LOCUS       AEC06489.1               519 aa    PRT              PLN 23-MAR-2023
DEFINITION  Arabidopsis thaliana thymidylate synthase 1 protein.
ACCESSION   CP002685-1490
PROTEIN_ID  AEC06489.1
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 19698289)
  AUTHORS   Lin,X., Kaul,S., Rounsley,S., Shea,T.P., Benito,M.I., Town,C.D.,
            Fujii,C.Y., Mason,T., Bowman,C.L., Barnstead,M., Feldblyum,T.V.,
            Buell,C.R., Ketchum,K.A., Lee,J., Ronning,C.M., Koo,H.L.,
            Moffat,K.S., Cronin,L.A., Shen,M., Pai,G., Van Aken,S., Umayam,L.,
            Tallon,L.J., Gill,J.E., Adams,M.D., Carrera,A.J., Creasy,T.H.,
            Goodman,H.M., Somerville,C.R., Copenhaver,G.P., Preuss,D.,
            Nierman,W.C., White,O., Eisen,J.A., Salzberg,S.L., Fraser,C.M. and
            Venter,J.C.
  TITLE     Sequence and analysis of chromosome 2 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 402 (6763), 761-768 (1999)
   PUBMED   10617197
REFERENCE   2  (bases 1 to 19698289)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
REFERENCE   3  (bases 1 to 19698289)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
FEATURES             Qualifiers
     source          /organism="Arabidopsis thaliana"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:3702"
                     /chromosome="2"
                     /ecotype="Columbia"
     protein         /gene="THY-1"
                     /locus_tag="AT2G16370"
                     /gene_synonym="DIHYDROFOLATE REDUCTASE-THYMIDYLATE
                     SYNTHASE"
                     /gene_synonym="F16F14.13"
                     /gene_synonym="F16F14_13"
                     /gene_synonym="thymidylate synthase 1"
                     /inference="Similar to RNA sequence,
                     EST:INSD:BP633601.1,INSD:BX840101.1,INSD:ES175805.1,
                     INSD:BP665940.1,INSD:EH878023.1,INSD:AV785857.1,
                     INSD:BP846629.1,INSD:EL229296.1,INSD:AV824362.1,
                     INSD:BP573673.1,INSD:BP626187.1,INSD:EL066321.1,
                     INSD:ES129490.1,INSD:ES071234.1,INSD:BX836058.1,
                     INSD:EL339429.1,INSD:BP580480.1"
                     /inference="similar to RNA sequence,
                     mRNA:INSD:AY114032.1,INSD:AY063968.1"
                     /note="thymidylate synthase 1 (THY-1); CONTAINS InterPro
                     DOMAIN/s: Thymidylate synthase, active site
                     (InterPro:IPR020940), Dihydrofolate reductase domain
                     (InterPro:IPR001796), Dihydrofolate reductase conserved
                     site (InterPro:IPR017925), Bifunctional dihydrofolate
                     reductase/thymidylate synthase (InterPro:IPR012262),
                     Thymidylate synthase (InterPro:IPR000398); BEST
                     Arabidopsis thaliana protein match is: thymidylate
                     synthase 2 (TAIR:AT4G34570.1); Has 13474 Blast hits to
                     13433 proteins in 2607 species: Archae - 76; Bacteria -
                     8708; Metazoa - 513; Fungi - 424; Plants - 92; Viruses -
                     253; Other Eukaryotes - 3408 (source: NCBI BLink)."
                     /db_xref="Araport:AT2G16370"
                     /db_xref="TAIR:AT2G16370"
     intron_pos      141:2 (1/8)
     intron_pos      269:0 (2/8)
     intron_pos      284:0 (3/8)
     intron_pos      306:0 (4/8)
     intron_pos      326:2 (5/8)
     intron_pos      351:2 (6/8)
     intron_pos      407:0 (7/8)
     intron_pos      484:0 (8/8)
BEGIN
        1 MATTTLNDSV TTTLASEPQR TYQVVVAATK EMGIGKDGKL PWNLPTDLKF FKDITLTTSD
       61 SSKKNAVVMG RKTWESIPIK YRPLSGRLNV VLTRSGGFDI ANTENVVTCS SVDSALDLLA
      121 APPYCLSIER VFVIGGGDIL REALNRPSCD AIHLTEIDTS VDCDTFIPAI DTSVYQPWSS
      181 SFPVTENGLR FCFTTFVRVK SSADESSDES NGSQSLQFDG KKFLFLPKMV FDQHEEFLYL
      241 NMVEDIISNG NVKNDRTGTG TLSKFGCQMK FNLRRSFPLL TTKRVFWRGV VEELLWFISG
      301 STNAKVLQEK GIHIWDGNAS REYLDGIGLT EREEGDLGPV YGFQWRHFGA KYTDMHADYT
      361 GQGFDQLVDV IDKIKNNPDD RRIIMSAWNP SDLKLMALPP CHMFAQFYVA EGELSCQMYQ
      421 RSADMGLGVP FNIASYSLLT CMLAHVCDLV PGDFIHVLGD AHVYKTHVRP LQEQLLNLPK
      481 PFPVMKINPE KKQIDSFVAS DFDLTGYDPH KKIEMKMAV
//