LOCUS       APA96610.1               158 aa    PRT              BCT 30-JAN-2018
DEFINITION  Nocardia seriolae SsrA-binding protein protein.
ACCESSION   CP017839-2519
PROTEIN_ID  APA96610.1
SOURCE      Nocardia seriolae
  ORGANISM  Nocardia seriolae
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Genome sequence of Nocardia seriolae strain EM150506, isolated from
            Anguila japonica
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8304518)
  AUTHORS   Han,H.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2016) Pathology Research Division, National
            Institute of Fisheries Science, #216, Gijanghaean-ro, Gijang-eup,
            Gijang-gun, Busan 46083, South Korea
COMMENT     DNA/bacteria available from National Institute of Fisheries Science
            (NIFS) in South Korea.
            
            ##Genome-Assembly-Data-START##
            Assembly Method       :: SMRT analysis v. 2.3.0
            Genome Coverage       :: 156x
            Sequencing Technology :: PacBio
            ##Genome-Assembly-Data-END##
FEATURES             Qualifiers
     source          /organism="Nocardia seriolae"
                     /mol_type="genomic DNA"
                     /strain="EM150506"
                     /host="Anguilla japonica"
                     /db_xref="taxon:37332"
                     /geo_loc_name="South Korea"
                     /collection_date="2015-05-06"
     protein         /locus_tag="NS506_02547"
                     /function="Cytoplasm; RNA-binding."
                     /note="Required for rescue of stalled ribosomes mediated
                     by trans-translation. Binds to transfer-messenger RNA
                     (tmRNA), required for stable association of tmRNA with
                     ribosomes. tmRNA and SmpB together mimic tRNA shape,
                     replacing the anticodon stem-loop with SmpB. tmRNA is
                     encoded by the ssrA gen; the 2 termini fold to resemble
                     tRNA(Ala) and it encodes a 'tag peptide', a short internal
                     open reading frame. During trans-translation Ala-
                     aminoacylated tmRNA acts like a tRNA, entering the A-site
                     of stalled ribosomes, displacing the stalled mRNA. The
                     ribosome then switches to translate the ORF on the tmRN;
                     the nascent peptide is terminated with the 'tag peptide'
                     encoded by the tmRNA and targeted for degradation. The
                     ribosome is freed to recommence translation, which seems
                     to be the essential function of trans- translation;
                     Belongs to the SmpB family"
                     /transl_table=11
                     /db_xref="UniProtKB/Swiss-Prot:Q5YR60"
BEGIN
        1 MKEKGRKVIA SNKKAKHNYS IIETYEAGVA LVGTEVKSLR EGKASLVDAY ASIDDGEVWL
       61 RGLHVPEYGH GTWTNHAPRR TRKLLLHRRE IDKLLGKTKE SSLTLVPLSM YFSDGKVKVE
      121 LALAKGKQDY DKRQDLARRD TEREITRELG RRIKGMRG
//