LOCUS       EAL49997.1               492 aa    PRT              CON 17-APR-2008
DEFINITION  Entamoeba histolytica HM-1:IMSS Rho guanine nucleotide
            exchange factor, putative protein.
ACCESSION   DS571286-6
PROTEIN_ID  EAL49997.1
SOURCE      Entamoeba histolytica HM-1:IMSS
  ORGANISM  Entamoeba histolytica HM-1:IMSS
            Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida;
            Entamoebidae; Entamoeba.
REFERENCE   1  (bases 1 to 42641)
  AUTHORS   Loftus,B., Anderson,I., Davies,R., Alsmark,U.C., Samuelson,J.,
            Amedeo,P., Roncaglia,P., Berriman,M., Hirt,R.P., Mann,B.J.,
            Nozaki,T., Suh,B., Pop,M., Duchene,M., Ackers,J., Tannich,E.,
            Leippe,M., Hofer,M., Bruchhaus,I., Willhoeft,U., Bhattacharya,A.,
            Chillingworth,T., Churcher,C., Hance,Z., Harris,B., Harris,D.,
            Jagels,K., Moule,S., Mungall,K., Ormond,D., Squares,R.,
            Whitehead,S., Quail,M.A., Rabbinowitsch,E., Norbertczak,H.,
            Price,C., Wang,Z., Guillen,N., Gilchrist,C., Stroup,S.E.,
            Bhattacharya,S., Lohia,A., Foster,P.G., Sicheritz-Ponten,T.,
            Weber,C., Singh,U., Mukherjee,C., El-Sayed,N.M., Petri,W.A. Jr.,
            Clark,C.G., Embley,T.M., Barrell,B., Fraser,C.M. and Hall,N.
  TITLE     The genome of the protist parasite Entamoeba histolytica
  JOURNAL   Nature 433 (7028), 865-868 (2005)
   PUBMED   15729342
REFERENCE   2  (bases 1 to 42641)
  AUTHORS   Lorenzi,H., Amedeo,P., Inman,J., Schobel,S. and Caler,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-MAR-2007) The Institute for Genomic Research, 9712
            Medical Center Drive, Rockville, MD 20850, USA
COMMENT     This version of the project, JCVI-ESG2-1.0, represents 8x coverage
            of the genome.
FEATURES             Qualifiers
     source          /organism="Entamoeba histolytica HM-1:IMSS"
                     /mol_type="genomic DNA"
                     /strain="HM-1:IMSS"
                     /db_xref="taxon:294381"
     protein         /locus_tag="EHI_026350"
                     /old_locus_tag="30.t00048"
                     /note="encoded by transcript EHI_026350A; Contains PF01363
                     : FYVE zinc finger PF00621 : RhoGEF domain PF00169 : PH
                     domain; GO_component: GO:0005622 - intracellular;
                     GO_function: GO:0005089 - Rho guanyl-nucleotide exchange
                     factor activity; GO_function: GO:0008270 - zinc ion
                     binding; GO_process: GO:0035023 - regulation of Rho
                     protein signal transduction"
                     /db_xref="Pathema:EHI_026350"
BEGIN
        1 METISPQSYP SFPRMHEGKC RVKGCNCNRF EGMTDLPDER CSNCFHSIEA HTLPVELFNN
       61 IKCDKPTILT TPREVYRKKI AMELLTTERT YVRMLMTCLR CYADPLQSCE PPLLPPTLYK
      121 SIFLFYRDIV RVNLVFLQSL EDLVEKNQLV SGLSSVFLGT LPYLRVYRMF VGNNSVGLQA
      181 VEQAEHMKDV VKLLHHCSKY GYEGETVQPL RSYLILPIQR IPRYNLLLSD FLKHTDRNDP
      241 LFEETTALVG SLKSLAKEIN DEVKLQDNRR KLLAIKKKFC EGPYHLTLVE AHRYIMREGI
      301 LFKLSKTKPK KRYFYLFNDI LVYGRMQLQL FYPNLYLRLN SVHIEDGLQP NTFNLLSPFK
      361 SFTVICSSIE ERNTWANDLK SAIQKESDKK FSKNIDTVGF DAPLYQPFNE ATLCFICKRK
      421 FGIFCFKYHC ERCGFVVCDS CSKNRKIVPP NPVPQRICNF CVRSADRNIE VFKGLRKRSK
      481 QERARLALAL LE
//