LOCUS       WQZ30546.1               828 aa    PRT              BCT 29-DEC-2023
DEFINITION  Helicobacter pylori DNA topoisomerase (ATP-hydrolyzing)
            subunit A protein.
ACCESSION   CP079244-667
PROTEIN_ID  WQZ30546.1
SOURCE      Helicobacter pylori
  ORGANISM  Helicobacter pylori
            Bacteria; Campylobacterota; Epsilonproteobacteria;
            Campylobacterales; Helicobacteraceae; Helicobacter.
REFERENCE   1  (bases 1 to 1570870)
  AUTHORS   Thorell,K., Munoz-Ramirez,Z.Y., Wang,D., Sandoval-Motta,S., Boscolo
            Agostini,R., Ghirotto,S., Torres,R.C., Falush,D., Camargo,M.C. and
            Rabkin,C.S.
  CONSRTM   HpGP Research Network
  TITLE     The Helicobacter pylori Genome Project: insights into H. pylori
            population structure from analysis of a worldwide collection of
            complete genomes
  JOURNAL   Nat Commun 14 (1), 8184 (2023)
   PUBMED   38081806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570870)
  AUTHORS   Camargo,M.C. and Rabkin,C.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2021) IIB, National Cancer Institute, 9609
            Medical Center Dr., Rm. 6E110, Bethesda, MD 20892, USA
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            ##Genome-Assembly-Data-START##
            Assembly Method        :: HGAP v. 4
            Assembly Name          :: HpGP-TWN-021
            Genome Representation  :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 2661x
            Sequencing Technology  :: PacBio Sequel II
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 07/16/2021 08:12:09
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 5.2
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Genes (total)                     :: 1,497
            CDSs (total)                      :: 1,452
            Genes (coding)                    :: 1,391
            CDSs (with protein)               :: 1,391
            Genes (RNA)                       :: 45
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 36
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 44 of 61
            Pseudo Genes (incomplete)         :: 11 of 61
            Pseudo Genes (internal stop)      :: 18 of 61
            Pseudo Genes (multiple problems)  :: 12 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Helicobacter pylori"
                     /mol_type="genomic DNA"
                     /strain="HpGP-TWN-021"
                     /isolation_source="Biopsy"
                     /host="Homo sapiens"
                     /db_xref="taxon:210"
                     /geo_loc_name="Taiwan"
                     /lat_lon="23.30 N 121.00 E"
                     /collected_by="Maria Camargo and Charles Rabkins"
     protein         /gene="gyrA"
                     /locus_tag="E5P95_03405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015085797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /transl_table=11
BEGIN
        1 MQDNLINETK NIVEVGIDSS IEESYLAYSM SVIIGRALPD ARDGLKPVHR RILYAMHELG
       61 LTSKVAYKKS ARIVGDVIGK YHPHGDNAVY DALVRMAQDF SMRLELVDGQ GNFGSIDGDN
      121 AAAMRYTEAR MTKASEEILR DIDKDTIDFV PNYDDTLKEP DILPSRLPNL LVNGANGIAV
      181 GMATSIPPHR IDEIIDALVH VLENPNAGLD EILEFVKGPD FPTGGIIYGK AGIIEAYKTG
      241 RGRVKVRAKV HVEKTKNKEI IVLDEMPFQT NKAKLVEQIS DLVREKQIEG ISEVRDESDR
      301 EGIRVVIELK RDAMSEIVLN HLYKLTTMET TFSIILLAIY NKEPKIFTLL ELLRLFLNHR
      361 KTIIIRRTIF ELEKAKARAH ILEGYLIALD NIDEIVRLIK TSQSPEAAKN ALMERFTLSE
      421 IQSKAILEMR LQRLTGLERD KIKEEYQNLL ELISDLNGIL KSEDRLNEVV KTELLEVKEQ
      481 FSSQRRTEIQ EAYENIDIED LIANEPMVVS MSYKGYVKRV DLKAYERQNR GGKGKLSGNT
      541 YEDDFIENFF VANTHDILLF ITNKGQLYHL KVYKIPEASR IAMGKAIVNL ISLAPDEKIM
      601 ATLSTKDFSD ERSLAFFTKN GVVKRTNLSE FGSNRSYSGI RAIVLDEGDE LVSAKIVDKN
      661 AKHLLIASYL GIFIKFPLED VREIGRTTRG VIGIRLNEND FVVGAVVINN DGNKLLSVSE
      721 NGLGKQTLAE AYREQSRGGK GIIGMKLTQK TGNLVSVISV DDENLDLMIL TTSAKMIRVS
      781 IKDIKETIRR NTSGVKLIDT ADKVVYANSC PKEEEPENLE NPPTQLFE
//