LOCUS BC060790 4128 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens suppressor of cytokine signaling 4, mRNA (cDNA clone
MGC:71581 IMAGE:30338646), complete cds.
ACCESSION BC060790
VERSION BC060790.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4128)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4128)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 133 Row: d Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40807479.
FEATURES Location/Qualifiers
source 1..4128
/db_xref="H-InvDB:HIT000260092"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71581 IMAGE:30338646"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4128
/gene="SOCS4"
/db_xref="GeneID:122809"
/db_xref="HGNC:HGNC:19392"
CDS 444..1766
/gene="SOCS4"
/codon_start=1
/product="suppressor of cytokine signaling 4"
/protein_id="AAH60790.1"
/db_xref="GeneID:122809"
/db_xref="HGNC:HGNC:19392"
/translation="MAENNENISKNVDVRPKTSRSRSADRKDGYVWSGKKLSWSKKSE
SYSDAETVNGIEKTEVSLRNQERKHSCSSIELDLDHSCGHRFLGRSLKQKLQDAVGQC
FPIKNCSSRHSSGLPSKRKIHISELMLDKCPFPPRSDLAFRWHFIKRHTAPINSKSDE
WVSTDLSQTELRDGQLKRRNMEENINCFSHTNVQPCVITTDNALCREGPMTGSVMNLV
SNNSIEDSDMDSDDEILTLCTSSRKRNKPKWDLDDEILQLETPPKYHTQIDYVHCLVP
DLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHAR
IEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFSLQHI
CRTVICNCTTYDGIDALPIPSSMKLYLKEYHYKSKVRVLRIDAPEQQC"
BASE COUNT 1307 a 722 c 752 g 1347 t
ORIGIN
1 gcggcgccca gggaaccggc ggaggcgatg accgtgacgg ctgggttggg accggaacgc
61 cgaagcgggg ttgggggtgg cagaaaagca tctgctttgt aagacctaca cgaggtgcag
121 gagtggttgg gcctcccctc tccacttaag caagcgccca gactgatggc gatggtgatg
181 gcagcagtta ctcgcacaac cccagttaag ctgcgctccg ggaggagttc atctgttgtc
241 tgctctccag tgacttccgt ttgtggagcc taagtgtttc tacagaatcc aactcaaata
301 tcaaggacta tgatcagaat gctttcaagg agtttttggg cacatgatgg cagatacatc
361 cagaaagtgc ccagaagaaa cttcctgctg gaaaaaatga aaaagcagta tttataacat
421 tagaatctgg ataatttgtt aacatggcag aaaataatga aaatattagt aaaaatgtag
481 atgtaaggcc caaaactagt cggagcagaa gtgccgacag aaaagacggt tatgtgtgga
541 gtggaaagaa gttatcttgg tcaaaaaaga gtgagagtta ttcagatgct gagacagtga
601 atggtataga gaaaaccgaa gtgtctttaa ggaaccaaga aaggaagcac agctgttcat
661 ccattgagtt ggacttagat cattcctgtg ggcatcgatt tttaggccga tctcttaaac
721 agaaactgca agatgccgtg gggcagtgtt ttccaataaa gaattgtagt agtcggcact
781 cttcagggct tccgtctaaa aggaaaattc atatcagtga actcatgtta gataagtgtc
841 ctttcccacc tcgatcagat ttagccttta ggtggcattt tattaaacga cacactgctc
901 ctataaattc caaatcagat gaatgggtaa gcacagactt gtctcagact gaattgaggg
961 atggtcagct aaaacgaaga aatatggaag aaaatataaa ctgtttctca cataccaatg
1021 ttcagccctg tgtcataacc accgacaatg ctttgtgtag agaaggtcct atgactggct
1081 ctgtgatgaa cctggtttca aataacagta tagaagatag tgatatggat tccgatgatg
1141 aaattctaac actttgcaca agttccagaa aaagaaacaa acccaaatgg gatttggatg
1201 atgaaatcct gcagttggaa acacctccta aataccacac gcagattgat tatgtccact
1261 gtcttgtacc agacctcctt cagatcaata acaacccatg ttactgggga gtgatggata
1321 aatacgcagc cgaagcacta ctggaaggaa aaccagaggg taccttttta cttcgagact
1381 cagcacagga agactattta ttctctgtta gttttagacg ctatagtcgt tctcttcatg
1441 ctagaattga acagtggaat cacaacttta gctttgatgc acatgacccc tgtgtcttcc
1501 attctcctga cattactggg ctcctagaac attataagga cccaagcgcc tgtatgttct
1561 ttgaaccact tctatccact cccttaattc ggactttccc tttttccctg cagcatatat
1621 gcagaacagt tatttgtaac tgtacaactt atgatggcat cgatgccctt ccaattcctt
1681 cttctatgaa attatatctg aaggaatatc attataaatc aaaagttaga gtactcagga
1741 ttgatgcacc agaacagcaa tgctagtaac aggatgggaa catgggaatg ataatatata
1801 ttttttcttt taatatttta tttttctttt tatgccactt tggatttttc tacaaaggca
1861 gtggtgtcca aaataaaatc tctgccctaa attttactaa taaatccatt tttctagtga
1921 tacacaaatt gtttaaggtt atacactcga gcttaaatag atatttttaa ccaggtgttt
1981 ggtttttgtt tttaccgtgt aggttgtata cttacatttt ttctttcctt aatttataca
2041 tgatcctttt tccttaattt atacatgatc caggcacatt tgaaatttgg taggcattgc
2101 aaacacattt gaatattgtg tatttcatac tattctttaa aagtaatctt atgtcctttc
2161 ctacatgtaa aatattttgt taatctatgc cattagtagt attatatata aaatatagtt
2221 ccccgtcccc cttttcattg agtttgatat tcttcagtaa agctgaatgt tgtaattcac
2281 cattcatact aatgttattg acttttgtaa cttactaata gggatgttaa aagtaacaaa
2341 accaagtcaa acttggtgta tttttatttt aaatattaac tctaaagcag gattactaaa
2401 tttgattaat ctggtcaatg agaatcaaat ggaaacatat cattctggag gtgcacttac
2461 tcttctacaa tgtggccgga tcatttgtca ttcctgaata ggtctttctc tcaacctgca
2521 agagctaaac catcttcaaa acataaatct tgttcctttc tcattggaag ctttgaaaat
2581 aatgataaca ctattagtag ctagtagtta ctaaagtgct aaagtaattg tggggttttt
2641 ctgtattagc ttatgaactg ttgcttctac ttagcccttt tatagaaact ctgagctgtt
2701 actttgggga aattccacaa tgtattagca gccacaaatt tccactggta accaaagagt
2761 acctaagtag tttttcatta ttttaagttg aatttgaata aagattccag aaataaacat
2821 ggagctcagt attcaggaag cttaatactg tttttgatct acaagatcca aataattatc
2881 cctatcttca gaattaactt agtctgtaat gtggcttcaa aaaaagaaag ccttttgaca
2941 gctacatgac ttacaccata cagaacagta ctggacaaaa ggggtgatat tttaaattta
3001 ctatcccaga aacagggcaa cgtttttaga aacatcttta gcccaaagta actagtaaaa
3061 ataaatggag tggtatccta tcttcttttt ttaaggaatc aatgaataat aaatgtagat
3121 agacaatttt cttctggtga gctgtctaac cctttgtaca cattgacatt tttaatatcg
3181 taactgattt cttgatgcta gtttagctat attaggaaac tgcttctacc tagattgaaa
3241 gaaatttgac tcataaactt ccaagttaga acaaatattt cttcattatt gttgctttta
3301 tgtgagtagc atttccctat cttgcagttc tgttaacatg aaaatggcat ttttccataa
3361 tagctttaaa ataatttttt agtaattatt acaaaattaa ggaaaatctc tattaccgtt
3421 atcttttagc attttttttt tcctcagtga tctcaagatt gtcttagtct caatgagatg
3481 tagctacaaa aatggcacct cttagcagtg atgaggctca ggatatcgga tatcataaca
3541 ccaatgtcag gataaatatc tcttctaaag acgatattta ccttttacaa ggttagaaaa
3601 gtctcatact acctcatctt tattgtggcg cttttgtaga tcactgagaa gcttatctta
3661 ttaaccaata taccacttcc taaatatcca tctttggtga aagaaaatag tgtggtaaga
3721 gtacccatga ttatagtttt ttatcagaat ttgataagat tttctgtttc tgtgaaacaa
3781 ttattttaaa tatttttctt ttaaaaataa ctttttatca gtacagaaaa acctaaggga
3841 tgactagctt acaaatattc tgttaagggg tagttttata aagaaaaatg atatatagtt
3901 atgttgtctt ttatagtgtt aaaattagta tttatatgaa agtcaagatc taagtacctt
3961 ttcatataat tcaaactgat tgcttgtgat atgttttctc tggctttttt attttttcaa
4021 cttcaaggta ttaacagctg ttaacactta aaaagtactg ccacatatgt agccttgaag
4081 tagttgatct aataaatgag agcagggagg agaaaaaaaa aaaaaaaa
//