LOCUS BC040187 4823 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens HECT domain containing 2, mRNA (cDNA clone MGC:42202
IMAGE:4811444), complete cds.
ACCESSION BC040187
VERSION BC040187.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4823)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4823)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-NOV-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 70 Row: k Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27735098.
FEATURES Location/Qualifiers
source 1..4823
/db_xref="H-InvDB:HIT000096052"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:42202 IMAGE:4811444"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4823
/gene="HECTD2"
/db_xref="GeneID:143279"
/db_xref="HGNC:HGNC:26736"
CDS 98..2428
/gene="HECTD2"
/codon_start=1
/product="HECT domain containing 2"
/protein_id="AAH40187.1"
/db_xref="GeneID:143279"
/db_xref="HGNC:HGNC:26736"
/translation="MSEAVRVPSPATPLVVAAAAPEERKGKESEREKLPPIVSAGAGA
TAGLDRGAKGQISTFSSFISAVSPKKEAAENRSSPAHLVFLNIKNVREPPPICLDVRQ
KQRTSMDASSSEMKAPVLPEPILPIQPKTVKDFQEDVEKVKSSGDWKAVHDFYLTTFD
SFPELNAAFKKDATASFNTIEDSGINAKFVNAVYDTLLNTPQDVQKTVLKGIINSLLR
EWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQIATLVEADHHFLVHWFKKLS
QKRFKQLVERLLQFISLRLFPAKPEEFPPITKCSWWIPSAAKVLALLNTANNLVHPPL
IPYTDFYNSTLDHIDLMEEYHTWQNFGNSHRFSFCQYPFVISVAAKKIIIQRDSEQQM
INIARQSLVDKVSRRQRPDMNILFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFV
GEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGIL
MGLAVYNSITFDIRFPPCCYKKLLSPPIIPSGQNIPVGICNVTVDDLCQIMPELAHGL
SELLSHEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTDFL
LNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPDLDMHALQRSTQYDGYA
KTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNCLPV
AHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE"
BASE COUNT 1527 a 887 c 871 g 1538 t
ORIGIN
1 agcgagtcct ctcgcggccg cggcggcagc agcagcgcca gccccagcaa cactgaggcc
61 gccgccgccg cctggcgctc ccgccgcccg gcccgacatg agtgaggcgg ttcgggtacc
121 ctcgcccgcc actccgctgg tggtggcggc ggccgcgcct gaggagagga aagggaagga
181 gtcagagcgc gagaagctgc cgcccatcgt atcggcgggc gccggcgcga ccgcgggttt
241 ggacagagga gccaaaggcc aaatttccac tttcagcagt tttatttcag ctgttagccc
301 gaagaaagaa gctgctgaaa acagaagttc acctgcacat cttgttttcc ttaacatcaa
361 gaatgtgaga gaaccaccac caatttgcct tgatgttaga caaaaacagc gtacatctat
421 ggatgcatca tcatccgaaa tgaaggcccc agtccttcca gaacctattc ttcctatcca
481 gcccaaaact gtgaaagact ttcaggaaga tgtagaaaaa gttaagtcat caggagattg
541 gaaagcagta catgattttt atctaacaac gtttgattct ttcccagaat taaatgctgc
601 atttaagaaa gatgccactg cctcatttaa caccattgaa gactctggga ttaatgctaa
661 atttgtgaat gctgtgtatg ataccttact taatactcct caagacgttc agaagacagt
721 attaaaggga atcattaaca gcctgttacg agaatggaaa ggtccacgaa caaaagatga
781 tcttagagca tattttatac ttttacagaa tcctcagttt aataacacat ctacgtatgt
841 catctatgct cacttgctac gacagatagc taccttagtg gaagctgacc atcatttcct
901 agttcactgg tttaaaaaat tgtcccagaa gaggttcaaa caattggtag agagattgct
961 gcaatttatt tctttacgcc tgtttcctgc aaagcctgaa gaatttccac ctataacaaa
1021 gtgttcctgg tggattccat cagccgctaa agtgttggct ttacttaata ctgcaaacaa
1081 tttagttcac cctcccctta ttccttatac tgatttctat aattctacat tggatcacat
1141 tgatctcatg gaagaatatc atacttggca aaactttgga aactctcaca ggttttcctt
1201 ctgtcagtac ccattcgtta tttctgtagc tgcaaaaaaa atcattattc agagagactc
1261 agagcaacag atgataaaca tcgcaaggca aagtctggtg gataaagtat ctcgaagaca
1321 gagacctgat atgaatatat tatttctaaa tatgaaagta agacggacac atctggttag
1381 cgattcactt gatgagctaa cccggaaaag agccgatttg aaaaagaagt taaaagttac
1441 atttgtaggg gaagctggtt tggatatggg tggtttgact aaagaatggt tccttcttct
1501 aattcgccaa atttttcatc cagattatgg catgtttaca tatcacaagg attcacactg
1561 ccattggttt agcagcttta aatgtgataa ctattctgaa ttccgattgg ttggaattct
1621 tatgggacta gctgtttata acagcatcac cttcgatatt cgtttccctc cctgctgtta
1681 caagaaatta ttgagccctc ccatcattcc tagtggtcaa aatataccag taggcatctg
1741 caatgttacc gtggacgact tatgtcaaat tatgcctgag ttggcccatg gattaagtga
1801 actcttatca catgaaggca atgttgaaga agatttctat tcaacatttc aggtttttca
1861 agaagaattt ggaataatca agtcctataa tttaaagccc ggtggtgata aaatttcagt
1921 taccaatcaa aatagaaaag aatatgtaca gctttatact gacttccttc tgaacaaatc
1981 catctataag cagtttgctg cattttatta tggatttcat agtgtgtgtg cttcaaatgc
2041 cctaatgctg cttcgtccag aagaggttga aattttggtc tgtggaagtc ctgacctgga
2101 tatgcatgct ctgcagagaa gtactcagta tgatggctat gcaaaaacgg acttaactat
2161 aaaatacttt tgggatgttg tgcttggatt tcctcttgat cttcaaaaga agttgctaca
2221 ttttactaca gggagtgaca gagtacctgt aggagggatg gctgatttga actttaaaat
2281 ctcaaagaat gaaacttcta ctaactgctt acctgtggcc catacctgct tcaatcaact
2341 ttgccttccc ccctacaaga gcaaaaagga tctgaaacag aaattgatca ttggaatttc
2401 aaattcagaa ggttttggac ttgagtaacc tagaagactt gaaatataat cttttatatg
2461 tagcattcac ttccctctta ctgtgccttt agccttttca tgtttctgtc tcaaaacact
2521 ttgacaaagc tcaccaactt taaaatatta agtttttaaa aaatcaaata tgaagtatgt
2581 tcagcaaagg cataattttc taaaaacaca cacagaaatc gcttgagtga ggaaaagtcc
2641 acatggcaga gacaggtatg gtccagttcc tcttttatat agcactttat cattctccac
2701 aagtagtttg tcacaggcat tccactggga aagcaaagta cagtgaagaa tgaatttatg
2761 gtatagttga acccagtggc agattgtaca ctgctagcac tgctagcaca cagtagcaaa
2821 gcaaacagct acattatctt taacataagg catgtagcca tattttcata tagtggtata
2881 caacacagta tcattgcaaa tgcagtttac agggattttt gatatactgg cttgggacct
2941 ataagattct tctcagcagt tgctgaaaag catgtaaata actacataat agcctgagaa
3001 taatgggatt ttgatagtgc catttattgt taaagattta tttttacaaa gtaaattcag
3061 ggttttagat gtgtacacag cttttacaaa tcaataaaga tgattgtaca agagtatttt
3121 cagactaatt ggattcaagg ttatattctt ttaagtgttg ttagtctgca tgcacattgg
3181 cagtaaacta gttacttgtg tactctgtaa tatttgtata atgatcattt cttcttaagg
3241 ctcaagatat tagaaaagaa atcagaccta aataatcatt gatgaagtat gtcagttaca
3301 agcacaaaag aatataactg cttttataaa tcttttgaat catgtacaag acttatatct
3361 acattttttg atcaccagtt gtaccaaaac actaattttt gaaaaagata ggttaaagta
3421 tttgacaaaa gtgaatacaa taataacact tgtgtcaaaa tgatatagct tagtataaaa
3481 ataaaattca acgttttggc caaaatgttt gtttttcact ggattctgaa tataataaat
3541 tcaaagtacc ctttttttag agtttctaat aaagtagtat gtaaaaagaa actgcatttt
3601 aagtcagaca gtaaatgttt tttttaattt acagcaaatg aagcagtttt attagcatgt
3661 tacaaatatt gccaaaccaa gacttctcta ccatacttta acagctttcc ttcagaaaac
3721 tctgaagtta tatttgcaat aataatgaaa ccagcattta gtaccagcat atggttcata
3781 tgcaaataat actttcccca aaatctttct gggctaggct attttcttgc tatgcttcct
3841 gcacccaacc agcagaattc ttccagggtg gaggaactaa tcagcttgtt ctccaacagt
3901 tctgaagcca acccacaaat ctttgaggaa aaggggtcac tttgtttact attctcttgg
3961 agatggaagt gattctgctc ttccatttgg gtatattatt tcaagggtat ttcttcttaa
4021 aaatcttgga aagcctaaga gagttaaagg catcctggtt ttgtttcatt ttgctctgtt
4081 ttaaatccat atgcaaataa aactgcttct ctcttacact gcttgaacta gaaaatcagc
4141 tttttaatgt aggttaccac ttataagcac aaaagaaaca tgtataagaa accagattta
4201 agtgttttaa ataaaatgta aacagttttt atttggtaga gatgactcat ggaaaaattg
4261 tgttggcttg gtctgcatgt ttaatgatgt gcttgtatat cgattagctg tgtcactttt
4321 aaataagaag tccacacaag caagccaaat ttttagatga cgaagtccat aaataactag
4381 agaatttttg ttatctgttg ttaagttgaa atgtataatc atttatcact aaattgcaca
4441 ttgcctttat ttatttgtgc tctgtttttg gtttacagtg taataatacc tcatttaaaa
4501 aataaaaacc actactgtta cattttatta atttaaaaag ctagaaaatt catgtagtta
4561 ctttttttac atatataatc tgttaatgaa ttattgattt ttgtatctgc cacagtaaat
4621 taaagcatta cacagtattt atcagtattt tttaaacatc ctgtcctttt ttaaaatctt
4681 tgcttagtca gtcatatttt tgtctgtatg attagaagtt tttacgtcct tccttttttg
4741 tacaaatctg tattgtatta atttctggat gcaatttttc aaatattaaa attatacagt
4801 cagtcagaaa aaaaaaaaaa aaa
//