LOCUS BC035815 2488 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens potassium voltage-gated channel, subfamily H
(eag-related), member 7, mRNA (cDNA clone MGC:45986 IMAGE:5769938),
complete cds.
ACCESSION BC035815
VERSION BC035815.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2488)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2488)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 79 Row: p Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27886664.
FEATURES Location/Qualifiers
source 1..2488
/db_xref="H-InvDB:HIT000051521"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:45986 IMAGE:5769938"
/tissue_type="Brain, fetal, whole pooled"
/clone_lib="NIH_MGC_121"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2488
/gene="KCNH7"
/gene_synonym="ERG3"
/gene_synonym="HERG3"
/gene_synonym="Kv11.3"
/gene_synonym="MGC45986"
/db_xref="GeneID:90134"
/db_xref="HGNC:HGNC:18863"
/db_xref="MIM:608169"
CDS 213..2411
/gene="KCNH7"
/gene_synonym="ERG3"
/gene_synonym="HERG3"
/gene_synonym="Kv11.3"
/gene_synonym="MGC45986"
/codon_start=1
/product="potassium voltage-gated channel, subfamily H
(eag-related), member 7"
/protein_id="AAH35815.1"
/db_xref="GeneID:90134"
/db_xref="HGNC:HGNC:18863"
/db_xref="MIM:608169"
/translation="MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYC
NDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKN
GSTFICNTHIIPVKNQEGVAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGF
KFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKA
LIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSV
HDIEGFGVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSE
VKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFT
ILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLI
VDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSG
SDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAI
GNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFG
NVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRF
HQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSVFQNESAAGIIVIAKME"
BASE COUNT 773 a 551 c 543 g 621 t
ORIGIN
1 ggccccctcc ggaaggtgag gggaatggat tggactccgg tggggaaagc gggtgtctag
61 aagtggtgct aatgggaaga gaattctggt ttcaaaagag gatgctctgc cacaaagagc
121 ggctcgcgcg ctggcctggg ctctagccga ggagagatcc cgggagaact ccagagctcc
181 gggggagcgc tcctcggaag accggggcca acatgcctgt gcgcaggggg catgtggcac
241 cacaaaatac atttctgggg accatcattc ggaaatttga agggcaaaat aaaaaattta
301 tcattgcaaa tgccagagtg cagaactgtg ccatcattta ttgcaacgat gggttctgtg
361 agatgactgg tttctccagg ccagatgtca tgcaaaagcc atgcacctgc gactttctcc
421 atggacccga gaccaagagg catgatattg cccaaattgc ccaggcattg ctggggtcag
481 aagagaggaa agtggaggtc acctactatc acaaaaatgg gtccactttt atttgtaaca
541 ctcacataat tccagtgaaa aaccaagagg gcgtggctat gatgttcatc attaattttg
601 aatatgtgac ggataatgaa aacgctgcca ccccagagag ggtaaaccca atattaccaa
661 tcaaaactgt aaaccggaaa ttttttgggt tcaaattccc tggtctgaga gttctcactt
721 acagaaagca gtccttacca caagaagacc ccgatgtggt ggtcatcgat tcatctaaac
781 acagtgatga ttcagtagcc atgaagcatt ttaagtctcc tacaaaagaa agctgcagcc
841 cctctgaagc agatgacaca aaagctttga tacagcccag caaatgttct cccttggtga
901 atatatccgg acctcttgac cattcctctc ccaaaaggca atgggaccga ctctaccctg
961 acatgctgca gtcaagttcc cagctgtccc attccagatc aagggaaagc ttatgtagta
1021 tacggagagc atcttcggtc catgatatag aaggattcgg cgtccacccc aagaacatat
1081 ttagagaccg acatgccagc gaagggcctt ttaatcatat caagtcaagc ctcctgggat
1141 ccacatcaga ttcaaacctc aacaaataca gcaccattaa caagattcca cagctcactc
1201 tgaatttttc agaggtcaaa actgagaaaa agaattcatc acctccttct tcagataaaa
1261 ccattattgc acccaaggtt aaagatcgaa cacacaatgt gactgagaaa gtgacccagg
1321 ttctctcttt aggagcagat gtcctacctg aatacaaact gcagacacca cgcatcaaca
1381 agtttacgat attgcactac agccctttca aggcagtctg ggactggctt atcctgctgt
1441 tggtcatata cactgctata tttactccct actctgcagc cttcctcctc aatgacagag
1501 aagaacagaa aagacgagaa tgtggctatt cttgtagccc tttgaatgtg gtagacttga
1561 ttgtggatat tatgtttatc atagatattt taataaactt cagaacaaca tatgtaaatc
1621 agaatgaaga agtggtaagt gatcccgcca aaatagcaat acactacttc aaaggctggt
1681 tcctgattga catggttgca gcaattcctt ttgacttgct gatttttgga tcaggttctg
1741 atgagacaac aacattaatt ggtcttttga agactgcccg actcctccgt cttgtgcgcg
1801 tggccaggaa actggatcga tattcagaat atggcgctgc tgttctaatg ctcttaatgt
1861 gcatctttgc cctgattgct cactggctgg cttgcatttg gtatgcgatt gggaatgtag
1921 aaaggcctta cctgactgac aaaatcggat ggttggattc cttaggacag caaattggga
1981 aacgttacaa tgacagtgac tcaagttctg gaccatccat taaagacaaa tacgtcacag
2041 cactttattt taccttcagc agtttaacca gtgtaggatt cgggaatgtg tctcctaaca
2101 cgaattcgga gaaaatcttt tcaatttgtg tcatgttgat tggctcacta atgtatgcaa
2161 gcatttttgg gaatgtatct gcaattatcc aaagactata ctcgggaact gccaggtacc
2221 acatgcagat gctgcgagta aaagagttca ttcgctttca ccaaatcccc aaccctctga
2281 ggcaacgtct tgaagaatat ttccagcacg catggactta caccaatggc attgacatga
2341 acatggtatg tatgtctgtt ttccaaaatg aaagtgccgc aggcattata gtgatagcca
2401 aaatggaata aaagccggaa tcaccagctt tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//