LOCUS BC032697 1073 bp mRNA linear HUM 06-OCT-2003
DEFINITION Homo sapiens fibroblast growth factor 1 (acidic), mRNA (cDNA clone
MGC:44867 IMAGE:5403677), complete cds.
ACCESSION BC032697
VERSION BC032697.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1073)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1073)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 69 Row: d Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15055546.
FEATURES Location/Qualifiers
source 1..1073
/db_xref="H-InvDB:HIT000041675"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:44867 IMAGE:5403677"
/tissue_type="Liver, adenocarcinoma"
/clone_lib="NIH_MGC_90"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1073
/gene="FGF1"
/gene_synonym="AFGF"
/gene_synonym="ECGF"
/gene_synonym="ECGF-beta"
/gene_synonym="ECGFA"
/gene_synonym="ECGFB"
/gene_synonym="FGF-alpha"
/gene_synonym="FGFA"
/gene_synonym="GLIO703"
/gene_synonym="HBGF1"
/db_xref="GeneID:2246"
/db_xref="MIM:131220"
CDS 91..558
/gene="FGF1"
/gene_synonym="AFGF"
/gene_synonym="ECGF"
/gene_synonym="ECGF-beta"
/gene_synonym="ECGFA"
/gene_synonym="ECGFB"
/gene_synonym="FGF-alpha"
/gene_synonym="FGFA"
/gene_synonym="GLIO703"
/gene_synonym="HBGF1"
/codon_start=1
/product="FGF1 protein"
/protein_id="AAH32697.1"
/db_xref="GeneID:2246"
/db_xref="MIM:131220"
/translation="MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDG
TVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLE
RLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD"
misc_feature 157..543
/gene="FGF1"
/gene_synonym="AFGF"
/gene_synonym="ECGF"
/gene_synonym="ECGF-beta"
/gene_synonym="ECGFA"
/gene_synonym="ECGFB"
/gene_synonym="FGF-alpha"
/gene_synonym="FGFA"
/gene_synonym="GLIO703"
/gene_synonym="HBGF1"
/note="FGF; Region: Fibroblast growth factor. Fibroblast
growth factors are a family of proteins involved in growth
and differentiation in a wide range of contexts. These
growth factors cause dimerisation of their tyrosine kinase
receptors leading to intracellular signaling. There are
currently four known tyrosine kinase receptors for
fibroblast growth factors. These receptors can each bind
several different members of this family. Members of this
family have a beta trefoil structure"
/db_xref="CDD:pfam00167"
BASE COUNT 372 a 241 c 242 g 218 t
ORIGIN
1 ccacgcgtcc gaaaaaatac tgttggcagc agcacaatgt ttgggctaag acctggtctt
61 gaaagcgcca caagcagcag ctgctgagcc atggctgaag gggaaatcac caccttcaca
121 gccctgaccg agaagtttaa tctgcctcca gggaattaca agaagcccaa actcctctac
181 tgtagcaacg ggggccactt cctgaggatc cttccggatg gcacagtgga tgggacaagg
241 gacaggagcg accagcacat tcagctgcag ctcagtgcgg aaagcgtggg ggaggtgtat
301 ataaagagta ccgagactgg ccagtacttg gccatggaca ccgacgggct tttatacggc
361 tcacagacac caaatgagga atgtttgttc ctggaaaggc tggaggagaa ccattacaac
421 acctatatat ccaagaagca tgcagagaag aattggtttg ttggcctcaa gaagaatggg
481 agctgcaaac gcggtcctcg gactcactat ggccagaaag caatcttgtt tctccccctg
541 ccagtctctt ctgattaaag agatctgttc tgggtgttga ccactccaga gaagtttcga
601 ggggtcctca cctggttgac ccaaaaatgt tcccttgacc attggctgcg ctaaccccca
661 gcccacagag cctgaatttg taagcaactt gcttctaaat gcccagttca cttctttgca
721 gagcctttta cccctgcaca gtttagaaca gagggaccaa attgcttcta ggagtcaact
781 ggctggccag tctgggtctg ggtttggatc tccaattgcc tcttgcaggc tgagtccctc
841 aatgcaaaag tggggctaaa tgaagtgtgt taaggggtca gctaagtggg acattagtaa
901 ctgcacacta tttccctcta ctgagtaaac cctatctgtg attcccccaa aaaaaaaaaa
961 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1021 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//