ID P84479_MELGA Unreviewed; 146 AA.
AC P84479;
DT 29-MAR-2005, integrated into UniProtKB/TrEMBL.
DT 29-MAR-2005, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Hemoglobin beta chain {ECO:0000313|PIR:S56104};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103;
RN [1] {ECO:0007829|PDB:3K8B}
RP X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH HEME B.
RA Ramesh P., Sundaresan S.S., Ponnuswamy M.N.;
RT "Crystal structure of Turkey (Meleagiris gallopova)hemoglobin at 2.3
RT Angstrom.";
RL Submitted (OCT-2009) to the PDB data bank.
RN [2] {ECO:0007829|PDB:6ZMX}
RP X-RAY CRYSTALLOGRAPHY (1.39 ANGSTROMS) IN COMPLEX WITH HEME B.
RX PubMed=33950023; DOI=10.1107/s2059798321003417;
RA Ramesh P., Sundaresan S.S., Shobana N., Vinuchakkaravarthy T.,
RA Sivakumar K., Yasien S., Ponnuswamy M.N.G.;
RT "Structural studies of hemoglobin from two flightless birds, ostrich and
RT turkey: insights into their differing oxygen-binding properties.";
RL Acta Crystallogr. D Struct. Biol. 77:690-702(2021).
CC -!- SIMILARITY: Belongs to the globin family.
CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC ECO:0000256|RuleBase:RU000356}.
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DR PIR; S56104; S56104.
DR PDB; 3K8B; X-ray; 2.30 A; B/D=1-146.
DR PDB; 6ZMX; X-ray; 1.39 A; B/D=1-146.
DR PDBsum; 3K8B; -.
DR AlphaFoldDB; P84479; -.
DR SMR; P84479; -.
DR HOGENOM; CLU_003827_10_0_1; -.
DR OMA; FRLLCEC; -.
DR EvolutionaryTrace; P84479; -.
DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd08925; Hb-beta-like; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR002337; Hemoglobin_b.
DR PANTHER; PTHR11442; HEMOGLOBIN FAMILY MEMBER; 1.
DR PANTHER; PTHR11442:SF7; HEMOGLOBIN SUBUNIT EPSILON; 1.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00814; BETAHAEM.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3K8B, ECO:0007829|PDB:6ZMX};
KW Heme {ECO:0000256|RuleBase:RU000356, ECO:0007829|PDB:3K8B};
KW Iron {ECO:0007829|PDB:3K8B, ECO:0007829|PDB:6ZMX};
KW Metal-binding {ECO:0007829|PDB:3K8B, ECO:0007829|PDB:6ZMX};
KW Oxygen transport {ECO:0000256|ARBA:ARBA00022621,
KW ECO:0000256|RuleBase:RU000356}; Transport {ECO:0000256|RuleBase:RU000356}.
FT DOMAIN 4..146
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
FT BINDING 66
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:6ZMX"
FT BINDING 92
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_label="1"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /ligand_part_note="axial binding residue"
FT /evidence="ECO:0007829|PDB:3K8B"
FT BINDING 92
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_label="2"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /ligand_part_note="axial binding residue"
FT /evidence="ECO:0007829|PDB:6ZMX"
SQ SEQUENCE 146 AA; 16307 MW; CE323CA9BBE08B28 CRC64;
VHWSAEEKQL ITGLWGKVNV ADCGAEALAR LLIVYPWTQR FFASFGNLSS PTAILGNPMV
RAHGKKVLTS FGDAVKNLDN IKNTFSQLSE LHCDKLHVDP ENFRLLGDIL IIVLAAHFSK
DFTPECQAAW QKLVRVVAHA LARKYH
//