LOCUS AAH57394.1 1562 aa PRT HUM 24-JUL-2018 DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 11 protein. ACCESSION BC057394-1 PROTEIN_ID AAH57394.1 SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 6904) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 6904) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (03-SEP-2003) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov REFERENCE 3 (bases 1 to 6904) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (24-JUL-2018) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK Sequence update by database staff to remove vector contamination COMMENT On Jul 24, 2018 this sequence version replaced BC057394.1. Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: ATCC/DCTD/DTP cDNA Library Preparation: Life Technologies, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Sequencing Group at the Stanford Human Genome Center, Stanford University School of Medicine, Stanford, CA 94305 Web site: http://www-shgc.stanford.edu Contact: (Dickson, Mark) mcd@paxil.stanford.edu Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers, R. M. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAK Plate: 110 Row: k Column: 9 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 38026933. FEATURES Qualifiers source /db_xref="H-InvDB:HIT000259693" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:60344 IMAGE:6148684" /tissue_type="Skin, melanotic melanoma." /clone_lib="NIH_MGC_72" /lab_host="DH10B" /note="Vector: pCMV-SPORT6" protein /gene="ARHGEF11" /gene_synonym="GTRAP48" /gene_synonym="KIAA0380" /gene_synonym="PDZ-RHOGEF" /db_xref="GeneID:9826" /db_xref="HGNC:HGNC:14580" /db_xref="MIM:605708" BEGIN 1 MSVRLPQSID RLSSLSSLGD SAPERKSPSH HRQPSDASET TGLVQRCVII QKDQHGFGFT 61 VSGDRIVLVQ SVRPGGAAMK AGVKEGDRII KVNGTMVTNS SHLEVVKLIK SGAYVALTLL 121 GSSPSSMGIS GLQQDPSPAG APRITSVIPS PPPPPPLPPP QRITGPKPLQ DPEVQKHATQ 181 ILRNMLRQEE KELQRICEVY SRNPASLLEE QIEGARRRVT QLQLKIQQET GGSVDILPLY 241 GDTSQRPSEG RLSLDSQEGD SGLDSGTERF PSLSESLMNR NSVLSDPGLD SPRTSPVIMA 301 RVAQHHRRQG SDAAVPSTGD QGVDQSPKPL IIGPEEDYDP GYFNNESDII FQDLEKLKSR 361 PAHLGVFLRY IFSQADPSPL LFYLCAEVYQ QASPKDSRSL GKDIWNIFLE KNAPLRVKIP 421 EMLQAEIDSR LRNSEDARGV LCEAQEAAMP EIQEQIHDYR TKRTLGLGSL YGENDLLDLD 481 GDPLRERQVA EKQLAALGDI LSKYEEDRSA PMDFALNTYM SHAGIRLREA RPSNTAEKAQ 541 SAPDKDKWLP FFPKTKKSSN SKKEKDALED KKRNPILKYI GKPKSSSQST FHIPLSPVEV 601 KPGNVRNIIQ HFENNQQYDA PEPGTQRLST GSFPEDLLES DSSRSEIRLG RSESLKGREE 661 MKRSRKAENV PRSRSDVDMD AAAEATRLHQ SASSSTSSLS TRSLENPTPP FTPKMGRRSI 721 ESPSLGFCTD TLLPHLLEDD LGQLSDLEPE PDAQNWQHTV GKDVVAGLTQ REIDRQEVIN 781 ELFVTEASHL RTLRVLDLIF YQRMKKENLM PREELARLFP NLPELIEIHN SWCEAMKKLR 841 EEGPIIKEIS DLMLARFDGP AREELQQVAA QFCSYQSIAL ELIKTKQRKE SRFQLFMQEA 901 ESHPQCRRLQ LRDLIISEMQ RLTKYPLLLE SIIKHTEGGT SEHEKLCRAR DQCREILKYV 961 NEAVKQTENR HRLEGYQKRL DATALERASN PLAAEFKSLD LTTRKMIHEG PLTWRISKDK 1021 TLDLHVLLLE DLLVLLQKQD EKLLLKCHSK TAVGSSDSKQ TFSPVLKLNA VLIRSVATDK 1081 RAFFIICTSK LGPPQIYELV ALTSSDKNTW MELLEEAVRN ATRHPGAAPM PVHPPPPGPR 1141 EPAQQGPTPS RVELDDSDVF HGEPEPEELP GGTGSQQRVQ GKHQVLLEDP EQEGSAEEEE 1201 LGVLPCPSTS LDGENRGIRT RNPIHLAFPG PLFMEGLADS ALEDVENLRH LILWSLLPGH 1261 TMETQAAQEP EDDLTPTPSV ISVTSHPWDP GSPGQAPPGG EGDNTQLAGL EGERPEQEDM 1321 GLCSLEHLPP RTRNSGIWES PELDRNLAED ASSTEAAGGY KVVRKAEVAG SKVVPALPES 1381 GQSEPGPPEV EGGTKATGNC FYVSMPSGPP DSSTDHSEAP MSPPQPDSLP AGQTEPQPQL 1441 QGGNDDPRRP SRSPPSLALR DVGMIFHTIE QLTLKLNRLK DMELAHRELL KSLGGESSGG 1501 TTPVGSFHTE AARWTDGSLS PPAKEPLASD SRNSHELGPC PEDGSDAPLE DSTADAAASP 1561 GP //