LOCUS       AEC07741.1               367 aa    PRT              PLN 23-MAR-2023
DEFINITION  Arabidopsis thaliana holocarboxylase synthase 1 protein.
ACCESSION   CP002685-3225
PROTEIN_ID  AEC07741.1
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 19698289)
  AUTHORS   Lin,X., Kaul,S., Rounsley,S., Shea,T.P., Benito,M.I., Town,C.D.,
            Fujii,C.Y., Mason,T., Bowman,C.L., Barnstead,M., Feldblyum,T.V.,
            Buell,C.R., Ketchum,K.A., Lee,J., Ronning,C.M., Koo,H.L.,
            Moffat,K.S., Cronin,L.A., Shen,M., Pai,G., Van Aken,S., Umayam,L.,
            Tallon,L.J., Gill,J.E., Adams,M.D., Carrera,A.J., Creasy,T.H.,
            Goodman,H.M., Somerville,C.R., Copenhaver,G.P., Preuss,D.,
            Nierman,W.C., White,O., Eisen,J.A., Salzberg,S.L., Fraser,C.M. and
            Venter,J.C.
  TITLE     Sequence and analysis of chromosome 2 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 402 (6763), 761-768 (1999)
   PUBMED   10617197
REFERENCE   2  (bases 1 to 19698289)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
REFERENCE   3  (bases 1 to 19698289)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
FEATURES             Qualifiers
     source          /organism="Arabidopsis thaliana"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:3702"
                     /chromosome="2"
                     /ecotype="Columbia"
     protein         /gene="HCS1"
                     /locus_tag="AT2G25710"
                     /gene_synonym="F3N11.16"
                     /gene_synonym="F3N11_16"
                     /gene_synonym="HOLOCARBOXYLASE SYNTHASE"
                     /gene_synonym="holocarboxylase synthase 1"
                     /inference="Similar to RNA sequence,
                     EST:INSD:EL069048.1,INSD:EG521966.1,INSD:ES206532.1,
                     INSD:AU239077.1,INSD:AU230349.1,INSD:EH847987.1,
                     INSD:AW004409.1,INSD:EG521965.1,INSD:EL022101.1,
                     INSD:BP651988.1,INSD:BP868188.2,INSD:DR376419.1,
                     INSD:EH886656.1"
                     /inference="similar to RNA sequence, mRNA:INSD:AK118225.1"
                     /note="holocarboxylase synthase 1 (HCS1); FUNCTIONS IN:
                     biotin-[acetyl-CoA-carboxylase] ligase activity, catalytic
                     activity; INVOLVED IN: protein modification process;
                     EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13
                     growth stages; CONTAINS InterPro DOMAIN/s: Biotin protein
                     ligase, C-terminal (InterPro:IPR003142), Biotin/lipoate
                     A/B protein ligase (InterPro:IPR004143),
                     Biotin--acetyl-CoA-carboxylase ligase
                     (InterPro:IPR004408); BEST Arabidopsis thaliana protein
                     match is: holocarboxylase synthetase 2 (TAIR:AT1G37150.2);
                     Has 6039 Blast hits to 6035 proteins in 2305 species:
                     Archae - 225; Bacteria - 4034; Metazoa - 119; Fungi - 135;
                     Plants - 62; Viruses - 0; Other Eukaryotes - 1464 (source:
                     NCBI BLink)."
                     /db_xref="Araport:AT2G25710"
                     /db_xref="TAIR:AT2G25710"
     intron_pos      38:1 (1/9)
     intron_pos      129:2 (2/9)
     intron_pos      150:1 (3/9)
     intron_pos      200:0 (4/9)
     intron_pos      240:1 (5/9)
     intron_pos      292:1 (6/9)
     intron_pos      307:2 (7/9)
     intron_pos      330:0 (8/9)
     intron_pos      355:2 (9/9)
BEGIN
        1 MEAVRSTTTL SNFHLLNILV LRSLKPLHRL SFSFSASAME SDASCSLVLC GKSSVETEVA
       61 KGLKNKNSLK LPDNTKVSLI LESEAKNLVK DDDNSFNLSL FMNSIITHRF GRFLIWSPRL
      121 SSTHDVVSHN FSELPVGSVC VTDIQFKGRG RTKNVWESPK GCLMYSFTLE MEDGRVVPLI
      181 QYVVSLAVTE AVKDVCDKKG LPYIDVKIKW PNDLYVNGLK VGGILCTSTY RSKKFNVSVG
      241 VGLNVDNGQP TTCLNAVLKG MAPESNLLKR EEILGAFFHK FEKFFDLFMD QGFKSLEELY
      301 YRTWLHSEQR VIVEDKVEDQ VVQNVVTIQG LTSSGYLLAV GDDNQMYELH PDGNSFDFFK
      361 GLVRRKI
//