LOCUS       AEC10266.1               561 aa    PRT              PLN 23-MAR-2023
DEFINITION  Arabidopsis thaliana 3-beta hydroxysteroid dehydrogenase/
            isomerase family protein protein.
ACCESSION   CP002685-6668
PROTEIN_ID  AEC10266.1
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 19698289)
  AUTHORS   Lin,X., Kaul,S., Rounsley,S., Shea,T.P., Benito,M.I., Town,C.D.,
            Fujii,C.Y., Mason,T., Bowman,C.L., Barnstead,M., Feldblyum,T.V.,
            Buell,C.R., Ketchum,K.A., Lee,J., Ronning,C.M., Koo,H.L.,
            Moffat,K.S., Cronin,L.A., Shen,M., Pai,G., Van Aken,S., Umayam,L.,
            Tallon,L.J., Gill,J.E., Adams,M.D., Carrera,A.J., Creasy,T.H.,
            Goodman,H.M., Somerville,C.R., Copenhaver,G.P., Preuss,D.,
            Nierman,W.C., White,O., Eisen,J.A., Salzberg,S.L., Fraser,C.M. and
            Venter,J.C.
  TITLE     Sequence and analysis of chromosome 2 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 402 (6763), 761-768 (1999)
   PUBMED   10617197
REFERENCE   2  (bases 1 to 19698289)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
REFERENCE   3  (bases 1 to 19698289)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
FEATURES             Qualifiers
     source          /organism="Arabidopsis thaliana"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:3702"
                     /chromosome="2"
                     /ecotype="Columbia"
     protein         /locus_tag="AT2G43420"
                     /gene_synonym="T1O24.16"
                     /inference="Similar to RNA sequence,
                     EST:INSD:DR366233.1,INSD:AV813487.1,INSD:AU238769.1,
                     INSD:AI996340.1,INSD:BP804906.1,INSD:BP581617.1,
                     INSD:EG439639.1,INSD:ES179685.1,INSD:BP602032.1,
                     INSD:DR366237.1,INSD:EL207376.1,INSD:DR366229.1,
                     INSD:DR366230.1,INSD:BP786318.1,INSD:ES029456.1,
                     INSD:BP603968.1,INSD:DR366235.1,INSD:DR366231.1,
                     INSD:DR366227.1,INSD:ES004966.1,INSD:EL015581.1,
                     INSD:EL116911.1,INSD:ES049908.1,INSD:AV823427.1,
                     INSD:EL181916.1,INSD:AV784387.1,INSD:DR366234.1,
                     INSD:EL286517.1,INSD:BP802360.1,INSD:DR383839.1,
                     INSD:AV797534.1,INSD:BP565651.1,INSD:BP784061.1,
                     INSD:BP588446.1,INSD:EL301580.1,INSD:DR366228.1,
                     INSD:BP575946.1,INSD:EG522845.1,INSD:AV537165.1,
                     INSD:EG439641.1,INSD:AU230007.1,INSD:ES063817.1"
                     /inference="similar to RNA sequence,
                     mRNA:INSD:BX819130.1,INSD:BX818936.1,INSD:AY045841.1,
                     INSD:AK117930.1"
                     /note="3-beta hydroxysteroid dehydrogenase/isomerase
                     family protein; FUNCTIONS IN: binding,
                     3-beta-hydroxy-delta5-steroid dehydrogenase activity,
                     catalytic activity; INVOLVED IN: steroid biosynthetic
                     process, metabolic process; LOCATED IN: plasma membrane;
                     EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15
                     growth stages; CONTAINS InterPro DOMAIN/s: Reticulon
                     (InterPro:IPR003388), 3-beta hydroxysteroid
                     dehydrogenase/isomerase (InterPro:IPR002225),
                     NAD(P)-binding domain (InterPro:IPR016040); BEST
                     Arabidopsis thaliana protein match is:
                     3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2
                     (TAIR:AT2G26260.1); Has 10307 Blast hits to 10296 proteins
                     in 2122 species: Archae - 301; Bacteria - 6803; Metazoa -
                     545; Fungi - 280; Plants - 752; Viruses - 81; Other
                     Eukaryotes - 1545 (source: NCBI BLink)."
                     /db_xref="Araport:AT2G43420"
                     /db_xref="TAIR:AT2G43420"
     intron_pos      83:1 (1/11)
     intron_pos      113:1 (2/11)
     intron_pos      158:0 (3/11)
     intron_pos      215:0 (4/11)
     intron_pos      254:0 (5/11)
     intron_pos      280:2 (6/11)
     intron_pos      345:0 (7/11)
     intron_pos      379:1 (8/11)
     intron_pos      437:2 (9/11)
     intron_pos      490:0 (10/11)
     intron_pos      512:1 (11/11)
BEGIN
        1 MDEDSVHGDS HLKTCVVLGG RGFIGRSLVS RLLRLGNWTV RVADSGHTLH LDESDSLLED
       61 ALSSGRASYH CVDVRDKPQI VKVTEGSYVV FYMGATDLRS HDYFDCYKVI VQGTRNVISA
      121 CRESGVRKLI YNSTADVVFD GSQPIRDGDE SLRRPLKFQS MLTDFKAQAE ALIKLANNRD
      181 GLLTCALRSS IVFGPGDTEF VPFLVNLAKS GYAKFILGSG ENISDFTYSE NVSHAHICAV
      241 KALDSQMEFV AGKEFFITNL KPVRFWDFVS HIVEGLGYPR PSIKLPVRLV LYVFSLLKWT
      301 HEKEGLGSNY DTAHQYALLA SSTRTFNCNA AKKHLGYTPV VTLEDGIAST LQWFSRDLEK
      361 SDDTIIQSTA DQLLGCGKVA DILLWRNEKK TFVSFLVLNL FYYWFFFSGN TFTSSAAQLL
      421 FIFAVALYGV SFVPSKIFGF QVNKIPPWRF EISESAVRDL SSDIVVVWNQ GVRSFKSLSS
      481 GGDWIKFFKI AGSLYLLKLI VSRSLAAFLF TVMSFSFTGF FIYEQYELEL YHLARIFVEC
      541 LTFIKRMVIP VSDASSKPMF M
//