LOCUS       VTS02463.1              1199 aa    PRT              BCT 03-FEB-2020
DEFINITION  Gemmata massiliana methionine synthase : Methionine synthase
            OS=Gloeobacter kilaueensis JS1 GN=metH PE=4 SV=1: S-methyl_trans:
            Pterin_bind: B12-binding_2: B12-binding: Met_synt_B12
            protein.
ACCESSION   LR593886-8084
PROTEIN_ID  VTS02463.1
SOURCE      Gemmata massiliana
  ORGANISM  Gemmata massiliana
            Bacteria; Planctomycetes; Planctomycetia; Gemmatales; Gemmataceae;
            Gemmata.
REFERENCE   1
  AUTHORS   
  CONSRTM   Science for Life Laboratories
  JOURNAL   Submitted (14-MAY-2019) to the INSDC. DEPARTMENT OF CELL AND
            MOLECULAR BIOLOGY, Uppsala University, Molecular Evolution,
            Biomedicinskt centrum (BMC), Husargatan 3, 752 37 Uppsala, Sweden
FEATURES             Qualifiers
     source          /organism="Gemmata massiliana"
                     /chromosome="1"
                     /isolate="Soil9"
                     /mol_type="genomic DNA"
                     /isolation_source="soil"
                     /db_xref="taxon:1210884"
     protein         /locus_tag="SOIL9_75080"
                     /note="BLAST_uniprot:hit_4 ;
                     ACCESSION=tr|D6YBK6|D6YBK6_THEBD ;
                     ALN/Q_length_ratio=0.956 ; DESCRIPTION=Methionine synthase
                     OS=Thermobispora bispora (strain ATCC 19993 / DSM 43833 /
                     CBS 139.67 / JCM 10125 / NBRC 14880 / R51) GN=Tbis_1854
                     PE=4 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.039"
                     /note="BLAST_uniprot:hit_2 ;
                     ACCESSION=tr|Q7NND4|Q7NND4_GLOVI ;
                     ALN/Q_length_ratio=0.996 ;
                     DESCRIPTION=5-methyltetrahydrofolate--homocysteine
                     S-methyltransferase OS=Gloeobacter violaceus (strain PCC
                     7421) GN=metH PE=4 SV=1 ; EVALUE=0.0 ;
                     Q/S_length_ratio=1.003"
                     /note="BLAST_uniprot:hit_12 ;
                     ACCESSION=tr|F5UL57|F5UL57_9CYAN ;
                     ALN/Q_length_ratio=0.972 ; DESCRIPTION=Methionine synthase
                     OS=Microcoleus vaginatus FGP-2 GN=MicvaDRAFT_4859 PE=4
                     SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.014"
                     /note="BLAST_uniprot:hit_5 ;
                     ACCESSION=tr|F8K2K8|F8K2K8_STREN ;
                     ALN/Q_length_ratio=0.952 ; DESCRIPTION=Methionine synthase
                     OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 /
                     JCM 4925 / NBRC 14057 / NRRL 8057) GN=metH PE=4 SV=1 ;
                     EVALUE=0.0 ; Q/S_length_ratio=1.027"
                     /note="BLAST_uniprot:hit_7 ;
                     ACCESSION=tr|D2ATZ7|D2ATZ7_STRRD ;
                     ALN/Q_length_ratio=0.956 ; DESCRIPTION=Methionine synthase
                     OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021
                     / JCM 3005 / NI 9100) GN=Sros_5917 PE=4 SV=1 ; EVALUE=0.0
                     ; Q/S_length_ratio=1.039"
                     /note="BLAST_uniprot:hit_15 ;
                     ACCESSION=tr|A0A059W479|A0A059W479_STRA9 ;
                     ALN/Q_length_ratio=0.959 ;
                     DESCRIPTION=5-methyltetrahydrofolate:homocysteine
                     S-methyltransferase OS=Streptomyces albulus GN=DC74_2127
                     PE=4 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.026"
                     /note="BLAST_uniprot:hit_8 ;
                     ACCESSION=tr|K9XGR8|K9XGR8_9CHRO ;
                     ALN/Q_length_ratio=1.004 ; DESCRIPTION=Methionine synthase
                     (B12-dependent) OS=Gloeocapsa sp. PCC 7428 GN=Glo7428_2798
                     PE=4 SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=0.994"
                     /note="BLAST_uniprot:hit_14 ;
                     ACCESSION=tr|M3C6B9|M3C6B9_STRMB ;
                     ALN/Q_length_ratio=0.952 ; DESCRIPTION=Methionine synthase
                     OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847
                     GN=H340_16321 PE=4 SV=1 ; EVALUE=0.0 ;
                     Q/S_length_ratio=1.028"
                     /note="BLAST_uniprot:hit_10 ;
                     ACCESSION=tr|I3TIS7|I3TIS7_TISMK ;
                     ALN/Q_length_ratio=0.964 ;
                     DESCRIPTION=5-methyltetrahydrofolate--homocysteine
                     methyltransferase OS=Tistrella mobilis (strain
                     KA081020-065) GN=metH PE=4 SV=1 ; EVALUE=0.0 ;
                     Q/S_length_ratio=1.026"
                     /note="BLAST_uniprot:hit_9 ;
                     ACCESSION=tr|Q8DK43|Q8DK43_THEEB ;
                     ALN/Q_length_ratio=0.975 ;
                     DESCRIPTION=5-methyltetrahydrofolate--homocysteine
                     methyltransferase OS=Thermosynechococcus elongatus (strain
                     BP-1) GN=metH PE=4 SV=1 ; EVALUE=0.0 ;
                     Q/S_length_ratio=1.020"
                     /note="BLAST_uniprot:hit_3 ;
                     ACCESSION=tr|W2F226|W2F226_9ACTO ;
                     ALN/Q_length_ratio=0.956 ; DESCRIPTION=Methionine synthase
                     OS=Microbispora sp. ATCC PTA-5024 GN=MPTA5024_00845 PE=4
                     SV=1 ; EVALUE=0.0 ; Q/S_length_ratio=1.039"
                     /note="BLAST_uniprot:hit_13 ;
                     ACCESSION=tr|G7Z3X0|G7Z3X0_AZOL4 ;
                     ALN/Q_length_ratio=0.966 ; DESCRIPTION=B12-dependent
                     homocysteine-N5-methyltetrahydrofolate transmethylase
                     OS=Azospirillum lipoferum (strain 4B) GN=metH PE=4 SV=1 ;
                     EVALUE=0.0 ; Q/S_length_ratio=1.031"
                     /note="BLAST_uniprot:hit_11 ;
                     ACCESSION=tr|A0A060DFH0|A0A060DFH0_AZOBR ;
                     ALN/Q_length_ratio=0.966 ; DESCRIPTION=Methionine synthase
                     OS=Azospirillum brasilense GN=ABAZ39_05285 PE=4 SV=1 ;
                     EVALUE=0.0 ; Q/S_length_ratio=1.031"
                     /note="BLAST_uniprot:hit_6 ;
                     ACCESSION=tr|K9TY09|K9TY09_9CYAN ;
                     ALN/Q_length_ratio=0.974 ; DESCRIPTION=Methionine synthase
                     (B12-dependent) OS=Chroococcidiopsis thermalis PCC 7203
                     GN=Chro_2226 PE=4 SV=1 ; EVALUE=0.0 ;
                     Q/S_length_ratio=1.018"
                     /note="BLAST_uniprot:hit_1 ;
                     ACCESSION=tr|U5QE48|U5QE48_9CYAN ;
                     ALN/Q_length_ratio=0.992 ; DESCRIPTION=Methionine synthase
                     OS=Gloeobacter kilaueensis JS1 GN=metH PE=4 SV=1 ;
                     EVALUE=0.0 ; Q/S_length_ratio=1.007"
                     /note="Pfam_scan:hit_1 (17..322);
                     Pfam:PF02574.11:S-methyl_trans;
                     Pfam_type:Family;HMM_aln_Length:300; HMM_Length:305;
                     EVALUE:3.4e-54; BITSCORE: 184.2"
                     /note="Pfam_scan:hit_2 (351..560);
                     Pfam:PF00809.17:Pterin_bind;
                     Pfam_type:Domain;HMM_aln_Length:208; HMM_Length:210;
                     EVALUE:3e-28; BITSCORE: 98.6"
                     /note="Pfam_scan:hit_3 (648..725);
                     Pfam:PF02607.12:B12-binding_2;
                     Pfam_type:Domain;HMM_aln_Length:76; HMM_Length:79;
                     EVALUE:6.2e-24; BITSCORE: 83.8"
                     /note="Pfam_scan:hit_4 (736..854);
                     Pfam:PF02310.14:B12-binding;
                     Pfam_type:Domain;HMM_aln_Length:117; HMM_Length:121;
                     EVALUE:5.9e-17; BITSCORE: 61.6"
                     /note="Pfam_scan:hit_5 (940..1198);
                     Pfam:PF02965.12:Met_synt_B12;
                     Pfam_type:Domain;HMM_aln_Length:130; HMM_Length:211;
                     EVALUE:1e-21; BITSCORE: 77.1"
                     /note="GO_domain:GO:0006790"
                     /note="GO_domain:GO:0043167"
                     /note="GO_domain:GO:0006520"
                     /note="GO_domain:GO:0008168"
                     /note="GO_domain:GO:0009058"
                     /note="GO_domain:GO:0005622"
                     /note="Enzyme_Code:EC:2.1.1.13"
                     /note="Enzyme_Code:EC:2.1.1"
BEGIN
        1 MPTPLDHPFL NAARERVVIL DGGMGTSLHK YKPTDEDWGH APNGKSLLNL SDALVYTRPE
       61 WIAEIHRGFF ATGCDGVETN TFNANAIGLG EFGMGDKLDE INRLNIRIAK QVAAEFATST
      121 RPRFVIGSIG PGTKMPSLTD PAIYIDFDRL ADAYRPQLRV MIEERVDAIL VETCFDLLQA
      181 KCVAIAAIEE MKRAGVRLPL MVQLTIIDEK KKMLPGTDIP GALVALDPID EIDVVGMNCG
      241 VGPDLMSDDI RHLSRHSRKL LSVLPNAGMP ETRGDETYFP QDPETVAKWL ERFVGEYGAN
      301 IIGGCCGTSH AHLKAVCDKL HGKKPAKRTP VYIPAVSSLQ SAQELLVDQR PLLVGERTNT
      361 NGSKKFKQLL EKDDWHGLVE MAKEQEREGV HVLDVCVDYV GRDGVRDMKE VIKRYNEVLT
      421 KPIMLDSTEV PVIEAGLKLC SGKALINSIN LEDGRKTLDP KTILAKKYGA SLVALTIDEK
      481 GQADTAEWKF EVAKRIYDIV VHEYGIPPTD LMFDTLVFPL STGQEQTRKS AIATFEALRL
      541 IKQNLPGALT HLGLSNCSFG LAPYTRQVLN SMYLHYALEY GLDSAILHAA KIMPLASIDE
      601 TGRELCRRLL FDERVFDAAG NCTEDPLQML IAHYADKKAE SKKSQSLGET VEERLRQAII
      661 QGRRESLVAD LDGARAKHSP IDIINNVLLD GMKVVGELFG SGQMQLPFVL QSAEVMKSAV
      721 AYLEPFMEKV EGAEKGKIVL ATVKGDVHDI GKNLVDIILT NNGYKVYNLG IKQPVDAMIS
      781 AFKEHKADAI GMSGLLVKST VIMKEDLVTL NERGLAPPVI LGGAALNRRY VEHDLRAIYK
      841 GEVFYGADAF EGLHVMDELA RRKKHNVGRA SPALAKLAEG RPGRGIGETG GSTTLEAPPR
      901 ARTTPRAPRA DLPPRSPSLP KAPDVPVPPF IGSRHRTNFD MNEVFKFVNE LTLFSTQWGF
      961 RKGGVDPVVY AKQIEDVAKP ALARLKAQCL AENILRPGVT YGFFPAASDG TKLTIYEADH
     1021 KTPRNTFDFP RQDFGEFLCL SDYVEPLRDG RAVDYVGFTA VTMGREVTRV AQEWYAANRY
     1081 QDYMFLHGLG VESAEALAEY FHQQLRHEWG IGGDDSPVIQ KLFKGHYRGC RYSFGYPACP
     1141 NLEDQKQLFA LIDPTRVGIT LSEQFQLEPE QSTTAIVVHH PDAKYFVTTR TPGCAPTDE
//