LOCUS BC066889 1131 bp mRNA linear HUM 16-DEC-2006
DEFINITION Homo sapiens high-mobility group box 1, mRNA (cDNA clone MGC:86954
IMAGE:5268698), complete cds.
ACCESSION BC066889
VERSION BC066889.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1131)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1131)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: m Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56806672.
FEATURES Location/Qualifiers
source 1..1131
/db_xref="H-InvDB:HIT000262310"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:86954 IMAGE:5268698"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..1131
/gene="HMGB1"
/gene_synonym="HMG3"
/gene_synonym="SBP-1"
/db_xref="GeneID:3146"
/db_xref="HGNC:HGNC:4983"
/db_xref="MIM:163905"
CDS 80..727
/gene="HMGB1"
/gene_synonym="HMG3"
/gene_synonym="SBP-1"
/codon_start=1
/product="high-mobility group box 1"
/protein_id="AAH66889.1"
/db_xref="GeneID:3146"
/db_xref="HGNC:HGNC:4983"
/db_xref="MIM:163905"
/translation="MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKK
CSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAF
FLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA
AYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE"
BASE COUNT 386 a 188 c 283 g 274 t
ORIGIN
1 atagagacag cgccggggca agtgagagcc ggacgggcac tgggcgactc tgtgcctcgc
61 tgaggaaaaa taactaaaca tgggcaaagg agatcctaag aagccgagag gcaaaatgtc
121 atcatatgca ttttttgtgc aaacttgtcg ggaggagcat aagaagaagc acccagatgc
181 ttcagtcaac ttctcagagt tttctaagaa gtgctcagag aggtggaaga ccatgtctgc
241 taaagagaaa ggaaaatttg aagatatggc aaaagcggac aaggcccgtt atgaaagaga
301 aatgaaaacc tatatccctc ccaaagggga gacaaaaaag aagttcaagg atcccaatgc
361 acccaagagg cctccttcgg ccttcttcct cttctgctct gagtatcgcc caaaaatcaa
421 aggagaacat cctggcctgt ccattggtga tgttgcgaag aaactgggag agatgtggaa
481 taacactgct gcagatgaca agcagcctta tgaaaagaag gctgcgaagc tgaaggaaaa
541 atacgaaaag gatattgctg catatcgagc taaaggaaag cctgatgcag caaaaaaggg
601 agttgtcaag gctgaaaaaa gcaagaaaaa gaaggaagag gaggaagatg aggaagatga
661 agaggatgag gaggaggagg aagatgaaga agatgaagat gaagaagaag atgatgatga
721 tgaataagtt ggttctagcg cagttttttt tttcttgtct ataaagcatt taacccccct
781 gtacacaact cactcctttt aaagaaaaaa attgaaatgt aaggctgtgt aagatttgtt
841 tttaaactgt acagtgtctt tttttgtata gttaacacac taccgaatgt gtctttagat
901 agccctgtcc tggtggtatt ttcaatagcc actaaccttg cctggtacag tatgggggtt
961 gtaaattggc atggaaattt aaagcaggtt cttgttggtg cacagcacaa attagttata
1021 tatggggatg gtagtttttt catcttcagt tgtctctgat gcagcttata cgaaataatt
1081 gttgttctgt taactgaata ccactctgta attgcaaaaa aaaaaaaaaa a
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