, Cambridgeshire, CB10 1SA, UNITED KINGDOM. REFERENCE 2 AUTHORS Wilkinson P., Waterfield N.R., Crossman L., Corton C., Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L., Doggett J., Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Arrowsmith C., Churcher C., Harris D., Thompson N.R., Quail M., Parkhill J., Ffrench-Constant R.H. TITLE Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens JOURNAL BMC Genomics 10(1), 302-302(2009). PUBMED 19583835 FEATURES Qualifiers source /organism="Photorhabdus asymbiotica" /isolate="ATCC43949" /mol_type="genomic DNA" /db_xref="taxon:291112" protein /transl_table=11 /gene="mreB" /locus_tag="PAU_03703" /old_locus_tag="PAT0547" /note="the gene products localise close to the cell surface, forming filamentous helical structures. Many homologues have been found in diverse bacterial groups, suggesting a common ancestor . The crystal structure of MreB from Thermotoga maritima has been resolved using X-ray crystallography . It consists of 19 beta-strands and 15 alpha- helices, and shows remarkable structural similarity to eukaryotic actin. MreB crystals also contain proto-filaments, with individual proteins assembling into polymers like F-actin, in the same orientation. It is hypothesised therefore, that MreB was the forerunner of actin in early eukaryotes ." /db_xref="EnsemblGenomes-Gn:PAU_03703" /db_xref="EnsemblGenomes-Tr:CAQ85791" /db_xref="GOA:C7BLT5" /db_xref="InterPro:IPR004753" /db_xref="UniProtKB/TrEMBL:C7BLT5" /inference="similar to DNA sequence:INSD:BX571872" /inference="similar to DNA sequence:INSD:BA000007" BEGIN 1 MVGRVDGFHS VPSLQDYPFA MFKKFRGMFS NDLSIDLGTA NTLIYVKGQG IVLNEPSVVA 61 IRQDRAGSSK SVAAVGQEAK QMLGRTPGNI AAIRPMKDGV IADFYVTEKM LQHFIKQVHS 121 NSFMRPSPRV LVCVPVGATQ VERRAIRESA LSAGAREVFL IEEPMSAAIG AGLPVSEATG 181 SMVVDIGGGT TEVAVISLNG VVYSSSVRIG GDRFDEAIIN YVRRNYGALI GEATAERIKH 241 TIGSAYPGDE MLEIEVRGRN LAEGVPRGFT LNSNEILEAL QEPLTGIVSA VMVALEQCPP 301 ELASDISERG MILTGGGALL RNLDRLLIEE TGIPVIVAED PLTCVARGGG KALEMIDMHG 361 GELFSEE //